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USP10 and SCNN1G
Number of citations of the paper that reports this interaction (PubMedID
18632802
)
0
Data Source:
HPRD
(in vivo)
USP10
SCNN1G
Description
ubiquitin specific peptidase 10
sodium channel epithelial 1 subunit gamma
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Endosome
Early Endosome
Cytosol
Cytosolic Ribosome
Protein-containing Complex
Intermediate Filament Cytoskeleton
Nucleoplasm
Plasma Membrane
External Side Of Plasma Membrane
Membrane
Apical Plasma Membrane
Sodium Channel Complex
Extracellular Exosome
Molecular Function
P53 Binding
RNA Binding
Cysteine-type Endopeptidase Activity
Cysteine-type Deubiquitinase Activity
Protein Binding
Peptidase Activity
Cysteine-type Peptidase Activity
Hydrolase Activity
Transmembrane Transporter Binding
Molecular Function Inhibitor Activity
Monoatomic Ion Channel Activity
Sodium Channel Activity
Protein Binding
Ligand-gated Sodium Channel Activity
WW Domain Binding
Biological Process
DNA Repair
Chromatin Remodeling
Proteolysis
Protein Monoubiquitination
Autophagy
DNA Damage Response
Regulation Of Autophagy
Protein Deubiquitination
Translesion Synthesis
DNA Damage Response, Signal Transduction By P53 Class Mediator
Regulation Of Protein Stability
Stress Granule Assembly
Monoubiquitinated Protein Deubiquitination
Negative Regulation Of Canonical NF-kappaB Signal Transduction
Negative Regulation Of Stress Granule Assembly
Cellular Response To Interleukin-1
Rescue Of Stalled Ribosome
Ribosome-associated Ubiquitin-dependent Protein Catabolic Process
Monoatomic Ion Transport
Sodium Ion Transport
Intracellular Sodium Ion Homeostasis
Regulation Of Blood Pressure
Monoatomic Ion Transmembrane Transport
Sodium Ion Transmembrane Transport
Multicellular Organismal-level Water Homeostasis
Sensory Perception Of Salty Taste
Sensory Perception Of Sour Taste
Sodium Ion Homeostasis
Cellular Response To Acidic PH
Sodium Ion Import Across Plasma Membrane
Cellular Response To Aldosterone
Cellular Response To Vasopressin
Pathways
Termination of translesion DNA synthesis
Ub-specific processing proteases
Stimuli-sensing channels
Sensory perception of salty taste
Drugs
Triamterene
Amiloride
Diseases
Liddle syndrome
Bronchiectasis with or without elevated sweat chloride
Hyperkalemic distal renal tubular acidosis (RTA type 4), including the following two diseases: Pseudohypoaldosteronism type I (PHA1); Pseudohypoaldosteronism type II (Gordon's syndrome)
GWAS
Appendicular lean mass (
33097823
)
Copper levels (
26025379
)
Height (
18391951
)
High light scatter reticulocyte count (
27863252
32888494
)
High light scatter reticulocyte percentage of red cells (
27863252
32888494
)
Immature fraction of reticulocytes (
32888494
)
Plasma factor VII activating protease levels (
30070759
)
Response to mTOR inhibitor (everolimus) (
24009623
)
Reticulocyte count (
27863252
32888494
)
Reticulocyte fraction of red cells (
27863252
32888494
)
Heel bone mineral density (
30598549
)
Parent of origin effect on receptive language ability (paternal) (
32635940
)
Interacting Genes
32 interacting genes:
AKT1
ANLN
AR
AXIN1
CCND3
CFTR
CTNNB1
DAAM1
FSCN1
FZR1
G3BP1
G3BP2
H2AC20
HDAC6
HNRNPLL
KLF4
LINC00460
MAP1LC3B
MSH2
NOTCH1
PABPC1
PCGF5
RAD51
RUNX1
SCNN1A
SCNN1G
SMAD4
SNX3
SOX21-AS1
TRNAU1AP
UBC
ZBTB7A
13 interacting genes:
COMMD10
EPN1
MAPK1
NEDD4
NEDD4L
SCNN1A
SCNN1B
SCNN1D
SERP1
SOX4
STX1A
USP10
WWP2
Entrez ID
9100
6340
HPRD ID
07029
02862
Ensembl ID
ENSG00000103194
ENSG00000166828
Uniprot IDs
A0A7G6J4N4
Q14694
A5X2V1
P51170
PDB IDs
7XHF
8TH6
6BQN
6WTH
9BLR
9BTG
9BTU
Enriched GO Terms of Interacting Partners
?
Transcription Corepressor Binding
Positive Regulation Of Cellular Component Organization
Enzyme Binding
Response To Alcohol
Epithelial Cell Differentiation Involved In Prostate Gland Development
Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
SMAD Binding
Cellular Response To Oxygen-containing Compound
Cellular Response To Hormone Stimulus
Response To Ketone
Negative Regulation Of Macromolecule Metabolic Process
I-SMAD Binding
Negative Regulation Of RNA Metabolic Process
In Utero Embryonic Development
Negative Regulation Of Canonical Wnt Signaling Pathway
Regulation Of Cell Proliferation Involved In Heart Morphogenesis
Chordate Embryonic Development
Positive Regulation Of Gene Expression
Epithelial Cell Differentiation
Regulation Of Extracellular Matrix Organization
Negative Regulation Of Metabolic Process
Response To Lipid
Embryo Development Ending In Birth Or Egg Hatching
Multicellular Organism Development
Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development
Axis Specification
Regulation Of Cell Cycle Phase Transition
Negative Regulation Of Macromolecule Biosynthetic Process
Cytosol
Negative Regulation Of Wnt Signaling Pathway
Positive Regulation Of Extracellular Matrix Organization
Cell Cortex
Positive Regulation Of Anaphase-promoting Complex-dependent Catabolic Process
Multicellular Organismal-level Water Homeostasis
Sensory Perception Of Salty Taste
Negative Regulation Of Biosynthetic Process
Regulation Of Wnt Signaling Pathway
Positive Regulation Of Organelle Assembly
Positive Regulation Of Epithelial Cell Proliferation
Regulation Of Mitotic Cell Cycle
Endocardial Cell Differentiation
Positive Regulation Of Cellular Component Biogenesis
Beta-catenin Binding
Response To Mineralocorticoid
Regulation Of Cell Cycle Process
Regulation Of Anaphase-promoting Complex-dependent Catabolic Process
Regulation Of Protein Metabolic Process
Regulation Of Cellular Component Organization
Protein-containing Complex
Import Into Cell
Sodium Ion Import Across Plasma Membrane
Sensory Perception Of Salty Taste
Negative Regulation Of Potassium Ion Export Across Plasma Membrane
Cellular Response To Aldosterone
Sodium Channel Complex
Sensory Perception Of Sour Taste
Cellular Response To Vasopressin
Transmembrane Transporter Binding
Potassium Channel Inhibitor Activity
Regulation Of Biological Quality
Regulation Of Potassium Ion Export Across Plasma Membrane
Cellular Response To Mineralocorticoid Stimulus
Ligand-gated Sodium Channel Activity
Sodium Ion Transport
Response To Aldosterone
Cellular Response To Acidic PH
Negative Regulation Of Potassium Ion Transmembrane Transport
Intracellular Sodium Ion Homeostasis
Inorganic Cation Import Across Plasma Membrane
Response To Acidic PH
Cellular Response To PH
Negative Regulation Of Potassium Ion Transport
Sensory Perception Of Taste
Sodium Channel Activity
Sodium Ion Transmembrane Transport
Sodium Ion Homeostasis
Response To Mineralocorticoid
Response To PH
Import Across Plasma Membrane
Protein Monoubiquitination
Endocytosis
Sodium Channel Inhibitor Activity
Regulation Of Potassium Ion Transmembrane Transport
Cellular Response To Corticosteroid Stimulus
Negative Regulation Of Cation Transmembrane Transport
Negative Regulation Of Monoatomic Ion Transmembrane Transport
Intracellular Chemical Homeostasis
Cellular Response To Steroid Hormone Stimulus
Regulation Of Potassium Ion Transport
Negative Regulation Of Sodium Ion Transport
Metal Ion Transport
Negative Regulation Of Monoatomic Ion Transport
Regulation Of Transport
Protein Modification Process
Sensory Perception Of Chemical Stimulus
Cellular Homeostasis
Negative Regulation Of Transmembrane Transport
Receptor Catabolic Process
Protein Modification By Small Protein Conjugation
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Tagcloud (Difference)
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Tagcloud (Intersection)
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