WASL and FNBP1

Number of citations of the paper that reports this interaction (PMID 14732713)
5

Data Source:
HPRD (in vivo, in vitro)

		WASL	FNBP1
Gene Name		Wiskott-Aldrich syndrome-like	formin binding protein 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane Actin Cytoskeleton Cytoplasmic Membrane-bounded Vesicle Lamellipodium Actin Cap Endocytic Vesicle Membrane Extracellular Vesicular Exosome	Lysosome Cytoskeleton Plasma Membrane Coated Pit Cell Cortex Cytoplasmic Membrane-bounded Vesicle
	Molecular Function	Actin Binding Small GTPase Regulator Activity Protein Binding	Protein Binding Lipid Binding Identical Protein Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Protein Complex Assembly Membrane Budding Movement Of Cell Or Subcellular Component Mitotic Nuclear Division Axon Guidance Actin Polymerization Or Depolymerization Response To Bacterium Vesicle Organization Vesicle Transport Along Actin Filament Regulation Of Protein Localization Cellular Protein Complex Localization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Small Molecule Metabolic Process Innate Immune Response Nitric Oxide Metabolic Process Ephrin Receptor Signaling Pathway Regulation Of Nitric-oxide Synthase Activity Cell Division Positive Regulation Of Filopodium Assembly Spindle Localization Negative Regulation Of Membrane Tubulation Positive Regulation Of Clathrin-mediated Endocytosis Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation	Endocytosis
Pathways		Axon guidance DCC mediated attractive signaling EPHB-mediated forward signaling Metabolism of nitric oxide NOSTRIN mediated eNOS trafficking EPH-Ephrin signaling Nephrin interactions eNOS activation and regulation Netrin-1 signaling Fcgamma receptor (FCGR) dependent phagocytosis Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS		Platelet counts ( 22139419)
Protein-Protein Interactions		47 interactors: ABL1 ACTG1 ACTR2 ACTR3 APBB1 APP ARPC3 BAIAP2 CDC42 CTTN DNMBP EVL FCHSD2 FNBP1 FNBP1L GRB2 HP HSP90AA1 HSP90AB1 IPO5 ITSN1 ITSN2 LCK NCK1 NCK2 NCKIPSD PACSIN1 PACSIN2 PACSIN3 PFN1 PRPF40A PSTPIP1 PTK6 RHOJ RHOQ RNF8 RPL7AP66 SDCBP SH3GL3 SNX9 SRC TRIP10 VASP VIPR1 WIPF1 WIPF2 ZNF395	13 interactors: AKAP9 ARHGAP17 CBL CDC42 DNM1 DNM2 FASLG ITSN1 PDE6G RND2 SNX2 TNKS WASL
Entrez ID		8976	23048
HPRD ID		05448	10446
Ensembl ID		ENSG00000106299	ENSG00000187239
Uniprot IDs		O00401	B7ZL12 B7ZL13 B7ZL14 Q96RU3
PDB IDs		2FF3 2LNH 2VCP	2EFL
Enriched GO Terms of Interacting Partners?		Endocytosis Vesicle-mediated Transport Actin Filament-based Process Actin Cytoskeleton Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Cytoskeleton Organization Cell Projection Morphogenesis Immune Response-activating Cell Surface Receptor Signaling Pathway Cell Part Morphogenesis Neuron Projection Morphogenesis Axon Guidance Fc Receptor Signaling Pathway Axonogenesis Immune Response-regulating Cell Surface Receptor Signaling Pathway Cell Morphogenesis Positive Regulation Of Cellular Component Biogenesis Axon Development Neuron Projection Development Cell Morphogenesis Involved In Neuron Differentiation Cell Projection Organization Phagocytosis Immune Response-regulating Signaling Pathway Neuron Development Movement Of Cell Or Subcellular Component Cell Morphogenesis Involved In Differentiation Chemotaxis Locomotion Actin Filament Organization Innate Immune Response Neuron Differentiation Organelle Organization Positive Regulation Of Protein Complex Assembly Regulation Of Cellular Component Organization Positive Regulation Of Immune Response Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Immune Response Positive Regulation Of Actin Filament Polymerization Generation Of Neurons Positive Regulation Of Protein Polymerization Positive Regulation Of Immune System Process Regulation Of Protein Complex Assembly Neurogenesis Regulation Of Actin Cytoskeleton Organization Immune System Process Anatomical Structure Morphogenesis Transport Defense Response Regulation Of Immune Response	Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Signal Transduction Ephrin Receptor Signaling Pathway Negative Regulation Of Membrane Tubulation Signaling Cell Communication Endocytosis Cellular Response To Stimulus Cell Projection Morphogenesis Cell Part Morphogenesis Cell Morphogenesis Neuron Projection Morphogenesis Cell Projection Organization Cell Development Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Establishment Of Organelle Localization Response To Stimulus Positive Regulation Of Signal Transduction Axon Guidance Positive Regulation Of Intracellular Signal Transduction Neuron Projection Development Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Vesicle-mediated Transport Organelle Localization Cell Surface Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of ERBB Signaling Pathway Cell-cell Signaling Generation Of Neurons Regulation Of Catalytic Activity Neuron Development Regulation Of Cell Projection Organization Nitric Oxide Metabolic Process Anatomical Structure Morphogenesis Cell Differentiation Positive Regulation Of Metabolic Process Neurogenesis Reactive Nitrogen Species Metabolic Process Endosome Organization Axonogenesis Positive Regulation Of Cellular Metabolic Process Establishment Of Vesicle Localization Regulation Of Intracellular Signal Transduction Vesicle Localization Positive Regulation Of Receptor-mediated Endocytosis Axon Development Regulation Of Nitric-oxide Synthase Activity Anatomical Structure Development Response To External Stimulus
Tagcloud ?		148a biomarker biopsies cg consensus consequences downregulated dysregulated ectopic emsa hypermethylation integrin methylated micrornas mir mirna mirnas nasopharyngeal np npc oncogenes pivotal rock1 stimulatory supporting suppressing unmethylated usf1 vav2	11p 12p 17q11 6q16 9p21 9q34 af10 c9orf78 calm concurring cryptic del grik2 hoxa imbalances immunophenotyping interphase inup214 leukemias lymphoblastic nup214 q11 q12 q34 q35 taf tcrb tlx3 usp20
Tagcloud (Difference) ?		148a biomarker biopsies cg consensus consequences downregulated dysregulated ectopic emsa hypermethylation integrin methylated micrornas mir mirna mirnas nasopharyngeal np npc oncogenes pivotal rock1 stimulatory supporting suppressing unmethylated usf1 vav2	11p 12p 17q11 6q16 9p21 9q34 af10 c9orf78 calm concurring cryptic del grik2 hoxa imbalances immunophenotyping interphase inup214 leukemias lymphoblastic nup214 q11 q12 q34 q35 taf tcrb tlx3 usp20
Tagcloud (Intersection) ?