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SCNN1G and EPN1
Number of citations of the paper that reports this interaction (PMID
16574660
)
30
Data Source:
BioGRID
(pull down)
SCNN1G
EPN1
Gene Name
sodium channel, non voltage gated 1 gamma subunit
epsin 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
External Side Of Plasma Membrane
Apical Plasma Membrane
Sodium Channel Complex
Extracellular Vesicular Exosome
Nucleus
Cytoplasm
Plasma Membrane
Coated Pit
Molecular Function
Sodium Channel Activity
Protein Binding
Ligand-gated Sodium Channel Activity
WW Domain Binding
Transcription Factor Binding
Lipid Binding
Biological Process
Sodium Ion Transport
Excretion
Ion Transmembrane Transport
Sodium Ion Transmembrane Transport
Multicellular Organismal Water Homeostasis
Response To Stimulus
Sensory Perception Of Taste
Sodium Ion Homeostasis
Transmembrane Transport
In Utero Embryonic Development
Endocytosis
Epidermal Growth Factor Receptor Signaling Pathway
Notch Signaling Pathway
Female Pregnancy
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Embryonic Organ Development
Pathways
Ion channel transport
Stimuli-sensing channels
Signaling by EGFR
EGFR downregulation
Signaling by EGFR in Cancer
Signaling by Ligand-Responsive EGFR Variants in Cancer
Signaling by Overexpressed Wild-Type EGFR in Cancer
Signaling by EGFRvIII in Cancer
Drugs
Triamterene
Amiloride
Diseases
GWAS
Major depressive disorder (
23377640
)
Protein-Protein Interactions
11 interactors:
EPN1
MAPK1
NEDD4
NEDD4L
SCNN1A
SCNN1B
SCNN1D
SERP1
STX1A
USP10
WWP2
20 interactors:
AP2A1
AP2A2
CDK1
CLTC
CRMP1
DAZAP2
EPS15
EPS15L1
FBXO25
KIAA1377
LAPTM5
MED31
PLEKHB2
REPS2
RNF11
SCNN1A
SCNN1B
SCNN1G
UBC
ZBTB16
Entrez ID
6340
29924
HPRD ID
02862
06270
Ensembl ID
ENSG00000166828
ENSG00000063245
Uniprot IDs
A5X2V1
P51170
Q9Y6I3
PDB IDs
1INZ
Enriched GO Terms of Interacting Partners
?
Sodium Ion Homeostasis
Regulation Of Potassium Ion Transmembrane Transporter Activity
Regulation Of Potassium Ion Transmembrane Transport
Excretion
Regulation Of Potassium Ion Transport
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Water Homeostasis
Sensory Perception Of Taste
Sodium Ion Transport
Regulation Of Membrane Potential
Negative Regulation Of Sodium Ion Transport
Transport
Regulation Of Ion Transmembrane Transporter Activity
Regulation Of Transmembrane Transporter Activity
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Ubiquitin-dependent Protein Catabolic Process
Regulation Of Cellular Localization
Protein Polyubiquitination
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Viral Process
Cellular Protein Catabolic Process
Sodium Ion Transmembrane Transport
Protein K63-linked Ubiquitination
Protein Catabolic Process
Negative Regulation Of Transporter Activity
Protein Monoubiquitination
Monovalent Inorganic Cation Transport
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Response To Stimulus
Proteasomal Protein Catabolic Process
Multicellular Organismal Water Homeostasis
Positive Regulation Of Transport
Regulation Of Protein Localization
Sensory Perception
Metal Ion Transport
Regulation Of Sodium Ion Transport
Cellular Macromolecule Catabolic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage
Transmission Of Virus
Development Involved In Symbiotic Interaction
Positive Regulation Of Translation
Regulation Of Vesicle-mediated Transport
Regulation Of Protein Catabolic Process
Negative Regulation Of Transport
Ion Transport
Sensory Perception Of Chemical Stimulus
Regulation Of Ion Transmembrane Transport
Negative Regulation Of Ion Transport
MAPK Import Into Nucleus
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of ERBB Signaling Pathway
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of ERBB Signaling Pathway
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Sodium Ion Homeostasis
Negative Regulation Of Hyaluronan Biosynthetic Process
Enzyme Linked Receptor Protein Signaling Pathway
Excretion
Multicellular Organismal Water Homeostasis
Water Homeostasis
Sensory Perception Of Taste
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Antigen Processing And Presentation Of Peptide Antigen
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Post-Golgi Vesicle-mediated Transport
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II
Antigen Processing And Presentation
Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II
Golgi To Endosome Transport
Endocytosis
Regulation Of Defense Response To Virus By Virus
Axon Guidance
Cell Projection Morphogenesis
Cell Part Morphogenesis
Clathrin-mediated Endocytosis
Sodium Ion Transmembrane Transport
Endosomal Transport
Axonogenesis
Axon Development
Toll-like Receptor 5 Signaling Pathway
Protein Ubiquitination
Toll-like Receptor 10 Signaling Pathway
Cellular Response To Growth Factor Stimulus
Pronuclear Fusion
Sodium Ion Transport
Cell Morphogenesis Involved In Neuron Differentiation
Cell Morphogenesis
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Chemotaxis
Response To Growth Factor
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Toll-like Receptor 2 Signaling Pathway
Protein Modification By Small Protein Conjugation
Golgi Vesicle Transport
Toll-like Receptor 9 Signaling Pathway
Tagcloud
?
adherens
aqp2
aqp3
bioinformatic
collecting
crebbp
ctnnb1
duct
elf3
enacbeta
enacgamma
esbl
flanking
gatad2b
gov
helixweb
hmbox1
http
hypotheses
isotope
junb
junctions
mnpd
mpkccd
nih
pser552
rangap1
vasopressin
Tagcloud (Difference)
?
adherens
aqp2
aqp3
bioinformatic
collecting
crebbp
ctnnb1
duct
elf3
enacbeta
enacgamma
esbl
flanking
gatad2b
gov
helixweb
hmbox1
http
hypotheses
isotope
junb
junctions
mnpd
mpkccd
nih
pser552
rangap1
vasopressin
Tagcloud (Intersection)
?