GORAB and TMEM14C

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GORAB	TMEM14C
Description		golgin, RAB6 interacting	transmembrane protein 14C
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytosol	Mitochondrion Mitochondrial Inner Membrane Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding	Protein Binding Transmembrane Transporter Activity
	Biological Process	Hair Follicle Morphogenesis Positive Regulation Of Smoothened Signaling Pathway Non-motile Cilium Assembly	Heme Biosynthetic Process Mitochondrial Transport Erythrocyte Differentiation Transmembrane Transport Regulation Of Heme Biosynthetic Process
Pathways
Drugs
Diseases		Geroderma osteodysplasticum
GWAS		A body shape index ( 34021172) Atrial fibrillation ( 29892015) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Heel bone mineral density ( 30598549) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Male-pattern baldness ( 27182965 28196072) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-hip ratio ( 25673412) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI in inactive individuals ( 28448500) Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 28448500 25673412)	Itch intensity from mosquito bite adjusted by bite size ( 28199695) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261)
Interacting Genes		66 interacting genes: ABHD16A APOD APP ARF1 ARF3 ARF5 BCL2L1 BCL2L2 BET1L BNIP2 C3orf52 CD81 CES1 CLDN19 CLN6 CMTM7 CNIH2 COPB1 CTSA CXCL16 CXCL9 EMD FARSA FBXO7 GIMAP5 HOXD9 HSD17B7 ITGAM LPAR3 LRP10 MDM2 MS4A1 NEDD4L NKG7 NRM PAEP PLPP6 PTAFR PTPN9 RAB6A RCHY1 SCYL1 SEC22B SELENOK SNAPC5 STX12 STX8 TMEM11 TMEM120B TMEM128 TMEM14C TMEM187 TMEM19 TMEM229B TMEM60 TMEM86A TRAF3IP3 TSPAN33 VAMP3 VAMP5 VEZT VKORC1 VKORC1L1 WFDC2 ZFPL1 ZNF16	51 interacting genes: AQP6 ARL13B BCL2L13 BIK CLDN5 COMT COQ9 CPLANE2 CREB3 CREB3L1 CYB5R3 EBP ELOVL7 FAM209A GJB1 GORAB GPR152 GPX8 HSD17B13 KASH5 LMNA LNX1 MARCHF8 MFF MMGT1 MTERF3 MUC1 NCAPH2 NCR3LG1 PDZK1IP1 PLIN3 RCHY1 SAR1A SDC3 SHANK3 SLC10A6 SLC18A1 SLC35H1 SSMEM1 STX1A SYT1 TMEM14B TMEM31 TMEM35A TMEM52B TMEM79 TMEM86B TMX2 VSIR ZDHHC15 ZFYVE27
Entrez ID		92344	51522
HPRD ID		12144	15524
Ensembl ID		ENSG00000120370	ENSG00000111843
Uniprot IDs		A0A8I5KW31 B3KQ87 Q5T7V8	Q9P0S9
PDB IDs			2LOS
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Membrane SNAP Receptor Activity Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Golgi Vesicle Transport Peptidyl-glutamic Acid Carboxylation Oxidoreductase Activity, Acting On CH Or CH2 Groups, Disulfide As Acceptor Vitamin-K-epoxide Reductase (warfarin-sensitive) Activity Regulation Of Transport SNARE Complex Endoplasmic Reticulum Endosome To Plasma Membrane Transport Vesicle Nuclear Inner Membrane Golgi Apparatus Positive Regulation Of Protein Catabolic Process Cellular Localization Membrane Organization Amyloid Fibril Formation Establishment Of Protein Localization Membrane Fusion Cholesterol Biosynthetic Process Intracellular Transport Bcl-2 Family Protein Complex Tetraspanin-enriched Microdomain Regulation Of Protein Catabolic Process Endomembrane System Sterol Biosynthetic Process Regulation Of Protein Localization Establishment Of Localization In Cell Transport Vesicle Quinone Binding Protein Transport Regulation Of Cellular Localization Regulation Of T Cell Migration Cell Activation Intracellular Protein Localization Intracellular Protein Transport Cholesterol Metabolic Process COPI Vesicle Coat Vitamin K Metabolic Process	Membrane Endoplasmic Reticulum Membrane Identical Protein Binding Protein Binding Mitochondrial Membrane Endoplasmic Reticulum Clathrin-sculpted Monoamine Transport Vesicle Membrane Organelle Organization Norepinephrine Transport
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