KIF20A and RAB6A

Number of citations of the paper that reports this interaction (PMID 9438855)
101

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		KIF20A	RAB6A
Gene Name		kinesin family member 20A	RAB6A, member RAS oncogene family
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Golgi Apparatus Spindle Kinesin Complex Microtubule Midbody	Golgi Membrane Golgi Apparatus Trans-Golgi Network Cytosol Membrane Cytoplasmic Vesicle Extracellular Vesicular Exosome
	Molecular Function	Microtubule Motor Activity Transporter Activity Protein Binding ATP Binding Microtubule Binding ATPase Activity Protein Kinase Binding	GTPase Activity Protein Binding GTP Binding GDP Binding Protein Domain Specific Binding Myosin V Binding
	Biological Process	Mitotic Cell Cycle Mitotic Cytokinesis Cytokinesis Cell Separation After Cytokinesis Microtubule Bundle Formation Microtubule-based Movement Metabolic Process Protein Transport Vesicle-mediated Transport	Protein Targeting To Golgi Retrograde Vesicle-mediated Transport, Golgi To ER Peptidyl-cysteine Methylation Antigen Processing And Presentation Rab Protein Signal Transduction Protein Localization To Golgi Apparatus Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Minus-end-directed Organelle Transport Along Microtubule
Pathways		Mitotic Telophase/Cytokinesis MHC class II antigen presentation Kinesins Factors involved in megakaryocyte development and platelet production Cell Cycle, Mitotic M Phase Adaptive Immune System	Pre-NOTCH Processing in Golgi Signaling by NOTCH Pre-NOTCH Expression and Processing
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		6 interactors: AURKB CDC14A FAM214B RAB6A RAB6B ZRANB2	20 interactors: BICD1 BICD2 CHM CHML DCTN1 ERC1 FKBP2 GDI1 GOLGA1 GOLGA2 GOLGA4 KIF20A OCRL PMM1 RAB7A RABAC1 RABGAP1 RABGGTB SYTL5 TMF1
Entrez ID		10112	5870
HPRD ID		09292	01543
Ensembl ID		ENSG00000112984	ENSG00000175582
Uniprot IDs		B4DL79 O95235	P20340 Q53ET8
PDB IDs			1YZQ 2GIL 3BBP 3CWZ 4DKX
Enriched GO Terms of Interacting Partners?		Retrograde Vesicle-mediated Transport, Golgi To ER Intra-Golgi Vesicle-mediated Transport Rab Protein Signal Transduction Retrograde Transport, Endosome To Golgi Peptidyl-cysteine Methylation Histone H3-S28 Phosphorylation Minus-end-directed Organelle Transport Along Microtubule Endosomal Transport Spindle Stabilization Ras Protein Signal Transduction Abscission Golgi Vesicle Transport Cleavage Furrow Formation Mitotic Spindle Midzone Assembly Mitotic Spindle Elongation Cellular Protein Localization Protein Localization To Kinetochore Negative Regulation Of Cytokinesis Spindle Midzone Assembly Early Endosome To Golgi Transport Protein Localization To Chromosome, Centromeric Region Negative Regulation Of B Cell Apoptotic Process Attachment Of Spindle Microtubules To Kinetochore Cell Division Histone-serine Phosphorylation Regulation Of B Cell Apoptotic Process Mitotic Spindle Assembly Protein Localization To Organelle Protein Localization Protein Targeting To Golgi Establishment Of Protein Localization To Golgi Retrograde Transport, Vesicle Recycling Within Golgi Protein Localization To Chromosome Small GTPase Mediated Signal Transduction Positive Regulation Of Cytokinesis Negative Regulation Of Microtubule Depolymerization Histone Phosphorylation Cell Proliferation Protein Localization To Golgi Apparatus Cellular Localization Mitotic Spindle Organization Spindle Checkpoint Microtubule-based Process Negative Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Cytokinesis Negative Regulation Of Leukocyte Apoptotic Process Organelle Transport Along Microtubule Negative Regulation Of Protein Binding Microtubule Anchoring Cellular Response To UV	Protein Geranylgeranylation Protein Localization Establishment Of Localization In Cell Intracellular Transport Cellular Localization Protein Prenylation Protein Transport Establishment Of Protein Localization Minus-end-directed Organelle Transport Along Microtubule Cellular Protein Localization Transport Retrograde Transport, Endosome To Golgi Microtubule Anchoring At Microtubule Organizing Center Intracellular Protein Transport Vesicle-mediated Transport Microtubule-based Movement Positive Regulation Of Hydrolase Activity Microtubule-based Transport Protein Targeting To Golgi Cytoskeleton-dependent Intracellular Transport Establishment Of Protein Localization To Golgi Retrograde Transport, Vesicle Recycling Within Golgi Positive Regulation Of GTPase Activity Regulation Of GTPase Activity Protein Targeting Organelle Assembly Protein Localization To Golgi Apparatus Endosomal Transport Protein Localization To Organelle Regulation Of Proteinase Activated Receptor Activity Epidermal Growth Factor Catabolic Process Negative Regulation Of Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Testosterone Secretion Positive Regulation Of Catalytic Activity Organelle Transport Along Microtubule Intra-Golgi Vesicle-mediated Transport Microtubule Anchoring Rab Protein Signal Transduction Regulation Of Catalytic Activity Luteinizing Hormone Secretion Negative Regulation Of Phospholipase C Activity Positive Regulation Of Androgen Secretion Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Establishment Of Protein Localization To Organelle Microtubule-based Process Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Phagosome-lysosome Fusion Phagosome Acidification Negative Regulation Of Protein Targeting To Membrane
Tagcloud ?		18b 20b 5b ancca atad2 bromodomain concerted coregulator deregulation drives impeded kif10 kif11 kif15 kif18a kif1a kif1c kif21 kif23 kif24 kif25 kif4a kif5a kif7 kifc1 kifc3 kinesin kinesins mll1	autosomal axonal causal coh1 cohen constitutively disability dystrophy golgi gtpase inactive integrity intellectual interfered microcephaly neurite neuritogenesis outgrowth preferentially preparations prevents q72l recessive rnai scaffold solubilization t27n vps13b
Tagcloud (Difference) ?		18b 20b 5b ancca atad2 bromodomain concerted coregulator deregulation drives impeded kif10 kif11 kif15 kif18a kif1a kif1c kif21 kif23 kif24 kif25 kif4a kif5a kif7 kifc1 kifc3 kinesin kinesins mll1	autosomal axonal causal coh1 cohen constitutively disability dystrophy golgi gtpase inactive integrity intellectual interfered microcephaly neurite neuritogenesis outgrowth preferentially preparations prevents q72l recessive rnai scaffold solubilization t27n vps13b
Tagcloud (Intersection) ?