PKMYT1 and ABHD16A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PKMYT1	ABHD16A
Description		protein kinase, membrane associated tyrosine/threonine 1	abhydrolase domain containing 16A, phospholipase
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Nucleoplasm Nucleolus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Membrane	Membrane
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Metal Ion Binding Protein Serine Kinase Activity	Phospholipase Activity Phosphatidylcholine Lysophospholipase Activity Protein Binding Hydrolase Activity Monoacylglycerol Lipase Activity
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Regulation Of Mitotic Nuclear Division Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Meiotic Cell Cycle Negative Regulation Of G2/MI Transition Of Meiotic Cell Cycle	Lipid Metabolic Process Phosphatidylserine Catabolic Process Monoacylglycerol Catabolic Process Prostaglandin Catabolic Process
Pathways		Polo-like kinase mediated events Cyclin A/B1/B2 associated events during G2/M transition G2/M DNA replication checkpoint
Drugs		Fostamatinib
Diseases
GWAS		Metabolic syndrome ( 20694148)	Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Monocyte percentage of white cells ( 32888494) Ulcerative colitis ( 28067908)
Interacting Genes		24 interacting genes: ABHD16A BCL2 CCNB1 CD3E CD79A CDK1 CLDN8 ELOVL4 FATE1 LIME1 LRRC25 MAPK10 MAPK8 PIN1 PLK1 RETREG3 SLC10A1 SLC30A8 SLC61A1 SLC71A2 STEAP3 TMEM101 TMEM229B TMX2	69 interacting genes: AGPAT3 AQP6 AQP7 ATP5MC3 ATP5PF BRI3 CBARP CIDEB CREB3 CYP1A2 DNAJC1 DTX2 EBP ERGIC3 FDPS FKBP7 GDAP1 GJA5 GOLT1A GORAB GPR152 GPRC5C GYPC HM13 HNRNPA1 HSD17B13 IFITM1 IFITM3 ITGAM LTA MLH1 MT-ND3 MT-ND4 PERP PILRB PKMYT1 POLE PRAF2 PTGS2 RETREG3 RHBDD2 RHBDL1 RNF5 SAFB SEC22B SERF1A SERF1B SLC10A1 SLC30A2 SLC7A8 SPAG4 SPAG7 STMN4 STX1B TM4SF19 TMEM139 TMEM143 TMEM147 TMEM14B TMEM222 TMEM237 TMEM31 TMEM65 TSPAN2 UNC93A UPF1 VAMP5 VMA21 WBP1L
Entrez ID		9088	7920
HPRD ID		03920	15929
Ensembl ID		ENSG00000127564	ENSG00000204427
Uniprot IDs		Q0IJ49 Q99640	A0A1U9X777 B3KNX9 O95870
PDB IDs		3P1A 5VCV 5VCW 5VCX 5VCY 5VCZ 5VD0 5VD1 5VD3 8D6C 8D6D 8D6E 8D6F 8WJY 8ZTX 8ZU2 8ZUD 8ZUL
Enriched GO Terms of Interacting Partners?		Membrane Immune Response-regulating Cell Surface Receptor Signaling Pathway Cyclin B1-CDK1 Complex Protein Localization To Site Of Double-strand Break JUN Kinase Activity Positive Regulation Of Mitochondrial ATP Synthesis Coupled Electron Transport B Cell Receptor Complex Immune Response-regulating Signaling Pathway Mitotic Cell Cycle Phase Transition Antigen Receptor-mediated Signaling Pathway B Cell Receptor Signaling Pathway G2/M Transition Of Mitotic Cell Cycle Cell Cycle Phase Transition Cell Cycle G2/M Phase Transition Ventricular Cardiac Muscle Cell Development Mitotic Nuclear Membrane Disassembly Striated Muscle Cell Development Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Membrane Disassembly Nuclear Membrane Disassembly MAP Kinase Activity Muscle Cell Development Immune Response-activating Cell Surface Receptor Signaling Pathway Response To Toxic Substance Regulation Of Sister Chromatid Segregation Regulation Of Attachment Of Spindle Microtubules To Kinetochore Outer Kinetochore Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Localization To Chromosome Peptidyl-threonine Phosphorylation Microtubule Polymerization Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site Regulation Of Circadian Rhythm Fc-epsilon Receptor Signaling Pathway Lymphocyte Proliferation Regulation Of Mitotic Cell Cycle Regulation Of Mitotic Nuclear Division Regulation Of Cell Cycle G2/M Phase Transition Mononuclear Cell Proliferation Positive Regulation Of Cardiac Muscle Cell Proliferation Endoplasmic Reticulum Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Microtubule Cytoskeleton Organization Involved In Mitosis Positive Regulation Of Chromosome Segregation Regulation Of Chromosome Segregation Cellular Response To Hypoxia Response To Iron Ion Positive Regulation Of Cell Cycle G2/M Phase Transition Response To Light Stimulus	Membrane Endoplasmic Reticulum Membrane Protein Binding Endoplasmic Reticulum
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