CTGF

Gene Name		connective tissue growth factor
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Proteinaceous Extracellular Matrix Extracellular Space Golgi Apparatus Cis-Golgi Network Cytosol Plasma Membrane Cell Cortex Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm
	Molecular Function	Fibronectin Binding Integrin Binding Protein Binding Insulin-like Growth Factor Binding Growth Factor Activity Heparin Binding
	Biological Process	Cartilage Condensation Ossification Angiogenesis Regulation Of Cell Growth Tissue Homeostasis Positive Regulation Of Protein Phosphorylation Transcription Initiation From RNA Polymerase II Promoter Cell Adhesion Cell-matrix Adhesion Integrin-mediated Signaling Pathway Cell-cell Signaling Positive Regulation Of Cell Proliferation Fibroblast Growth Factor Receptor Signaling Pathway Epidermis Development Response To Wounding Response To Glucose Organ Senescence Gene Expression Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Cell Migration Cell Differentiation Lung Development Regulation Of Chondrocyte Differentiation Response To Estradiol Positive Regulation Of Collagen Biosynthetic Process Response To Anoxia Intracellular Signal Transduction Chondrocyte Proliferation Response To Amino Acid Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Response To Peptide Hormone Cellular Lipid Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Cell Differentiation Positive Regulation Of JNK Cascade Positive Regulation Of Cell Activation Response To Mineralocorticoid Positive Regulation Of Stress Fiber Assembly Cytosolic Calcium Ion Transport Positive Regulation Of Cardiac Muscle Contraction Negative Regulation Of Cell Death Extracellular Matrix Constituent Secretion Positive Regulation Of G0 To G1 Transition Positive Regulation Of ERK1 And ERK2 Cascade Response To Fatty Acid DNA Biosynthetic Process Reactive Oxygen Species Metabolic Process
Pathways		PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Generic Transcription Pathway Metabolism of lipids and lipoproteins YAP1- and WWTR1 (TAZ)-stimulated gene expression Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-protein Interactions		11 interactors: ACTB AP3D1 ERBB4 FBLN1 HSPG2 LRP1 NOV TGFB1 TGFB2 TGFB3 VEGFA
Entrez ID		1490
HPRD ID		00412
Ensembl ID		ENSG00000118523
Uniprot IDs		P29279 Q5M8T4
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Macrophage Cytokine Production Salivary Gland Morphogenesis SMAD Protein Import Into Nucleus Salivary Gland Development Exocrine System Development Platelet Activation Platelet Degranulation Gland Development Anatomical Structure Morphogenesis Regulation Of Body Fluid Levels Regulation Of Cell Migration Wound Healing Developmental Process Regulation Of Cell Motility Response To External Stimulus Uterine Wall Breakdown Positive Regulation Of Cell Division Regulation Of Locomotion Positive Regulation Of Protein Transport Regulation Of Cellular Component Movement Response To Wounding Positive Regulation Of Transport Extracellular Matrix Organization Extracellular Structure Organization Regulation Of Immune System Process Positive Regulation Of Epithelial To Mesenchymal Transition Regulation Of Protein Localization Face Morphogenesis Head Development Gland Morphogenesis Positive Regulation Of Cell Morphogenesis Involved In Differentiation Blood Coagulation Hemostasis Mammary Gland Development Vesicle-mediated Transport Head Morphogenesis Positive Regulation Of MAPK Cascade Multicellular Organismal Development Movement Of Cell Or Subcellular Component Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Ossification Involved In Bone Remodeling Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Cell Death Positive Regulation Of Kinase Activity Growth Response To Progesterone Face Development Frontal Suture Morphogenesis Positive Regulation Of Stem Cell Differentiation Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Tagcloud ?		additively away bsc connective diphosphate edge egr encode fibronectin fn gro hour hsp int message monolayer nak nonwounded osteopontin pa pai plasminogen potentiate quiescent scrape stimulator urokinase wound wounding