SCNN1G and SERP1

Number of citations of the paper that reports this interaction (PMID 22526458)
0

Data Source:
BioGRID (protein complementation assay)

		SCNN1G	SERP1
Gene Name		sodium channel, non voltage gated 1 gamma subunit	stress-associated endoplasmic reticulum protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Apical Plasma Membrane Sodium Channel Complex Extracellular Vesicular Exosome	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Ribosome Cytoplasmic Microtubule Integral Component Of Membrane
	Molecular Function	Sodium Channel Activity Protein Binding Ligand-gated Sodium Channel Activity WW Domain Binding
	Biological Process	Sodium Ion Transport Excretion Ion Transmembrane Transport Sodium Ion Transmembrane Transport Multicellular Organismal Water Homeostasis Response To Stimulus Sensory Perception Of Taste Sodium Ion Homeostasis Transmembrane Transport	Skeletal System Development Glucose Metabolic Process Cellular Protein Modification Process Protein Glycosylation Response To Stress Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Plasma Membrane Organization Post-embryonic Development Multicellular Organismal Aging Protein Transport Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Insulin Secretion Cellular Protein Metabolic Process Positive Regulation Of Translation Positive Regulation Of Organ Growth Muscle Organ Morphogenesis Positive Regulation Of Growth Hormone Secretion
Pathways		Ion channel transport Stimuli-sensing channels	IRE1alpha activates chaperones XBP1(S) activates chaperone genes Unfolded Protein Response (UPR)
Drugs		Triamterene Amiloride
Diseases
GWAS
Protein-Protein Interactions		11 interactors: EPN1 MAPK1 NEDD4 NEDD4L SCNN1A SCNN1B SCNN1D SERP1 STX1A USP10 WWP2	7 interactors: APP CANX SCNN1A SCNN1G SEC61A1 SEC61B TMEM79
Entrez ID		6340	27230
HPRD ID		02862	18037
Ensembl ID		ENSG00000166828	ENSG00000120742
Uniprot IDs		A5X2V1 P51170	Q9Y6X1
PDB IDs
Enriched GO Terms of Interacting Partners?		Sodium Ion Homeostasis Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Potassium Ion Transmembrane Transport Excretion Regulation Of Potassium Ion Transport Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Water Homeostasis Sensory Perception Of Taste Sodium Ion Transport Regulation Of Membrane Potential Negative Regulation Of Sodium Ion Transport Transport Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Ubiquitin-dependent Protein Catabolic Process Regulation Of Cellular Localization Protein Polyubiquitination Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Viral Process Cellular Protein Catabolic Process Sodium Ion Transmembrane Transport Protein K63-linked Ubiquitination Protein Catabolic Process Negative Regulation Of Transporter Activity Protein Monoubiquitination Monovalent Inorganic Cation Transport Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Response To Stimulus Proteasomal Protein Catabolic Process Multicellular Organismal Water Homeostasis Positive Regulation Of Transport Regulation Of Protein Localization Sensory Perception Metal Ion Transport Regulation Of Sodium Ion Transport Cellular Macromolecule Catabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Transmission Of Virus Development Involved In Symbiotic Interaction Positive Regulation Of Translation Regulation Of Vesicle-mediated Transport Regulation Of Protein Catabolic Process Negative Regulation Of Transport Ion Transport Sensory Perception Of Chemical Stimulus Regulation Of Ion Transmembrane Transport Negative Regulation Of Ion Transport MAPK Import Into Nucleus	Multicellular Organismal Water Homeostasis Water Homeostasis Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Regulation Of Body Fluid Levels Transport Sodium Ion Homeostasis Antigen Processing And Presentation Of Peptide Antigen Chemical Homeostasis Antigen Processing And Presentation Excretion Establishment Of Localization In Cell Sensory Perception Of Taste Cellular Localization Metal Ion Homeostasis Secretion By Cell SRP-dependent Cotranslational Protein Targeting To Membrane Homeostatic Process Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Ion Homeostasis Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Protein Localization To Endoplasmic Reticulum Synaptic Growth At Neuromuscular Junction Secretion Cell Maturation Cell Growth Collateral Sprouting In Absence Of Injury Cuticle Development Protein Targeting To Membrane Cornification Collateral Sprouting Axon Midline Choice Point Recognition Retrograde Protein Transport, ER To Cytosol Sodium Ion Transmembrane Transport Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Immune System Process Axon Choice Point Recognition Establishment Of Protein Localization To Membrane Posttranslational Protein Targeting To Membrane Sodium Ion Transport Neuron Remodeling Neurological System Process Exocytosis Establishment Of Protein Localization To Organelle Protein Localization To Membrane Establishment Of Skin Barrier Cellular Copper Ion Homeostasis Regulation Of Water Loss Via Skin
Tagcloud ?		adherens aqp2 aqp3 bioinformatic collecting crebbp ctnnb1 duct elf3 enacbeta enacgamma esbl flanking gatad2b gov helixweb hmbox1 http hypotheses isotope junb junctions mnpd mpkccd nih pser552 rangap1 vasopressin
Tagcloud (Difference) ?		adherens aqp2 aqp3 bioinformatic collecting crebbp ctnnb1 duct elf3 enacbeta enacgamma esbl flanking gatad2b gov helixweb hmbox1 http hypotheses isotope junb junctions mnpd mpkccd nih pser552 rangap1 vasopressin
Tagcloud (Intersection) ?