AURKB and KIF20A

Number of citations of the paper that reports this interaction (PMID 15263015)
55

Data Source:
BioGRID (pull down)

		AURKB	KIF20A
Gene Name		aurora kinase B	kinesin family member 20A
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Condensed Chromosome, Centromeric Region Condensed Nuclear Chromosome, Centromeric Region Nucleus Spindle Cytosol Spindle Microtubule Chromocenter Midbody Spindle Pole Centrosome Chromosome Passenger Complex Spindle Midzone	Nucleoplasm Golgi Apparatus Spindle Kinesin Complex Microtubule Midbody
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Binding ATP Binding Histone Serine Kinase Activity Metal Ion Binding	Microtubule Motor Activity Transporter Activity Protein Binding ATP Binding Microtubule Binding ATPase Activity Protein Kinase Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Mitotic Cell Cycle Negative Regulation Of B Cell Apoptotic Process Protein Phosphorylation Aging Cell Proliferation Attachment Of Spindle Microtubules To Kinetochore Abscission Histone Modification Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Spindle Checkpoint Negative Regulation Of Protein Binding Negative Regulation Of Cytokinesis Positive Regulation Of Cytokinesis Protein Localization To Kinetochore Cellular Response To UV Cleavage Furrow Formation Spindle Stabilization Histone H3-S28 Phosphorylation Protein Autophosphorylation Mitotic Spindle Midzone Assembly Regulation Of Chromosome Segregation	Mitotic Cell Cycle Mitotic Cytokinesis Cytokinesis Cell Separation After Cytokinesis Microtubule Bundle Formation Microtubule-based Movement Metabolic Process Protein Transport Vesicle-mediated Transport
Pathways		Mitotic Prometaphase APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Regulation of mitotic cell cycle Mitotic Anaphase Mitotic Metaphase and Anaphase APC/C-mediated degradation of cell cycle proteins Cell Cycle, Mitotic M Phase	Mitotic Telophase/Cytokinesis MHC class II antigen presentation Kinesins Factors involved in megakaryocyte development and platelet production Cell Cycle, Mitotic M Phase Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		48 interactors: AJUBA ANKZF1 APP BCL2L11 BIRC5 CBX3 CDCA8 CENPA CIB1 CYLD DCUN1D1 DES EVI5 FBXL2 FLOT1 GFAP GNB2L1 GSG2 HIST1H3A HIST2H3C HIST3H3 INCENP KIF20A KLHL13 KLHL21 KLHL9 LATS1 LATS2 MAPRE1 MAPRE2 MAPRE3 NCAPH NDC80 NSUN2 NUF2 PPP2R4 PSMA3 RACGAP1 RASA1 RASSF1 SEPT1 SKA1 SKA3 SUMO1 SUMO2 TACC1 TBL3 TGFBR1	6 interactors: AURKB CDC14A FAM214B RAB6A RAB6B ZRANB2
Entrez ID		9212	10112
HPRD ID		05397	09292
Ensembl ID		ENSG00000178999	ENSG00000112984
Uniprot IDs		Q96GD4	B4DL79 O95235
PDB IDs		4AF3
Enriched GO Terms of Interacting Partners?		Cell Cycle Cell Division Mitotic Cell Cycle Mitotic Cell Cycle Process Cell Cycle Process Mitotic Nuclear Division Organelle Organization Chromosome Segregation Cytokinesis Regulation Of Cell Cycle Regulation Of Microtubule-based Process Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Microtubule Cytoskeleton Organization Sister Chromatid Segregation Mitotic Spindle Organization Microtubule Cytoskeleton Organization Regulation Of Cellular Component Organization Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Complex Assembly Positive Regulation Of Microtubule Plus-end Binding Regulation Of Cytoskeleton Organization Cellular Localization Protein Complex Localization Regulation Of Organelle Organization Regulation Of Signaling Regulation Of Signal Transduction Regulation Of Protein Metabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Microtubule Polymerization Or Depolymerization Microtubule-based Process Cellular Process Mitotic Sister Chromatid Segregation Positive Regulation Of Cell Cycle Regulation Of Protein Localization Protein Modification By Small Protein Conjugation Positive Regulation Of Proteolysis Positive Regulation Of Catalytic Activity Regulation Of Catalytic Activity Negative Regulation Of Wnt Signaling Pathway Regulation Of Cell Cycle Process Cytoskeleton Organization Positive Regulation Of Protein Modification Process Regulation Of Protein Kinase Activity G2/M Transition Of Mitotic Cell Cycle Mitotic Cytokinesis Negative Regulation Of Catalytic Activity Spindle Organization Negative Regulation Of Cellular Metabolic Process	Retrograde Vesicle-mediated Transport, Golgi To ER Intra-Golgi Vesicle-mediated Transport Rab Protein Signal Transduction Retrograde Transport, Endosome To Golgi Peptidyl-cysteine Methylation Histone H3-S28 Phosphorylation Minus-end-directed Organelle Transport Along Microtubule Endosomal Transport Spindle Stabilization Ras Protein Signal Transduction Abscission Golgi Vesicle Transport Cleavage Furrow Formation Mitotic Spindle Midzone Assembly Mitotic Spindle Elongation Cellular Protein Localization Protein Localization To Kinetochore Negative Regulation Of Cytokinesis Spindle Midzone Assembly Early Endosome To Golgi Transport Protein Localization To Chromosome, Centromeric Region Negative Regulation Of B Cell Apoptotic Process Attachment Of Spindle Microtubules To Kinetochore Cell Division Histone-serine Phosphorylation Regulation Of B Cell Apoptotic Process Mitotic Spindle Assembly Protein Localization To Organelle Protein Localization Protein Targeting To Golgi Establishment Of Protein Localization To Golgi Retrograde Transport, Vesicle Recycling Within Golgi Protein Localization To Chromosome Small GTPase Mediated Signal Transduction Positive Regulation Of Cytokinesis Negative Regulation Of Microtubule Depolymerization Histone Phosphorylation Cell Proliferation Protein Localization To Golgi Apparatus Cellular Localization Mitotic Spindle Organization Spindle Checkpoint Microtubule-based Process Negative Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Cytokinesis Negative Regulation Of Leukocyte Apoptotic Process Organelle Transport Along Microtubule Negative Regulation Of Protein Binding Microtubule Anchoring Cellular Response To UV
Tagcloud ?		allele birc5 cdca8 consortium contribution cpc division european exon familial fifteen fixed genotyped incenp inherited investigates meta modest passenger pivotal rs1675126 rs2071214 snp snps spite sporadic synonymous top variability	18b 20b 5b ancca atad2 bromodomain concerted coregulator deregulation drives impeded kif10 kif11 kif15 kif18a kif1a kif1c kif21 kif23 kif24 kif25 kif4a kif5a kif7 kifc1 kifc3 kinesin kinesins mll1
Tagcloud (Difference) ?		allele birc5 cdca8 consortium contribution cpc division european exon familial fifteen fixed genotyped incenp inherited investigates meta modest passenger pivotal rs1675126 rs2071214 snp snps spite sporadic synonymous top variability	18b 20b 5b ancca atad2 bromodomain concerted coregulator deregulation drives impeded kif10 kif11 kif15 kif18a kif1a kif1c kif21 kif23 kif24 kif25 kif4a kif5a kif7 kifc1 kifc3 kinesin kinesins mll1
Tagcloud (Intersection) ?