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WASL and ARPC3
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
56
Data Source:
BioGRID
(two hybrid, two hybrid)
WASL
ARPC3
Description
WASP like actin nucleation promoting factor
actin related protein 2/3 complex subunit 3
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Endoplasmic Reticulum Membrane
Cytosol
Cytoskeleton
Plasma Membrane
Actin Cytoskeleton
Lamellipodium
Actin Cap
Endocytic Vesicle Membrane
Cytoplasmic Vesicle
Extracellular Exosome
Glutamatergic Synapse
Nucleus
Cytoplasm
Cytosol
Cytoskeleton
Arp2/3 Protein Complex
Focal Adhesion
Actin Cytoskeleton
Membrane
Lamellipodium
Cell Leading Edge
Filamentous Actin
Site Of Double-strand Break
Cell Projection
Growth Cone Leading Edge
Extracellular Exosome
Molecular Function
Actin Binding
Protein Binding
GTPase Regulator Activity
Actin Binding
Structural Constituent Of Cytoskeleton
Protein Binding
Actin Filament Binding
Biological Process
Vesicle Budding From Membrane
Actin Filament Organization
Actin Polymerization Or Depolymerization
Response To Bacterium
Vesicle Organization
Actin Cytoskeleton Organization
Actin Filament Polymerization
Vesicle Transport Along Actin Filament
Protein-containing Complex Localization
Regulation Of Protein Localization
Positive Regulation Of Transcription By RNA Polymerase II
Cell Division
Positive Regulation Of Filopodium Assembly
Spindle Localization
Dendritic Spine Morphogenesis
Protein-containing Complex Assembly
Regulation Of Postsynapse Organization
Negative Regulation Of Membrane Tubulation
Positive Regulation Of Clathrin-dependent Endocytosis
Negative Regulation Of Lymphocyte Migration
Regulation Of Actin Filament Polymerization
Arp2/3 Complex-mediated Actin Nucleation
Actin Polymerization-dependent Cell Motility
Regulation Of Synaptic Vesicle Endocytosis
Cellular Response To Nerve Growth Factor Stimulus
Pathways
Regulation of actin dynamics for phagocytic cup formation
Regulation of actin dynamics for phagocytic cup formation
NOSTRIN mediated eNOS trafficking
Nephrin family interactions
EPHB-mediated forward signaling
EPHB-mediated forward signaling
DCC mediated attractive signaling
RHO GTPases Activate WASPs and WAVEs
RHO GTPases Activate WASPs and WAVEs
Clathrin-mediated endocytosis
CDC42 GTPase cycle
RAC1 GTPase cycle
RHOQ GTPase cycle
RHOJ GTPase cycle
RHOV GTPase cycle
FCGR3A-mediated phagocytosis
FCGR3A-mediated phagocytosis
Regulation of actin dynamics for phagocytic cup formation
Regulation of actin dynamics for phagocytic cup formation
EPHB-mediated forward signaling
RHO GTPases Activate WASPs and WAVEs
RHO GTPases Activate WASPs and WAVEs
Clathrin-mediated endocytosis
FCGR3A-mediated phagocytosis
FCGR3A-mediated phagocytosis
Drugs
N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide
(2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one
Diseases
GWAS
High light scatter reticulocyte count (
32888494
)
High light scatter reticulocyte percentage of red cells (
32888494
)
Platelet count (
22139419
27863252
)
Plateletcrit (
27863252
)
Reticulocyte count (
32888494
)
Reticulocyte fraction of red cells (
32888494
)
Automobile speeding propensity (
30643258
)
Bipolar disorder (
31043756
)
Femoral neck bone mineral density (
30172743
)
Interacting Genes
62 interacting genes:
ABI2
ABL1
ACTG1
ACTR2
ACTR3
APBB1
APP
ARPC3
ARPC4
BIN1
CDC42
CORO7
CTTN
DNMBP
EGFR
EVL
FCHSD2
FNBP1
FNBP1L
GRB2
HP
HSP90AA1
HSP90AB1
IPO5
ITCH
ITGB1BP2
ITSN1
ITSN2
LCK
NCK1
NCK2
NCKIPSD
OSTF1
PACSIN1
PACSIN2
PACSIN3
PFN1
PRMT2
PRPF40A
PSTPIP1
PTK6
RHOQ
RIPPLY3
RNF8
RPL7AP66
SDCBP
SH3GL3
SH3RF1
SNX9
SORBS2
SRC
TNNT3
TRIP10
UBASH3A
UBASH3B
VASP
VIPR1
WIPF1
WIPF2
WIPF3
WWP1
ZNF395
31 interacting genes:
ACTR3
ARAP1
ARPC4
BAG6
CCR10
CDKN2B
CEBPA
CETP
DUSP29
EFTUD2
FAM9A
GOLGA2
HOXA3
LATS1
LGALS4
LTA4H
MAPK6
NRIP1
OTUD5
POU2F1
PRMT1
RBBP8NL
RETREG3
RPS4X
SYBU
TARS3
THNSL2
WAS
WASF2
WASL
ZNF576
Entrez ID
8976
10094
HPRD ID
05448
09175
Ensembl ID
ENSG00000106299
ENSG00000111229
Uniprot IDs
O00401
O15145
PDB IDs
2FF3
2LNH
2VCP
4CC2
4CC7
9DLX
6UHC
6YW6
6YW7
8P94
Enriched GO Terms of Interacting Partners
?
Endocytosis
Actin Filament Organization
Positive Regulation Of Cellular Component Biogenesis
Positive Regulation Of Supramolecular Fiber Organization
Positive Regulation Of Actin Filament Polymerization
Import Into Cell
Positive Regulation Of Cellular Component Organization
Supramolecular Fiber Organization
Cytoplasm
Cytosol
Positive Regulation Of Protein Polymerization
Regulation Of Actin Filament Organization
Regulation Of Actin Cytoskeleton Organization
Positive Regulation Of Cytoskeleton Organization
Regulation Of Cellular Component Organization
Profilin Binding
Regulation Of Actin Filament-based Process
Regulation Of Supramolecular Fiber Organization
Regulation Of Actin Filament Polymerization
Actin Filament-based Process
Positive Regulation Of Cell Projection Organization
Regulation Of Actin Polymerization Or Depolymerization
Regulation Of Actin Filament Length
Regulation Of Endocytosis
Positive Regulation Of Protein-containing Complex Assembly
Vesicle-mediated Transport
Regulation Of Cell Projection Organization
Cytoskeleton Organization
Regulation Of Protein-containing Complex Assembly
Positive Regulation Of Organelle Organization
Actin Cytoskeleton Organization
Regulation Of Cytoskeleton Organization
Lamellipodium
Regulation Of Cellular Component Size
Cytoskeletal Anchor Activity
Regulation Of Plasma Membrane Bounded Cell Projection Organization
Cell Projection
Focal Adhesion
Regulation Of Cell Projection Assembly
Cytoskeleton
Plasma Membrane Tubulation
Actin Polymerization Or Depolymerization
Positive Regulation Of Lamellipodium Organization
Proline-rich Region Binding
Arp2/3 Complex-mediated Actin Nucleation
Extracellular Exosome
SH3 Domain Binding
Regulation Of Vesicle-mediated Transport
Actin Binding
Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly
Regulation Of Cell Projection Assembly
Negative Regulation Of Actin Filament Bundle Assembly
Actin Filament Polymerization
Regulation Of Lamellipodium Assembly
Negative Regulation Of Stress Fiber Assembly
Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly
Regulation Of Actin Filament Organization
Actin Filament Organization
Regulation Of Lamellipodium Organization
Arp2/3 Protein Complex
Actin Polymerization Or Depolymerization
Actin Cytoskeleton
Actin Filament-based Movement
HMG Box Domain Binding
Asymmetric Cell Division
Protein Polymerization
Regulation Of Actin Cytoskeleton Organization
Nucleus
Arp2/3 Complex-mediated Actin Nucleation
Positive Regulation Of Cell Projection Organization
Actin Binding
Regulation Of Actin Filament-based Process
Regulation Of Stress Fiber Assembly
Regulation Of Supramolecular Fiber Organization
Site Of Double-strand Break
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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