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CCNH and CALCOCO2
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
56
Data Source:
BioGRID
(two hybrid)
CCNH
CALCOCO2
Description
cyclin H
calcium binding and coiled-coil domain 2
Image
GO Annotations
Cellular Component
Cyclin-dependent Protein Kinase Holoenzyme Complex
Transcription Factor TFIIH Core Complex
Male Germ Cell Nucleus
Nucleus
Nucleoplasm
Transcription Factor TFIIH Holo Complex
CAK-ERCC2 Complex
Transcription Factor TFIIK Complex
Autophagosome Membrane
Nucleus
Cytoplasm
Autophagosome
Cytosol
Cytoskeleton
Membrane
PML Body
Cytoplasmic Vesicle
Perinuclear Region Of Cytoplasm
Molecular Function
Protein Binding
RNA Polymerase II General Transcription Initiation Factor Activity
Kinase Activity
Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity
Protein Binding
Zinc Ion Binding
Protein Homodimerization Activity
Metal Ion Binding
Biological Process
DNA-templated Transcription
Regulation Of Transcription By RNA Polymerase II
Transcription Initiation At RNA Polymerase II Promoter
Protein Stabilization
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Autophagy
Viral Process
Response To Type II Interferon
Xenophagy
Positive Regulation Of Autophagosome Maturation
Pathways
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
Formation of HIV-1 elongation complex containing HIV-1 Tat
Tat-mediated elongation of the HIV-1 transcript
NoRC negatively regulates rRNA expression
Formation of Incision Complex in GG-NER
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
Cyclin E associated events during G1/S transition
Cyclin D associated events in G1
Cyclin A/B1/B2 associated events during G2/M transition
Cyclin A:Cdk2-associated events at S phase entry
mRNA Capping
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase I Transcription Termination
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Drugs
Diseases
GWAS
Adult body size (
32376654
)
Bipolar disorder lithium response (continuous) or schizophrenia (
29121268
)
Diastolic blood pressure (
27841878
)
Fasting glucose (
34074324
)
Initial pursuit acceleration (
29064472
)
Macular thickness (
30535121
)
Major depressive disorder (
23377640
)
Prostate cancer aggressiveness (
25939597
)
Pulse pressure (
27841878
)
Systolic blood pressure (
27841878
)
Appendicular lean mass (
33097823
)
Blood protein levels (
30072576
)
Chronotype (
30696823
)
Liver enzyme levels (alkaline phosphatase) (
33972514
)
Serum alkaline phosphatase levels (
33547301
)
Type 2 diabetes (
29358691
29632382
)
Type 2 diabetes (adjusted for BMI) (
29632382
)
Interacting Genes
48 interacting genes:
AR
BLZF1
CALCOCO2
CCDC170
CCDC33
CCNC
CCT4
CDK2
CDK20
CDK3
CDK6
CDK7
CDK8
CSNK2B
CTBP2
DUSP12
ERCC3
ESR1
FUBP1
GANAB
GOLGA2
GRIPAP1
GTF2E2
GTF2H1
KLC3
MCM7
MCRS1
MTA1
MTMR7
NDC80
NEDD4
PICK1
POLR2A
POLR2B
PPFIA1
PSMA1
RARB
RHOH
SFN
SORBS3
SSX2IP
SUPT5H
TCF4
TP53
TRIM8
TRIML2
ZNF655
ZNRD2
182 interacting genes:
ABLIM1
ADSL
AMMECR1
AP5B1
APEX2
ARHGEF39
ARHGEF5
ARNT2
ATG5
ATOSB
AXIN1
BAHD1
BCL6B
CBX8
CCDC120
CCDC185
CCDC33
CCNH
CDC7
CELA2B
CEP57L1
CHCHD3
CNNM3
CPNE7
CWF19L2
DAXX
DAZAP2
DBNDD2
DCTN4
DCX
DDIT4L
DDX6
DOCK2
DUSP12
DUSP26
EEF1E1
EFHC1
ELOA2
ENKD1
ENTREP1
EXOSC5
FAM107A
FAM161A
FAM168A
FAM90A1
FARS2
FASTK
FBF1
FBXL18
FKBPL
FMR1
FNDC11
FOXD4L3
FUBP3
FXR2
GABARAPL1
GABARAPL2
GATAD2B
GCA
GEMIN4
GIT2
GLYCTK
HDAC4
HDAC7
HLX
HNRNPA1
HNRNPK
HNRNPLL
HOXB5
HOXB9
IL16
IQUB
KANSL1
KAT7
KLHL35
KLHL42
LENG1
LGALS8
LIMS2
LITAF
LMF2
LMO2
LMO4
LNX1
LONRF1
LSM4
MAGOHB
MAP1LC3C
MCM10
METTL17
MID2
MOS
MTPAP
MVP
MXI1
MYH6
MYO6
NAA10
NDN
NFU1
ORC5
PCGF1
PEF1
PEG10
PFDN5
PHF1
PIAS4
POLI
POLR2A
PPP1R18
PRKAA2
PRKAB2
PRPF18
PRPF31
PSMA1
PSME4
PTBP1
PTBP2
RAB35
RABL6
RB1CC1
RBM15
RHPN1
RIN1
RNF11
RPA2
RPL9
RPS27A
RTN4IP1
RTP5
RXRB
SCAND1
SCNM1
SDCBP
SETD5
SHC1
SLC15A3
SMARCD1
SMCP
SNRPB
SPATA24
SRI
STAMBPL1
STK16
TACO1
TBC1D22B
TBRG4
TCL1A
TEKT3
TENT2
TLE5
TNFAIP3
TP53RK
TRAF2
TRAF4
TSC1
TSGA10IP
TTC23L
UBAC2
UBC
ULK1
USP2
VARS1
VPS72
WWP2
ZBTB4
ZC2HC1C
ZNF101
ZNF205
ZNF337
ZNF408
ZNF414
ZNF426
ZNF451
ZNF564
ZNF581
ZNF638
ZNF648
ZNF688
ZNF696
ZNF774
ZNF80
Entrez ID
902
10241
HPRD ID
09059
06846
Ensembl ID
ENSG00000134480
ENSG00000136436
Uniprot IDs
A0A2R8YEM2
P51946
Q13137
PDB IDs
1JKW
1KXU
6O9L
6XBZ
6XD3
7B5O
7B5Q
7EGB
7EGC
7ENA
7ENC
7LBM
7NVR
8BVW
8BYQ
8GXQ
8GXS
8ORM
8P6V
8P6W
8P6X
8P6Y
8P6Z
8P70
8P71
8P72
8P73
8P74
8P75
8P76
8P77
8P78
8P79
8PLZ
8PYR
8S0R
8S0T
2MXP
3VVV
3VVW
4GXL
4HAN
4XKL
5AAQ
5Z7A
5Z7L
7EAA
Enriched GO Terms of Interacting Partners
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Cyclin-dependent Protein Serine/threonine Kinase Activity
Cyclin-dependent Protein Kinase Holoenzyme Complex
DNA-templated Transcription
Transcription By RNA Polymerase II
Nucleoplasm
Nucleus
DNA Damage Response
Cyclin Binding
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Hormone-mediated Signaling Pathway
Regulation Of Nucleobase-containing Compound Metabolic Process
Nucleobase-containing Compound Biosynthetic Process
Regulation Of Mitotic Cell Cycle Phase Transition
Transcription Factor TFIIH Core Complex
Transcription Factor TFIIH Holo Complex
Positive Regulation Of Macromolecule Biosynthetic Process
Transcription Elongation By RNA Polymerase II
Transcription Initiation At RNA Polymerase II Promoter
Protein Binding
Negative Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Primary Metabolic Process
Regulation Of Transcription By RNA Polymerase II
DNA-templated Transcription Elongation
RNA-directed RNA Polymerase Activity
RNA-templated Transcription
Cytoplasm
Regulation Of Cell Cycle
Regulation Of Cell Cycle Phase Transition
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Cell Division
Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Macromolecule Metabolic Process
Regulation Of Macromolecule Metabolic Process
G0 To G1 Transition
TFIIB-class Transcription Factor Binding
Chromatin Binding
Positive Regulation Of Metabolic Process
Viral Process
Negative Regulation Of Stem Cell Proliferation
DNA-templated Transcription Initiation
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Mitotic Cell Cycle
CKM Complex
Regulation Of Metabolic Process
Positive Regulation Of RNA Metabolic Process
DNA Repair
Protein Binding
Nucleus
Regulation Of Nucleobase-containing Compound Metabolic Process
Nucleoplasm
Regulation Of RNA Metabolic Process
Regulation Of Primary Metabolic Process
Regulation Of Macromolecule Metabolic Process
Regulation Of Gene Expression
Regulation Of Metabolic Process
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Macromolecule Biosynthetic Process
Zinc Ion Binding
Cellular Response To Nitrogen Starvation
Ubiquitin Protein Ligase Binding
MRNA Processing
MRNA Metabolic Process
MRNA Binding
Regulation Of RNA Splicing
Cytoplasm
RNA Splicing
Negative Regulation Of Macromolecule Biosynthetic Process
Nucleic Acid Metabolic Process
RNA Metabolic Process
Metal Ion Binding
Regulation Of Transcription By RNA Polymerase II
DNA Binding
Chromatin Organization
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Biosynthetic Process
Cellular Response To Nutrient Levels
RNA Processing
Macromolecule Metabolic Process
Response To Starvation
Autophagy Of Mitochondrion
Spliceosomal Complex
Epigenetic Regulation Of Gene Expression
Negative Regulation Of RNA Metabolic Process
Nuclear Speck
Regulation Of MRNA Metabolic Process
Autophagosome
Autophagosome Membrane
Negative Regulation Of Metabolic Process
Regulation Of Translation At Presynapse, Modulating Synaptic Transmission
SnRNP Binding
Mitophagy
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Phosphatidylethanolamine Binding
Negative Regulation Of Gene Expression
Cytoplasmic Stress Granule
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Tagcloud (Intersection)
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