GORAB and RCHY1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)
HPRD (in vivo, in vitro, two hybrid)

		GORAB	RCHY1
Gene Name		golgin, RAB6-interacting	ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Nuclear Speck
	Molecular Function	Protein Binding	P53 Binding Ubiquitin-protein Transferase Activity Receptor Binding Protein Binding Zinc Ion Binding Ligase Activity Protein Homodimerization Activity
	Biological Process		Protein Ubiquitination Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination
Pathways			Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS			Response to tocilizumab in rheumatoid arthritis ( 22491018)
Protein-Protein Interactions		12 interactors: APP BET1L FARSA HOXD9 HSD17B7 MDM2 NEDD4L NKG7 PTAFR RCHY1 SCYL1 ZNF16	61 interactors: ADAMTSL4 AIG1 AOX1 AR ARF4 ATN1 BIRC3 C19orf80 CAMK2A CAMK2G CDK9 CDKN1B CHD8 CHEK2 COPE COX6C CYBA DCUN1D5 F7 FADS6 GFI1B GORAB HRG KAT5 KLHL41 KRTAP9-2 LIMS2 MDM2 MEOX2 MSH3 MT2A NKD2 NLK NOTCH2NL PGLS PLAGL2 PMM1 PRDX4 RAB11A RBM38 RILP RPLP1 RPN2 SEMA4C SERPINA1 SERPINA5 SERTAD1 SRPRB TAOK2 TMBIM1 TMEM14C TMEM184A TP53 TP63 TP73 TRIM8 UBASH3B UBE2D2 UBE2D4 WDR74 ZNF160
Entrez ID		92344	25898
HPRD ID		12144	07607
Ensembl ID		ENSG00000120370	ENSG00000163743
Uniprot IDs		B3KQ87 Q5T7V8	C7E542 E7EMC8 E7ETW5 J3KPI0 Q96PM5
PDB IDs			2JRJ 2K2C 2K2D
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cell Cycle Phase Transition Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Positive Regulation Of Cell Cycle Process Regulation Of Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Proteolysis Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Alcohol Metabolic Process Cellular Response To UV-C Cellular Response To Vitamin B1 Cellular Response To Sodium Dodecyl Sulfate Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Catabolic Process Regulation Of Retrograde Vesicle-mediated Transport, Golgi To ER Synaptic Growth At Neuromuscular Junction Positive Regulation Of Caveolin-mediated Endocytosis Regulation Of Cell Cycle Process Cholesterol Metabolic Process Adult Locomotory Behavior Positive Regulation Of Mitotic Cell Cycle Ubiquitin-dependent Protein Catabolic Process Cellular Metabolic Process Collateral Sprouting In Absence Of Injury Modification-dependent Protein Catabolic Process RNA Metabolic Process Sterol Metabolic Process Positive Regulation Of Protein Metabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Phosphatidylinositol-mediated Signaling Phenylalanyl-tRNA Aminoacylation Inositol Trisphosphate Biosynthetic Process Traversing Start Control Point Of Mitotic Cell Cycle Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Protein Catabolic Process Protein Ubiquitination Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Metabolic Process Biosynthetic Process Gene Expression Positive Regulation Of Cellular Protein Catabolic Process Protein Modification By Small Protein Conjugation Response To Vitamin B1 Response To Ether Collateral Sprouting Axon Midline Choice Point Recognition Protein Catabolic Process Adult Behavior Negative Regulation Of Sodium Ion Transmembrane Transporter Activity	Signal Transduction In Response To DNA Damage DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription DNA Damage Response, Signal Transduction By P53 Class Mediator Mitotic DNA Damage Checkpoint DNA Damage Checkpoint Mitotic DNA Integrity Checkpoint Signal Transduction By P53 Class Mediator Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Regulation Of Protein Metabolic Process Response To Stress Regulation Of Cell Cycle Phase Transition Cell Cycle Checkpoint Mitotic Cell Cycle Checkpoint Response To Gamma Radiation Negative Regulation Of Cellular Metabolic Process Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Cellular Metabolic Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of Cellular Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Apoptotic Process Negative Regulation Of Mitotic Cell Cycle Response To Ionizing Radiation Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cellular Protein Metabolic Process Cellular Response To Stress Negative Regulation Of Biosynthetic Process Regulation Of Cell Cycle Process Regulation Of Cell Death Regulation Of Metabolic Process Regulation Of Cell Cycle Arrest Mitotic Cell Cycle Process Cellular Response To DNA Damage Stimulus Cell Cycle Process Positive Regulation Of Metabolic Process Cell Death Death Regulation Of Mitotic Cell Cycle Regulation Of Cellular Process Response To Abiotic Stimulus Positive Regulation Of Blood Vessel Remodeling Negative Regulation Of Apoptotic Process Regulation Of Body Fluid Levels Negative Regulation Of Programmed Cell Death
Tagcloud ?			20s alters animal conserved correlatively crucial degradation display e3 establish handful homeodomain hox hoxa2 interacts ligase modes multitude pirh2 promotes proteasomal proteasome regulators reports reveal stabilization subunits ubiquitin ubiquitination
Tagcloud (Difference) ?			20s alters animal conserved correlatively crucial degradation display e3 establish handful homeodomain hox hoxa2 interacts ligase modes multitude pirh2 promotes proteasomal proteasome regulators reports reveal stabilization subunits ubiquitin ubiquitination
Tagcloud (Intersection) ?