SDCBP2 and NFU1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SDCBP2	NFU1
Description		syndecan binding protein 2	NFU1 iron-sulfur cluster scaffold
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Membrane Nuclear Speck Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Lipid Binding Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity	Iron Ion Binding Protein Binding Metal Ion Binding Iron-sulfur Cluster Binding 2 Iron, 2 Sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	Nervous System Development Cell Population Proliferation Intracellular Signal Transduction Intracellular Transport	Iron-sulfur Cluster Assembly Protein Maturation
Pathways			Protein lipoylation
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31152163) Metabolite levels ( 23823483)
Interacting Genes		66 interacting genes: ADAP1 AKAP17A AP1M1 ARF4 BEND7 C1orf35 CHCHD1 CRCT1 CRY2 CT45A1 CT45A10 CT45A3 CT45A5 CTH DMC1 DPPA2 EIF1AD FAM133A FAM13C FAM9B FBXO28 GABRA3 HSBP1 LGALS14 LGALS2 LYAR MED4 NFASC NFU1 NKAPD1 NOP56 NPM2 NRXN1 NUF2 PAFAH1B3 PDCD6IP PHC1 PRM2 PRPF38A PRPF40A PRR13 PTMS RNF111 RNPS1 RPL22 RPL22L1 RPL41 SDCBP SEC23A SREK1IP1 SYT17 TCP11L1 TDO2 THAP6 TIFA TM4SF1 TNNT1 TNP1 TRAF1 VAX1 VPS25 YTHDC1 ZCCHC10 ZCCHC17 ZNF581 ZRSR2	23 interacting genes: AGTRAP APOC1 APOC2 APOC4 CALCOCO2 CIDEB CMTM5 COIL DESI2 EPM2A FKBP7 HIRA HSPB1 MDK MORN3 NOA1 RHBDD2 SDCBP2 SH3BP4 TFIP11 TRIM23 ZNF688 ZSCAN5A
Entrez ID		27111	27247
HPRD ID		18032	12163
Ensembl ID		ENSG00000125775	ENSG00000169599
Uniprot IDs		Q9H190	Q9UMS0
PDB IDs			2LTM 2M5O
Enriched GO Terms of Interacting Partners?		Protein Binding	High-density Lipoprotein Particle Very-low-density Lipoprotein Particle Acylglycerol Homeostasis Negative Regulation Of Very-low-density Lipoprotein Particle Clearance Chylomicron Remnant Clearance Triglyceride-rich Lipoprotein Particle Clearance Triglyceride Homeostasis Regulation Of Triglyceride Metabolic Process Regulation Of Phospholipid Catabolic Process Lipase Inhibitor Activity Positive Regulation Of Autophagy Very-low-density Lipoprotein Particle Assembly Regulation Of Autophagy Chylomicron Phospholipid Efflux Negative Regulation Of Lipoprotein Particle Clearance Identical Protein Binding Negative Regulation Of Cholesterol Transport Plasma Lipoprotein Particle Assembly Protein-lipid Complex Assembly Plasma Lipoprotein Particle Clearance Lipid Transport Cholesterol Efflux Positive Regulation Of Catabolic Process Negative Regulation Of Receptor-mediated Endocytosis Lipoprotein Metabolic Process Lipid Storage Regulation Of Phospholipid Metabolic Process Plasma Lipoprotein Particle Remodeling Protein-containing Complex Remodeling Negative Regulation Of Lipid Transport Negative Regulation Of Phosphatidylcholine Catabolic Process Negative Regulation Of Protein Kinase C Signaling Defecation HIR Complex Negative Regulation Of Hydrolase Activity Carbohydrate Phosphatase Activity Lipid Homeostasis Regulation Of Fatty Acid Biosynthetic Process Positive Regulation Of Very-low-density Lipoprotein Particle Remodeling Spliceosomal Complex Disassembly
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