GORAB and ZNF16

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		GORAB	ZNF16
Description		golgin, RAB6 interacting	zinc finger protein 16
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytosol	Nucleus Nucleoplasm Nucleolus
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Hair Follicle Morphogenesis Positive Regulation Of Smoothened Signaling Pathway Non-motile Cilium Assembly	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Population Proliferation Positive Regulation Of Metabolic Process Positive Regulation Of Kinase Activity Negative Regulation Of Apoptotic Process Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of Megakaryocyte Differentiation Regulation Of Multicellular Organismal Process Cell Division Positive Regulation Of Cell Division Cellular Response To Sodium Dodecyl Sulfate Positive Regulation Of Cell Cycle Phase Transition
Pathways
Drugs
Diseases		Geroderma osteodysplasticum
GWAS		A body shape index ( 34021172) Atrial fibrillation ( 29892015) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Heel bone mineral density ( 30598549) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Male-pattern baldness ( 27182965 28196072) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-hip ratio ( 25673412) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI in inactive individuals ( 28448500) Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 28448500 25673412)	Logical memory (immediate recall) in normal cognition ( 29274321) White matter hyperintensity burden ( 25663218)
Interacting Genes		66 interacting genes: ABHD16A APOD APP ARF1 ARF3 ARF5 BCL2L1 BCL2L2 BET1L BNIP2 C3orf52 CD81 CES1 CLDN19 CLN6 CMTM7 CNIH2 COPB1 CTSA CXCL16 CXCL9 EMD FARSA FBXO7 GIMAP5 HOXD9 HSD17B7 ITGAM LPAR3 LRP10 MDM2 MS4A1 NEDD4L NKG7 NRM PAEP PLPP6 PTAFR PTPN9 RAB6A RCHY1 SCYL1 SEC22B SELENOK SNAPC5 STX12 STX8 TMEM11 TMEM120B TMEM128 TMEM14C TMEM187 TMEM19 TMEM229B TMEM60 TMEM86A TRAF3IP3 TSPAN33 VAMP3 VAMP5 VEZT VKORC1 VKORC1L1 WFDC2 ZFPL1 ZNF16	6 interacting genes: AQP1 FAIM GORAB ZBTB47 ZCCHC17 ZNF101
Entrez ID		92344	7564
HPRD ID		12144	03163
Ensembl ID		ENSG00000120370	ENSG00000170631
Uniprot IDs		A0A8I5KW31 B3KQ87 Q5T7V8	P17020
PDB IDs
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Membrane SNAP Receptor Activity Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Golgi Vesicle Transport Peptidyl-glutamic Acid Carboxylation Oxidoreductase Activity, Acting On CH Or CH2 Groups, Disulfide As Acceptor Vitamin-K-epoxide Reductase (warfarin-sensitive) Activity Regulation Of Transport SNARE Complex Endoplasmic Reticulum Endosome To Plasma Membrane Transport Vesicle Nuclear Inner Membrane Golgi Apparatus Positive Regulation Of Protein Catabolic Process Cellular Localization Membrane Organization Amyloid Fibril Formation Establishment Of Protein Localization Membrane Fusion Cholesterol Biosynthetic Process Intracellular Transport Bcl-2 Family Protein Complex Tetraspanin-enriched Microdomain Regulation Of Protein Catabolic Process Endomembrane System Sterol Biosynthetic Process Regulation Of Protein Localization Establishment Of Localization In Cell Transport Vesicle Quinone Binding Protein Transport Regulation Of Cellular Localization Regulation Of T Cell Migration Cell Activation Intracellular Protein Localization Intracellular Protein Transport Cholesterol Metabolic Process COPI Vesicle Coat Vitamin K Metabolic Process	Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Nitric Oxide Transmembrane Transporter Activity Metanephric Proximal Convoluted Tubule Segment 2 Development Metanephric Glomerulus Vasculature Development Glycerol Transmembrane Transporter Activity Corticotropin Secretion Nitric Oxide Transport Establishment Or Maintenance Of Actin Cytoskeleton Polarity Cerebrospinal Fluid Secretion Renal Water Absorption Carbon Dioxide Transmembrane Transporter Activity Positive Regulation Of Saliva Secretion Glomerulus Vasculature Development Water Transmembrane Transporter Activity Cellular Response To Mercury Ion Transepithelial Water Transport Hydrogen Peroxide Transmembrane Transport Hydrogen Peroxide Channel Activity Potassium Ion Transmembrane Transporter Activity Intracellularly CGMP-activated Cation Channel Activity Carbon Dioxide Transmembrane Transport Lipid Digestion Pancreatic Juice Secretion Ankyrin-1 Complex Glycerol Transmembrane Transport Intracellular Water Homeostasis Renal Water Transport Regulation Of Saliva Secretion Ammonium Channel Activity Polyol Transmembrane Transport Response To Mercury Ion Ammonium Transmembrane Transport Cellular Response To Salt Stress Positive Regulation Of Digestive System Process Epithelial Fluid Transport Metanephric Nephron Tubule Development Lateral Ventricle Development Water Channel Activity Metanephric Tubule Development Metanephric Epithelium Development Carbon Dioxide Transport Cellular Response To Nitric Oxide Positive Regulation Of Fibroblast Migration Glomerular Filtration Cellular Response To Reactive Nitrogen Species Cellular Hyperosmotic Response Renal Water Homeostasis Response To Salt Stress Fibroblast Migration
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