SCNN1G and SCNN1D

Number of citations of the paper that reports this interaction (PubMedID 7499195)
0

Data Source:
HPRD (in vivo)

		SCNN1G	SCNN1D
Description		sodium channel epithelial 1 subunit gamma	sodium channel epithelial 1 subunit delta
Image
GO Annotations	Cellular Component	Nucleoplasm Plasma Membrane External Side Of Plasma Membrane Membrane Apical Plasma Membrane Sodium Channel Complex Extracellular Exosome	Plasma Membrane Actin Cytoskeleton Membrane Apical Plasma Membrane Sodium Channel Complex
	Molecular Function	Monoatomic Ion Channel Activity Sodium Channel Activity Protein Binding Ligand-gated Sodium Channel Activity WW Domain Binding	Sodium Channel Activity Protein Binding Ligand-gated Sodium Channel Activity
	Biological Process	Monoatomic Ion Transport Sodium Ion Transport Intracellular Sodium Ion Homeostasis Regulation Of Blood Pressure Monoatomic Ion Transmembrane Transport Sodium Ion Transmembrane Transport Multicellular Organismal-level Water Homeostasis Sensory Perception Of Salty Taste Sensory Perception Of Sour Taste Sodium Ion Homeostasis Cellular Response To Acidic PH Sodium Ion Import Across Plasma Membrane Cellular Response To Aldosterone Cellular Response To Vasopressin	Monoatomic Ion Transport Sodium Ion Transport Intracellular Sodium Ion Homeostasis Regulation Of Blood Pressure Monoatomic Ion Transmembrane Transport Sodium Ion Transmembrane Transport Sensory Perception Of Salty Taste Sensory Perception Of Sour Taste Cellular Response To Acidic PH Sodium Ion Import Across Plasma Membrane Cellular Response To Aldosterone Cellular Response To Vasopressin
Pathways		Stimuli-sensing channels Sensory perception of salty taste	Stimuli-sensing channels Sensory perception of salty taste
Drugs		Triamterene Amiloride	Triamterene Amiloride
Diseases		Liddle syndrome Bronchiectasis with or without elevated sweat chloride Hyperkalemic distal renal tubular acidosis (RTA type 4), including the following two diseases: Pseudohypoaldosteronism type I (PHA1); Pseudohypoaldosteronism type II (Gordon's syndrome)
GWAS		Heel bone mineral density ( 30598549) Parent of origin effect on receptive language ability (paternal) ( 32635940)	Inflammatory bowel disease ( 28067908) Platelet count ( 24777453) Ulcerative colitis ( 28067908)
Interacting Genes		13 interacting genes: COMMD10 EPN1 MAPK1 NEDD4 NEDD4L SCNN1A SCNN1B SCNN1D SERP1 SOX4 STX1A USP10 WWP2	2 interacting genes: SCNN1B SCNN1G
Entrez ID		6340	6339
HPRD ID		02862	03209
Ensembl ID		ENSG00000166828	ENSG00000162572
Uniprot IDs		A5X2V1 P51170	P51172
PDB IDs		6BQN 6WTH 9BLR 9BTG 9BTU	9BLR
Enriched GO Terms of Interacting Partners?		Import Into Cell Sodium Ion Import Across Plasma Membrane Sensory Perception Of Salty Taste Negative Regulation Of Potassium Ion Export Across Plasma Membrane Cellular Response To Aldosterone Sodium Channel Complex Sensory Perception Of Sour Taste Cellular Response To Vasopressin Transmembrane Transporter Binding Potassium Channel Inhibitor Activity Regulation Of Biological Quality Regulation Of Potassium Ion Export Across Plasma Membrane Cellular Response To Mineralocorticoid Stimulus Ligand-gated Sodium Channel Activity Sodium Ion Transport Response To Aldosterone Cellular Response To Acidic PH Negative Regulation Of Potassium Ion Transmembrane Transport Intracellular Sodium Ion Homeostasis Inorganic Cation Import Across Plasma Membrane Response To Acidic PH Cellular Response To PH Negative Regulation Of Potassium Ion Transport Sensory Perception Of Taste Sodium Channel Activity Sodium Ion Transmembrane Transport Sodium Ion Homeostasis Response To Mineralocorticoid Response To PH Import Across Plasma Membrane Protein Monoubiquitination Endocytosis Sodium Channel Inhibitor Activity Regulation Of Potassium Ion Transmembrane Transport Cellular Response To Corticosteroid Stimulus Negative Regulation Of Cation Transmembrane Transport Negative Regulation Of Monoatomic Ion Transmembrane Transport Intracellular Chemical Homeostasis Cellular Response To Steroid Hormone Stimulus Regulation Of Potassium Ion Transport Negative Regulation Of Sodium Ion Transport Metal Ion Transport Negative Regulation Of Monoatomic Ion Transport Regulation Of Transport Protein Modification Process Sensory Perception Of Chemical Stimulus Cellular Homeostasis Negative Regulation Of Transmembrane Transport Receptor Catabolic Process Protein Modification By Small Protein Conjugation	Sensory Perception Of Sour Taste Cellular Response To Vasopressin Sensory Perception Of Salty Taste Cellular Response To Aldosterone Sodium Channel Complex Cellular Response To Mineralocorticoid Stimulus Ligand-gated Sodium Channel Activity Response To Aldosterone Cellular Response To Acidic PH Intracellular Sodium Ion Homeostasis Sodium Ion Import Across Plasma Membrane WW Domain Binding Response To Acidic PH Cellular Response To PH Multicellular Organismal-level Water Homeostasis Sensory Perception Of Taste Sodium Channel Activity Sodium Ion Homeostasis Response To Mineralocorticoid Response To PH Cellular Response To Corticosteroid Stimulus Multicellular Organismal-level Chemical Homeostasis Cellular Response To Steroid Hormone Stimulus Inorganic Cation Import Across Plasma Membrane Sensory Perception Of Chemical Stimulus Sodium Ion Transmembrane Transport Import Across Plasma Membrane Response To Corticosteroid Regulation Of Blood Pressure Cellular Response To Peptide Hormone Stimulus Sodium Ion Transport Response To Steroid Hormone Response To Ketone Response To Alcohol Regulation Of Body Fluid Levels Response To Peptide Hormone Cellular Response To Hormone Stimulus External Side Of Plasma Membrane Apical Plasma Membrane Intracellular Monoatomic Cation Homeostasis Aldosterone Metabolic Process Intracellular Monoatomic Ion Homeostasis Inorganic Ion Homeostasis Cellular Response To Lipid Sensory Perception Monoatomic Ion Homeostasis Monoatomic Cation Homeostasis Multicellular Organismal-level Homeostasis Intracellular Chemical Homeostasis Tonic Smooth Muscle Contraction
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