KIF20A and RAB6A

Number of citations of the paper that reports this interaction (PubMedID 11071909)
56

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		KIF20A	RAB6A
Description		kinesin family member 20A	RAB6A, member RAS oncogene family
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Spindle Cytoskeleton Kinesin Complex Microtubule Midbody Cleavage Furrow Intercellular Bridge Mitotic Spindle	Golgi Membrane Acrosomal Membrane Nucleoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Endomembrane System Membrane Secretory Granule Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Ciliary Basal Body Extracellular Exosome Endosome To Plasma Membrane Transport Vesicle
	Molecular Function	Nucleotide Binding Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP Hydrolysis Activity Protein Kinase Binding	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity Protein Domain Specific Binding Myosin V Binding
	Biological Process	Mitotic Cytokinesis Microtubule Bundle Formation Microtubule-based Movement Protein Transport Regulation Of Cytokinesis Midbody Abscission	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Protein Transport Vesicle-mediated Transport Peptidyl-cysteine Methylation Antigen Processing And Presentation Neuron Projection Development Protein Localization To Golgi Apparatus Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Minus-end-directed Organelle Transport Along Microtubule Protein Localization To Golgi Membrane
Pathways		MHC class II antigen presentation COPI-dependent Golgi-to-ER retrograde traffic Mitotic Telophase/Cytokinesis Kinesins	Pre-NOTCH Processing in Golgi Neutrophil degranulation COPI-independent Golgi-to-ER retrograde traffic Retrograde transport at the Trans-Golgi-Network TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026)	Dimensional psychopathology (Cognitive) ( 29496196) Obesity-related traits ( 23251661)
Interacting Genes		10 interacting genes: ATOSB CDC14A LRRK1 RAB6A RAB6B RBFOX2 RYBP TFIP11 WEE2-AS1 ZRANB2	23 interacting genes: BICD1 BICD2 CHM CHML DCTN1 ERC1 FKBP2 GDI1 GOLGA1 GOLGA2 GOLGA4 GORAB KIF20A OCRL PMM1 RAB7A RABAC1 RABGAP1 RABGGTB SYTL5 TIAM1 TMEM132D TMF1
Entrez ID		10112	5870
HPRD ID		09292	01543
Ensembl ID		ENSG00000112984	ENSG00000175582
Uniprot IDs		O95235	A0A024R5J5 P20340 Q53ET8
PDB IDs		6YIP	1YZQ 2GIL 3BBP 3CWZ 4DKX 5LEF
Enriched GO Terms of Interacting Partners?		Protein Localization To Golgi Membrane Myosin V Binding Protein Localization To Golgi Apparatus Intra-Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Peptidyl-cysteine Methylation Retrograde Transport, Endosome To Golgi GTP Binding Endosome To Plasma Membrane Transport Vesicle Kinociliary Basal Body RNA Splicing Spliceosomal Complex Disassembly U2-type Post-mRNA Release Spliceosomal Complex	Small GTPase Binding Golgi Apparatus Vesicle-mediated Transport Rab-protein Geranylgeranyltransferase Complex Protein Geranylgeranylation Cellular Localization Intracellular Transport Protein Prenylation Microtubule Anchoring At Microtubule Organizing Center Protein Transport GDP-dissociation Inhibitor Activity Establishment Of Localization In Cell Establishment Of Protein Localization Microtubule Anchoring Intracellular Protein Localization Minus-end-directed Organelle Transport Along Microtubule Rab Geranylgeranyltransferase Activity GTPase Activator Activity Golgi Vesicle Transport Organelle Assembly Cytosol Trans-Golgi Network Cytoplasm Positive Regulation Of Axonogenesis Microtubule-based Movement Dynactin Binding Microtubule Cytoskeleton Organization Retrograde Transport, Endosome To Golgi Dynein Complex Binding Retromer Complex Cytoskeletal Anchor Activity Small GTPase-mediated Signal Transduction Establishment Of Organelle Localization Microtubule-based Process Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Cytosolic Transport Maintenance Of Synapse Structure Vesicle-mediated Transport To The Plasma Membrane Cytoplasmic Vesicle Mitotic Spindle Regulation Of Axonogenesis Microtubule Associated Complex Positive Regulation Of Axon Extension GTPase Binding Synaptic Vesicle Recycling Via Endosome Neuronal Cell Body Regulation Of Microtubule Cytoskeleton Organization Golgi Membrane Transport Along Microtubule Centrosome
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