SDCBP2 and NFASC

Number of citations of the paper that reports this interaction (PubMedID 11152476)
0

Data Source:
HPRD (two hybrid, in vitro)

		SDCBP2	NFASC
Description		syndecan binding protein 2	neurofascin
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Membrane Nuclear Speck Extracellular Exosome	Plasma Membrane Focal Adhesion Membrane Axon Paranodal Junction Node Of Ranvier Axon Initial Segment Anchoring Junction Ficolin-1-rich Granule Membrane
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Lipid Binding Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity	Protein Binding Cell-cell Adhesion Mediator Activity
	Biological Process	Nervous System Development Cell Population Proliferation Intracellular Signal Transduction Intracellular Transport	Cell Adhesion Axon Guidance Brain Development Peripheral Nervous System Development Myelination Cell-cell Adhesion
Pathways			Interaction between L1 and Ankyrins Neurofascin interactions Neurofascin interactions Neutrophil degranulation
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31152163) Metabolite levels ( 23823483)	Age at first sexual intercourse ( 34211149) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Blood protein levels ( 30072576) Clozapine-induced agranulocytosis ( 25187353) Dental caries ( 23064961) Diisocyanate-induced asthma ( 25918132) Disrupted circadian rhythm (low relative amplitude of rest-activity cycles) ( 30120083) General risk tolerance (MTAG) ( 30643258) High myopia ( 32428537) Mean platelet volume ( 27863252 32888494) Platelet count ( 32888494) Regular attendance at a religious group ( 29970889)
Interacting Genes		66 interacting genes: ADAP1 AKAP17A AP1M1 ARF4 BEND7 C1orf35 CHCHD1 CRCT1 CRY2 CT45A1 CT45A10 CT45A3 CT45A5 CTH DMC1 DPPA2 EIF1AD FAM133A FAM13C FAM9B FBXO28 GABRA3 HSBP1 LGALS14 LGALS2 LYAR MED4 NFASC NFU1 NKAPD1 NOP56 NPM2 NRXN1 NUF2 PAFAH1B3 PDCD6IP PHC1 PRM2 PRPF38A PRPF40A PRR13 PTMS RNF111 RNPS1 RPL22 RPL22L1 RPL41 SDCBP SEC23A SREK1IP1 SYT17 TCP11L1 TDO2 THAP6 TIFA TM4SF1 TNNT1 TNP1 TRAF1 VAX1 VPS25 YTHDC1 ZCCHC10 ZCCHC17 ZNF581 ZRSR2	12 interacting genes: ABI1 ABI2 ANK1 CNTNAP1 DCX NRCAM SCN1B SCN3B SCNN1B SDCBP SDCBP2 TNR
Entrez ID		27111	23114
HPRD ID		18032	12372
Ensembl ID		ENSG00000125775	ENSG00000163531
Uniprot IDs		Q9H190	A0A7P0Z4R6 B4DRH7 O94856
PDB IDs			3P3Y 3P40
Enriched GO Terms of Interacting Partners?		Protein Binding	Action Potential Propagation Neuronal Action Potential Propagation Cytoskeletal Anchor Activity Action Potential System Development Neuron Migration Cell Projection Organization Plasma Membrane Bounded Cell Projection Organization Sodium Channel Inhibitor Activity Sodium Channel Complex Actin-based Cell Projection Regulation Of Atrial Cardiac Muscle Cell Membrane Depolarization Nervous System Development SCAR Complex Cell Projection Morphogenesis Voltage-gated Sodium Channel Complex Membrane Depolarization During Cardiac Muscle Cell Action Potential SH3 Domain Binding Filopodium Tip Neuron Projection Membrane Depolarization During Action Potential Sodium Ion Transmembrane Transport Transmembrane Transporter Binding Central Nervous System Development Regulation Of Neuron Projection Development Regulation Of Membrane Potential Cell Migration Nervous System Process Cell Junction Organization System Process Sodium Channel Regulator Activity Sodium Ion Transport Positive Regulation Of Sodium Ion Transport Neuron Projection Development Sodium Channel Activity Cardiac Muscle Cell Action Potential Involved In Contraction Cytoskeleton Organization Muscle Contraction Regulation Of Heart Rate By Cardiac Conduction Cardiac Muscle Cell Action Potential Cardiac Muscle Contraction Neuron Projection Guidance Axon Guidance Cell Motility Cardiac Conduction Neuromuscular Process Controlling Balance Regulation Of Cellular Component Organization Regulation Of Membrane Depolarization Membrane Depolarization Synapse Organization
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