SYNGAP1 and DLGAP4

Number of citations of the paper that reports this interaction (PMID 9581761)
71

Data Source:
HPRD (two hybrid, in vivo)

		SYNGAP1	DLGAP4
Gene Name		synaptic Ras GTPase activating protein 1	discs, large (Drosophila) homolog-associated protein 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Intrinsic Component Of The Cytoplasmic Side Of The Plasma Membrane Dendritic Shaft	Membrane Synapse
	Molecular Function	Rab GTPase Activator Activity Ras GTPase Activator Activity SH3 Domain Binding	Protein Binding
	Biological Process	Ras Protein Signal Transduction Pattern Specification Process Visual Learning Dendrite Development Positive Regulation Of Ras GTPase Activity Positive Regulation Of Rab GTPase Activity Receptor Clustering Regulation Of MAPK Cascade Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Ras Protein Signal Transduction Regulation Of Synaptic Plasticity Regulation Of Long-term Neuronal Synaptic Plasticity Negative Regulation Of Axonogenesis Regulation Of Synapse Structure Or Activity	Cell-cell Signaling
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: CAMK2A DLG3 DLG4 DLGAP4 GRIN1 GRIN2B GRIN2D KDR MPDZ PDGFRB TRIP6 ULK1 ULK2	15 interactors: BIN1 DLG1 DLG3 DLG4 EXOC4 GRIN1 GRIN2D PLP2 PPP1R1B SH3GL2 SHANK2 SHANK3 SORBS2 SYNGAP1 UBC
Entrez ID		8831	22839
HPRD ID		16018	16826
Ensembl ID		ENSG00000197283	ENSG00000080845
Uniprot IDs		Q96PV0	Q9Y2H0
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Autophosphorylation Cell-cell Signaling Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Synaptic Transmission Signaling Startle Response Cell Communication Neuron Projection Morphogenesis Neuromuscular Process Cell Development Cell Morphogenesis Involved In Differentiation Response To External Stimulus Locomotion Regulation Of Synaptic Plasticity Synaptic Transmission, Glutamatergic Ionotropic Glutamate Receptor Signaling Pathway Neuron Projection Development Cell Projection Morphogenesis Signal Transduction Cell Part Morphogenesis Regulation Of Neuronal Synaptic Plasticity Movement Of Cell Or Subcellular Component Glutamate Receptor Signaling Pathway Negative Regulation Of Collateral Sprouting Neuron Development Neuron-neuron Synaptic Transmission Receptor Localization To Synapse Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Potential Anatomical Structure Morphogenesis Cell Morphogenesis Chemotaxis Neuron Differentiation Cell Projection Organization Regulation Of Synaptic Transmission Phosphorylation Membrane Depolarization Cellular Response To Stimulus Protein Localization To Synapse Axon Guidance Learning System Development Regulation Of Signaling Suckling Behavior Nervous System Development Regulation Of Axonogenesis Single-organism Behavior Generation Of Neurons	Receptor Clustering Learning Regulation Of Long-term Neuronal Synaptic Plasticity Single-organism Behavior Social Behavior Learning Or Memory Receptor Localization To Synapse Membrane Organization Cognition Synaptic Transmission Behavior Regulation Of Neuronal Synaptic Plasticity Regulation Of Synaptic Plasticity Vocalization Behavior Protein Localization To Synapse Neuron Projection Development Cell-cell Signaling Establishment Or Maintenance Of Apical/basal Cell Polarity Neuron Development Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Synaptic Transmission Positive Regulation Of Excitatory Postsynaptic Membrane Potential Chemotaxis Generation Of Neurons Neuron Projection Morphogenesis Nervous System Development Protein Localization To Membrane Positive Regulation Of Membrane Potential Neurogenesis Neuron Differentiation Cell Projection Organization Neurological System Process Cell Morphogenesis Involved In Differentiation Axon Guidance Adult Behavior Response To External Stimulus Locomotion Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering Nucleotide Phosphorylation Cell Projection Morphogenesis Visual Learning Cell Part Morphogenesis Visual Behavior Regulation Of Excitatory Postsynaptic Membrane Potential Axonogenesis Regulation Of Postsynaptic Membrane Potential Synapse Assembly Axon Development Associative Learning Regulation Of Membrane Potential
Tagcloud ?		asah1 atypical broadening canada care4rare causal definitive descriptions encephalopathy epilepsy exome families folr1 forge grin2a kcnq2 nation projects rare recognizable retrospect scn8a segregating seizures suited synj1 translating unrevealing wes
Tagcloud (Difference) ?		asah1 atypical broadening canada care4rare causal definitive descriptions encephalopathy epilepsy exome families folr1 forge grin2a kcnq2 nation projects rare recognizable retrospect scn8a segregating seizures suited synj1 translating unrevealing wes
Tagcloud (Intersection) ?