SCNN1G and SCNN1B

Number of citations of the paper that reports this interaction (PMID 8986818)
86

Data Source:
HPRD (in vivo)

		SCNN1G	SCNN1B
Gene Name		sodium channel, non voltage gated 1 gamma subunit	sodium channel, non voltage gated 1 beta subunit
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Apical Plasma Membrane Sodium Channel Complex Extracellular Vesicular Exosome	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Apical Plasma Membrane Sodium Channel Complex Extracellular Vesicular Exosome
	Molecular Function	Sodium Channel Activity Protein Binding Ligand-gated Sodium Channel Activity WW Domain Binding	Protein Binding Ligand-gated Sodium Channel Activity WW Domain Binding
	Biological Process	Sodium Ion Transport Excretion Ion Transmembrane Transport Sodium Ion Transmembrane Transport Multicellular Organismal Water Homeostasis Response To Stimulus Sensory Perception Of Taste Sodium Ion Homeostasis Transmembrane Transport	Sodium Ion Transport Excretion Ion Transmembrane Transport Sodium Ion Transmembrane Transport Multicellular Organismal Water Homeostasis Response To Stimulus Sensory Perception Of Taste Sodium Ion Homeostasis Transmembrane Transport
Pathways		Ion channel transport Stimuli-sensing channels	Ion channel transport Stimuli-sensing channels
Drugs		Triamterene Amiloride	Triamterene Amiloride
Diseases
GWAS
Protein-Protein Interactions		11 interactors: EPN1 MAPK1 NEDD4 NEDD4L SCNN1A SCNN1B SCNN1D SERP1 STX1A USP10 WWP2	13 interactors: ANK3 CNTN1 EPN1 HECW1 ITCH NEDD4 NEDD4L NFASC SCNN1A SCNN1D SCNN1G STX1A WWP2
Entrez ID		6340	6338
HPRD ID		02862	02861
Ensembl ID		ENSG00000166828	ENSG00000168447
Uniprot IDs		A5X2V1 P51170	B2R812 P51168
PDB IDs
Enriched GO Terms of Interacting Partners?		Sodium Ion Homeostasis Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Potassium Ion Transmembrane Transport Excretion Regulation Of Potassium Ion Transport Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Water Homeostasis Sensory Perception Of Taste Sodium Ion Transport Regulation Of Membrane Potential Negative Regulation Of Sodium Ion Transport Transport Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Ubiquitin-dependent Protein Catabolic Process Regulation Of Cellular Localization Protein Polyubiquitination Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Viral Process Cellular Protein Catabolic Process Sodium Ion Transmembrane Transport Protein K63-linked Ubiquitination Protein Catabolic Process Negative Regulation Of Transporter Activity Protein Monoubiquitination Monovalent Inorganic Cation Transport Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Response To Stimulus Proteasomal Protein Catabolic Process Multicellular Organismal Water Homeostasis Positive Regulation Of Transport Regulation Of Protein Localization Sensory Perception Metal Ion Transport Regulation Of Sodium Ion Transport Cellular Macromolecule Catabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Transmission Of Virus Development Involved In Symbiotic Interaction Positive Regulation Of Translation Regulation Of Vesicle-mediated Transport Regulation Of Protein Catabolic Process Negative Regulation Of Transport Ion Transport Sensory Perception Of Chemical Stimulus Regulation Of Ion Transmembrane Transport Negative Regulation Of Ion Transport MAPK Import Into Nucleus	Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Transport Regulation Of Sodium Ion Transport Regulation Of Membrane Potential Sodium Ion Homeostasis Protein K63-linked Ubiquitination Positive Regulation Of Sodium Ion Transport Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Negative Regulation Of Transporter Activity Protein Polyubiquitination Excretion Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Water Homeostasis Sensory Perception Of Taste Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Sodium Ion Transport Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Catabolic Process Regulation Of Ion Transport Negative Regulation Of Sodium Ion Transport Negative Regulation Of Ion Transport Negative Regulation Of Potassium Ion Transmembrane Transport Interaction With Host Locomotion Positive Regulation Of Transport Negative Regulation Of Transport Notch Signaling Pathway Negative Regulation Of Potassium Ion Transport Cellular Macromolecule Catabolic Process Regulation Of Ion Transmembrane Transport Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Synapse Organization Metal Ion Homeostasis Regulation Of Sodium Ion Transmembrane Transporter Activity Viral Life Cycle Positive Regulation Of Ion Transport Sodium Ion Transmembrane Transport Viral Process Regulation Of Membrane Depolarization Regulation Of Sodium Ion Transmembrane Transport Negative Regulation Of Signal Transduction Ion Homeostasis Protein K48-linked Ubiquitination
Tagcloud ?		adherens aqp2 aqp3 bioinformatic collecting crebbp ctnnb1 duct elf3 enacbeta enacgamma esbl flanking gatad2b gov helixweb hmbox1 http hypotheses isotope junb junctions mnpd mpkccd nih pser552 rangap1 vasopressin	aldosterone atp1a1 atpasealpha1 betamethasone breaths compliance corticosteroid corticosteroids elastin enac enacalpha enacbeta epithelia fetuses gestation gr inflation infused infusions intravenously mineralocorticoid mr ovine pressures reabsorption stepwise synergy transcriptomic
Tagcloud (Difference) ?		adherens aqp2 aqp3 bioinformatic collecting crebbp ctnnb1 duct elf3 enacgamma esbl flanking gatad2b gov helixweb hmbox1 http hypotheses isotope junb junctions mnpd mpkccd nih pser552 rangap1 vasopressin	aldosterone atp1a1 atpasealpha1 betamethasone breaths compliance corticosteroid corticosteroids elastin enac enacalpha epithelia fetuses gestation gr inflation infused infusions intravenously mineralocorticoid mr ovine pressures reabsorption stepwise synergy transcriptomic
Tagcloud (Intersection) ?		enacbeta