WASL and DNMBP

Number of citations of the paper that reports this interaction (PubMedID 14506234)
0

Data Source:
HPRD (in vitro)

		WASL	DNMBP
Description		WASP like actin nucleation promoting factor	dynamin binding protein
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Cytosol Cytoskeleton Plasma Membrane Actin Cytoskeleton Lamellipodium Actin Cap Endocytic Vesicle Membrane Cytoplasmic Vesicle Extracellular Exosome Glutamatergic Synapse	Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Golgi Stack Cytosol Cytoskeleton Cell-cell Junction Nuclear Body Synapse Anchoring Junction Presynapse
	Molecular Function	Actin Binding Protein Binding GTPase Regulator Activity	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Vesicle Budding From Membrane Actin Filament Organization Actin Polymerization Or Depolymerization Response To Bacterium Vesicle Organization Actin Cytoskeleton Organization Actin Filament Polymerization Vesicle Transport Along Actin Filament Protein-containing Complex Localization Regulation Of Protein Localization Positive Regulation Of Transcription By RNA Polymerase II Cell Division Positive Regulation Of Filopodium Assembly Spindle Localization Dendritic Spine Morphogenesis Protein-containing Complex Assembly Regulation Of Postsynapse Organization Negative Regulation Of Membrane Tubulation Positive Regulation Of Clathrin-dependent Endocytosis Negative Regulation Of Lymphocyte Migration	Regulation Of Cell Shape Intracellular Signal Transduction Regulation Of Small GTPase Mediated Signal Transduction Cilium Assembly
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation NOSTRIN mediated eNOS trafficking Nephrin family interactions EPHB-mediated forward signaling EPHB-mediated forward signaling DCC mediated attractive signaling RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs Clathrin-mediated endocytosis CDC42 GTPase cycle RAC1 GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle RHOV GTPase cycle FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis	CDC42 GTPase cycle
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Platelet count ( 22139419 27863252) Plateletcrit ( 27863252) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Stent thrombosis in response to clopidogrel treatment ( 32472697)
Interacting Genes		62 interacting genes: ABI2 ABL1 ACTG1 ACTR2 ACTR3 APBB1 APP ARPC3 ARPC4 BIN1 CDC42 CORO7 CTTN DNMBP EGFR EVL FCHSD2 FNBP1 FNBP1L GRB2 HP HSP90AA1 HSP90AB1 IPO5 ITCH ITGB1BP2 ITSN1 ITSN2 LCK NCK1 NCK2 NCKIPSD OSTF1 PACSIN1 PACSIN2 PACSIN3 PFN1 PRMT2 PRPF40A PSTPIP1 PTK6 RHOQ RIPPLY3 RNF8 RPL7AP66 SDCBP SH3GL3 SH3RF1 SNX9 SORBS2 SRC TNNT3 TRIP10 UBASH3A UBASH3B VASP VIPR1 WIPF1 WIPF2 WIPF3 WWP1 ZNF395	21 interacting genes: ACTA1 ARHGAP17 BUB1B CDC42 CNN1 CYFIP2 DBN1 DNM1 ENAH EVL FASLG HSPA1B KHDRBS1 NCKAP1 RAC1 RAPH1 UBC VASP WASF1 WASL WIPF2
Entrez ID		8976	23268
HPRD ID		05448	10918
Ensembl ID		ENSG00000106299	ENSG00000107554
Uniprot IDs		O00401	A0A1B0GTX1 A0A1C7CYY6 B3KY33 Q6XZF7
PDB IDs		2FF3 2LNH 2VCP 4CC2 4CC7 9DLX	1UG1 1UHC 4CC2 4CC3 4CC4 4CC7 4GLM
Enriched GO Terms of Interacting Partners?		Endocytosis Actin Filament Organization Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Actin Filament Polymerization Import Into Cell Positive Regulation Of Cellular Component Organization Supramolecular Fiber Organization Cytoplasm Cytosol Positive Regulation Of Protein Polymerization Regulation Of Actin Filament Organization Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Cytoskeleton Organization Regulation Of Cellular Component Organization Profilin Binding Regulation Of Actin Filament-based Process Regulation Of Supramolecular Fiber Organization Regulation Of Actin Filament Polymerization Actin Filament-based Process Positive Regulation Of Cell Projection Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Regulation Of Endocytosis Positive Regulation Of Protein-containing Complex Assembly Vesicle-mediated Transport Regulation Of Cell Projection Organization Cytoskeleton Organization Regulation Of Protein-containing Complex Assembly Positive Regulation Of Organelle Organization Actin Cytoskeleton Organization Regulation Of Cytoskeleton Organization Lamellipodium Regulation Of Cellular Component Size Cytoskeletal Anchor Activity Regulation Of Plasma Membrane Bounded Cell Projection Organization Cell Projection Focal Adhesion Regulation Of Cell Projection Assembly Cytoskeleton Plasma Membrane Tubulation Actin Polymerization Or Depolymerization Positive Regulation Of Lamellipodium Organization Proline-rich Region Binding Arp2/3 Complex-mediated Actin Nucleation Extracellular Exosome SH3 Domain Binding Regulation Of Vesicle-mediated Transport Actin Binding Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly	Actin Filament Organization Lamellipodium Cytoskeleton Actin Polymerization Or Depolymerization Supramolecular Fiber Organization Profilin Binding Focal Adhesion Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Regulation Of Cytoskeleton Organization Actin Binding Regulation Of Actin Filament-based Process Regulation Of Supramolecular Fiber Organization Regulation Of Actin Filament Organization Filopodium Neuron Projection Development Positive Regulation Of Protein Polymerization Actin Cytoskeleton Organization SH3 Domain Binding Positive Regulation Of Cellular Component Organization Postsynapse SCAR Complex Positive Regulation Of Actin Filament Polymerization Regulation Of Actin Filament Polymerization Actin Filament-based Process Plasma Membrane Bounded Cell Projection Organization Regulation Of Organelle Organization Regulation Of Cellular Component Size Regulation Of Protein-containing Complex Assembly Regulation Of Postsynapse Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Cellular Component Organization Regulation Of Actin Filament Length Actin Cytoskeleton Positive Regulation Of Organelle Organization Positive Regulation Of Cellular Component Biogenesis Cell Projection Organization Cytoplasm Rac Protein Signal Transduction Positive Regulation Of Protein-containing Complex Assembly Cytosol Positive Regulation Of Lamellipodium Assembly Axon Guidance Neuron Projection Guidance Cell Projection Regulation Of Cell Projection Assembly Actin Filament Polymerization Extracellular Exosome Positive Regulation Of Lamellipodium Organization
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?