RIPK1 and MAP3K8

  • Number of citations of the paper that reports this interaction (PMID 16291755)
  • 3
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo)

RIPK1

MAP3K8

Gene Name receptor (TNFRSF)-interacting serine-threonine kinase 1 mitogen-activated protein kinase kinase kinase 8
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions 45 interactors: BIRC2 BIRC3 CASP8 CCDC50 CDC42BPB CFLAR CRADD EGFR FADD FAS HSP90AA1 IKBKB IKBKG ITCH MAP3K14 MAP3K3 MAP3K8 NFKB1 NUMBL OTUD1 PELI1 PTK2 RIPK3 RNF11 RNF216 SQSTM1 TAX1BP1 TICAM1 TNF TNFAIP3 TNFRSF10A TNFRSF10B TNFRSF1A TRADD TRAF1 TRAF2 TRAF3 TRAF5 TRIM38 TRPC4AP UBE2N USP2 XIAP YOD1 ZFAND5 17 interactors: ACY3 AKT1 BMPR2 CD40 CHUK MAP2K1 MAP2K4 MAP3K14 NFKB1 NFKB2 REL RELA RIPK1 STIP1 TNIP2 TRAF2 TRAF6
Entrez ID 8737 1326
HPRD ID 04583 01863
Ensembl ID ENSG00000137275 ENSG00000107968
Uniprot IDs Q13546 P41279
PDB IDs 4ITH 4ITI 4ITJ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
allowed  autocrine  back  deficient  endoplasmic  er  instead  interacting  intrinsic  kills  l929  lineage  lymphotoxin  mlkl  necroptosis  necrosis  opportunities  pathologies  protect  remarkably  repression  rescue  reticulum  ripk3  stress  stressors  switch  tnfr1  unresolved 
10r2  22r1  chorioallantoic  cl41  controlling  correlate  erk  helper  il  influences  jb6  jnk  jun  knockdown  mcf7  mediators  mef  mek  mek1  microenvironment  modulate  pin1  promoting  reactions  secreted  stat3  th17  tumorigenesis  tumorigenicity 
Tagcloud (Difference) ?
allowed  autocrine  back  deficient  endoplasmic  er  instead  interacting  intrinsic  kills  l929  lineage  lymphotoxin  mlkl  necroptosis  necrosis  opportunities  pathologies  protect  remarkably  repression  rescue  reticulum  ripk3  stress  stressors  switch  tnfr1  unresolved 
10r2  22r1  chorioallantoic  cl41  controlling  correlate  erk  helper  il  influences  jb6  jnk  jun  knockdown  mcf7  mediators  mef  mek  mek1  microenvironment  modulate  pin1  promoting  reactions  secreted  stat3  th17  tumorigenesis  tumorigenicity 
Tagcloud (Intersection) ?