GORAB and HOXD9

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		GORAB	HOXD9
Description		golgin, RAB6 interacting	homeobox D9
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytosol	Chromatin Nucleus Nucleoplasm Nucleolus
	Molecular Function	Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Hair Follicle Morphogenesis Positive Regulation Of Smoothened Signaling Pathway Non-motile Cilium Assembly	Negative Regulation Of Transcription By RNA Polymerase II DNA-templated Transcription Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Single Fertilization Skeletal Muscle Tissue Development Adult Locomotory Behavior Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Regulation Of Gene Expression Mammary Gland Development Embryonic Forelimb Morphogenesis Forelimb Morphogenesis Hindlimb Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis Embryonic Skeletal System Development Peripheral Nervous System Neuron Development
Pathways
Drugs
Diseases		Geroderma osteodysplasticum
GWAS		A body shape index ( 34021172) Atrial fibrillation ( 29892015) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Heel bone mineral density ( 30598549) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Male-pattern baldness ( 27182965 28196072) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-hip ratio ( 25673412) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI in inactive individuals ( 28448500) Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 28448500 25673412)	Estimated glomerular filtration rate ( 31015462) Magnesium levels ( 20700443) Male-pattern baldness ( 28196072)
Interacting Genes		66 interacting genes: ABHD16A APOD APP ARF1 ARF3 ARF5 BCL2L1 BCL2L2 BET1L BNIP2 C3orf52 CD81 CES1 CLDN19 CLN6 CMTM7 CNIH2 COPB1 CTSA CXCL16 CXCL9 EMD FARSA FBXO7 GIMAP5 HOXD9 HSD17B7 ITGAM LPAR3 LRP10 MDM2 MS4A1 NEDD4L NKG7 NRM PAEP PLPP6 PTAFR PTPN9 RAB6A RCHY1 SCYL1 SEC22B SELENOK SNAPC5 STX12 STX8 TMEM11 TMEM120B TMEM128 TMEM14C TMEM187 TMEM19 TMEM229B TMEM60 TMEM86A TRAF3IP3 TSPAN33 VAMP3 VAMP5 VEZT VKORC1 VKORC1L1 WFDC2 ZFPL1 ZNF16	9 interacting genes: BARX1 ETV5 FCMR GORAB HMGB1 HOXC9 MEIS1 PBX1 PKNOX1
Entrez ID		92344	3235
HPRD ID		12144	00865
Ensembl ID		ENSG00000120370	ENSG00000128709
Uniprot IDs		A0A8I5KW31 B3KQ87 Q5T7V8	P28356
PDB IDs
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Membrane SNAP Receptor Activity Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Golgi Vesicle Transport Peptidyl-glutamic Acid Carboxylation Oxidoreductase Activity, Acting On CH Or CH2 Groups, Disulfide As Acceptor Vitamin-K-epoxide Reductase (warfarin-sensitive) Activity Regulation Of Transport SNARE Complex Endoplasmic Reticulum Endosome To Plasma Membrane Transport Vesicle Nuclear Inner Membrane Golgi Apparatus Positive Regulation Of Protein Catabolic Process Cellular Localization Membrane Organization Amyloid Fibril Formation Establishment Of Protein Localization Membrane Fusion Cholesterol Biosynthetic Process Intracellular Transport Bcl-2 Family Protein Complex Tetraspanin-enriched Microdomain Regulation Of Protein Catabolic Process Endomembrane System Sterol Biosynthetic Process Regulation Of Protein Localization Establishment Of Localization In Cell Transport Vesicle Quinone Binding Protein Transport Regulation Of Cellular Localization Regulation Of T Cell Migration Cell Activation Intracellular Protein Localization Intracellular Protein Transport Cholesterol Metabolic Process COPI Vesicle Coat Vitamin K Metabolic Process	Eye Development Sensory Organ Development Chromatin DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity DNA Binding Regulation Of Transcription By RNA Polymerase II Pattern Specification Process Sequence-specific DNA Binding Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Hemopoiesis Regulation Of Neuron Differentiation Sequence-specific Double-stranded DNA Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Spleen Development Transcription Regulator Complex Lymphocyte Differentiation Transcription Cis-regulatory Region Binding Regulation Of RNA Metabolic Process Regionalization Embryonic Skeletal System Development Animal Organ Development Developmental Process Regulation Of Nucleobase-containing Compound Metabolic Process Mononuclear Cell Differentiation Calcium-dependent Protein Kinase Regulator Activity Regulation Of Restriction Endodeoxyribonuclease Activity Transcription Repressor Complex Positive Regulation Of Myeloid Progenitor Cell Differentiation High-affinity IgM Receptor Activity Negative Regulation Of Neuron Differentiation RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Cell Development Positive Regulation Of Cell Population Proliferation Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Leukocyte Differentiation Negative Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Negative Regulation Of Apoptotic Cell Clearance RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Polymeric Immunoglobulin Binding Cellular Developmental Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of RNA Metabolic Process DNA-templated Transcription Hematopoietic Or Lymphoid Organ Development Male Germ-line Stem Cell Asymmetric Division
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