SDCBP2 and ZRSR2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SDCBP2	ZRSR2
Description		syndecan binding protein 2	zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Membrane Nuclear Speck Extracellular Exosome	Nucleus Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex U2AF Complex Ribonucleoprotein Complex
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Lipid Binding Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity	Nucleic Acid Binding RNA Binding Protein Binding Zinc Ion Binding Pre-mRNA 3'-splice Site Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Nervous System Development Cell Population Proliferation Intracellular Signal Transduction Intracellular Transport	Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing
Pathways			mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31152163) Metabolite levels ( 23823483)
Interacting Genes		66 interacting genes: ADAP1 AKAP17A AP1M1 ARF4 BEND7 C1orf35 CHCHD1 CRCT1 CRY2 CT45A1 CT45A10 CT45A3 CT45A5 CTH DMC1 DPPA2 EIF1AD FAM133A FAM13C FAM9B FBXO28 GABRA3 HSBP1 LGALS14 LGALS2 LYAR MED4 NFASC NFU1 NKAPD1 NOP56 NPM2 NRXN1 NUF2 PAFAH1B3 PDCD6IP PHC1 PRM2 PRPF38A PRPF40A PRR13 PTMS RNF111 RNPS1 RPL22 RPL22L1 RPL41 SDCBP SEC23A SREK1IP1 SYT17 TCP11L1 TDO2 THAP6 TIFA TM4SF1 TNNT1 TNP1 TRAF1 VAX1 VPS25 YTHDC1 ZCCHC10 ZCCHC17 ZNF581 ZRSR2	23 interacting genes: APP CCNL1 CLK1 CLK2 DSCR9 DVL3 KHDC4 LUC7L2 PRPF6 REP15 RPS27L SDCBP2 SPATS2L SRPK2 SRRM4 SRSF1 SRSF2 SRSF5 SSX2IP TEPSIN TNFAIP8L1 U2AF1 U2AF2
Entrez ID		27111	8233
HPRD ID		18032	02068
Ensembl ID		ENSG00000125775	ENSG00000169249
Uniprot IDs		Q9H190	A0A8I5KSD0 Q15696
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding	Regulation Of RNA Splicing Nuclear Speck Protein-RNA Complex Assembly RNA Splicing MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing MRNA Metabolic Process MRNA Splice Site Recognition RNA Binding RNA Processing Regulation Of Alternative MRNA Splicing, Via Spliceosome Protein-containing Complex Assembly Spliceosomal Complex Regulation Of MRNA Metabolic Process Protein-containing Complex Organization RNA Splicing, Via Transesterification Reactions MRNA Binding RS Domain Binding Positive Regulation Of RNA Splicing Pre-mRNA 3'-splice Site Binding U2AF Complex Spliceosomal Complex Assembly RNA Metabolic Process Protein Kinase B Binding Cellular Component Assembly MRNA Splicing, Via Spliceosome Nucleus Catalytic Step 2 Spliceosome U2-type Prespliceosome Protein Serine/threonine/tyrosine Kinase Activity Liver Regeneration Neuron Maturation Nucleoplasm Nucleic Acid Binding Nucleic Acid Metabolic Process Frizzled Binding Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Glucose Transporter Complex Coated Vesicle Membrane
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