TRA2A and MIRLET7A3

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		TRA2A	MIRLET7A3
Description		transformer 2 alpha homolog	microRNA let-7a-3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus	RISC Complex
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome	MiRNA-mediated Post-transcriptional Gene Silencing
Pathways
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 34021172)
Interacting Genes		82 interacting genes: C11orf58 CDK2AP2 CDK6 CRABP1 DHX15 FOXP1 LBP MAGOHB MIR1-1 MIR1-2 MIR106B MIR107 MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR199A1 MIR199A2 MIR19A MIR19B1 MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR92A1 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7G MIRLET7I NUDT21 NXF1 PPP1CC RNPS1 SELENBP1 SRSF10 TNNT1 U2SURP UBE4B XPOT YTHDC1 YWHAG	100 interacting genes: ADARB1 AIMP1 AIMP2 APOBEC3B AQR ATXN2L C1QBP CELF1 CPSF1 CPSF2 CSTF1 CSTF3 DARS1 DDX1 DDX21 DDX23 DDX3X DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ERAL1 ESRP1 FAM98A FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI1 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PDCD11 PLOD1 PRMT1 PTBP1 PUM1 PUM2 PURA PURB QARS1 RARS1 RBFOX2 RBM10 RBM12B RBM14 RBM4 RTCA RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYMPK SYNCRIP TAF15 TENT2 TRA2A TRA2B TRIM25 TRMT10C U2SURP UPF1 UTP20 YBX1 YBX3 ZFR ZNF346
Entrez ID		29896	406883
HPRD ID		04096
Ensembl ID		ENSG00000164548	ENSG00000283990
Uniprot IDs		Q13595 Q549U1
PDB IDs
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing RISC Complex Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Extracellular Vesicle MRNA Destabilization Negative Regulation Of Translation RNA Destabilization Negative Regulation Of Cytokine Production Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Cell Migration Negative Regulation Of Cell Motility Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Negative Regulation Of Locomotion Regulation Of Angiogenesis Positive Regulation Of MRNA Metabolic Process Regulation Of Gene Expression Regulation Of Vasculature Development Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Vascular Endothelial Growth Factor Production Regulation Of MRNA Metabolic Process Regulation Of MRNA Stability Regulation Of RNA Stability Regulation Of Macromolecule Metabolic Process Negative Regulation Of Developmental Process Regulation Of Cytokine Production Regulation Of Translation Negative Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Endothelial Cell Migration Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Cell Motility Extracellular Space Regulation Of Metabolic Process Regulation Of Cell Migration Regulation Of Locomotion Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Endothelial Cell Migration	RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process MRNA Metabolic Process MRNA Processing Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Splicing MRNA Binding Macromolecule Metabolic Process Post-transcriptional Regulation Of Gene Expression Regulation Of RNA Splicing Nucleoplasm Nucleus Regulation Of MRNA Metabolic Process Aminoacyl-tRNA Synthetase Multienzyme Complex Cytoplasmic Stress Granule MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Translation MiRNA Binding Ribonucleoprotein Complex Spliceosomal Complex Catalytic Step 2 Spliceosome Negative Regulation Of MRNA Metabolic Process MRNA 3'-UTR Binding Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Catabolic Process Regulation Of RNA Stability Negative Regulation Of Translation Regulation Of MRNA Stability Regulation Of Gene Expression Negative Regulation Of MRNA Catabolic Process Regulation Of Macromolecule Biosynthetic Process RNA Stabilization MRNA Stabilization Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of Gene Expression RNA 3'-end Processing TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity TRNA Metabolic Process TRNA Aminoacylation Ligase Activity Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Cytoplasmic Translation Nucleolus
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