TRA2A and XPOT

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TRA2A	XPOT
Description		transformer 2 alpha homolog	exportin for tRNA
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus	Nucleus Nuclear Pore Nucleoplasm Cytoplasm Cytosol Nuclear Matrix
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding	TRNA Binding RNA Binding Protein Binding Small GTPase Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome	TRNA Export From Nucleus Intracellular Protein Transport Nucleocytoplasmic Transport TRNA Re-export From Nucleus
Pathways			tRNA processing in the nucleus
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 34021172)	Mean corpuscular hemoglobin ( 32888494)
Interacting Genes		82 interacting genes: C11orf58 CDK2AP2 CDK6 CRABP1 DHX15 FOXP1 LBP MAGOHB MIR1-1 MIR1-2 MIR106B MIR107 MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR199A1 MIR199A2 MIR19A MIR19B1 MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR92A1 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7G MIRLET7I NUDT21 NXF1 PPP1CC RNPS1 SELENBP1 SRSF10 TNNT1 U2SURP UBE4B XPOT YTHDC1 YWHAG	13 interacting genes: CEBPA FILNC1 HDLBP HSPA13 KRT75 NUP153 NUP214 POU6F2 RAN RANBP2 RNF10 TRA2A XPO7
Entrez ID		29896	11260
HPRD ID		04096	04418
Ensembl ID		ENSG00000164548	ENSG00000184575
Uniprot IDs		Q13595 Q549U1	O43592
PDB IDs
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing RISC Complex Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Extracellular Vesicle MRNA Destabilization Negative Regulation Of Translation RNA Destabilization Negative Regulation Of Cytokine Production Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Cell Migration Negative Regulation Of Cell Motility Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Negative Regulation Of Locomotion Regulation Of Angiogenesis Positive Regulation Of MRNA Metabolic Process Regulation Of Gene Expression Regulation Of Vasculature Development Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Vascular Endothelial Growth Factor Production Regulation Of MRNA Metabolic Process Regulation Of MRNA Stability Regulation Of RNA Stability Regulation Of Macromolecule Metabolic Process Negative Regulation Of Developmental Process Regulation Of Cytokine Production Regulation Of Translation Negative Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Endothelial Cell Migration Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Cell Motility Extracellular Space Regulation Of Metabolic Process Regulation Of Cell Migration Regulation Of Locomotion Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Endothelial Cell Migration	Nuclear Pore Nuclear Export Nuclear Export Signal Receptor Activity Nuclear Transport Nucleocytoplasmic Transport Regulation Of Nucleocytoplasmic Transport Import Into Nucleus Protein Export From Nucleus Protein Import Into Nucleus RNA Transport Negative Regulation Of RNA Export From Nucleus Protein Localization To Nucleus Nucleobase-containing Compound Transport Nuclear Envelope RNA Export From Nucleus Intracellular Protein Transport Nuclear Inclusion Body Regulation Of Intracellular Transport Nuclear Pore Nuclear Basket Regulation Of RNA Export From Nucleus Establishment Of Protein Localization To Organelle MRNA Transport Structural Constituent Of Nuclear Pore Nuclear Localization Sequence Binding Regulation Of Cellular Localization Nucleus RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Cytoplasmic Side Of Nuclear Pore Protein Transport Negative Regulation Of Intracellular Transport Protein Localization To Organelle Intracellular Transport Response To Vitamin B2 C/EBP Complex RNA Nuclear Export Complex SnRNA Import Into Nucleus Pre-miRNA Export From Nucleus Cytoplasmic Periphery Of The Nuclear Pore Complex Establishment Of Protein Localization Protein-containing Complex Binding CHOP-C/EBP Complex White Fat Cell Proliferation RNA Import Into Nucleus SUMO Ligase Complex Nuclear Pore Cytoplasmic Filaments Viral Penetration Into Host Nucleus Cholesterol Metabolic Process Sterol Metabolic Process Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex
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