HMP19 and RPS27

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		HMP19	RPS27
Gene Name		HMP19 protein	ribosomal protein S27
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane Cytoplasmic Vesicle Membrane Golgi Cisterna Membrane Multivesicular Body Membrane	Nucleus Cytosol Ribosome Cytosolic Small Ribosomal Subunit
	Molecular Function	Clathrin Light Chain Binding	DNA Binding Structural Constituent Of Ribosome Protein Binding Zinc Ion Binding Poly(A) RNA Binding
	Biological Process	Dopamine Receptor Signaling Pathway Clathrin Coat Assembly	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Mitotic Cell Cycle Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Cell Proliferation Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process
Pathways			Translation initiation complex formation Mitotic Prometaphase Separation of Sister Chromatids Peptide chain elongation Mitotic Anaphase M Phase Influenza Life Cycle Formation of the ternary complex, and subsequently, the 43S complex Influenza Viral RNA Transcription and Replication Eukaryotic Translation Initiation Cap-dependent Translation Initiation Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Viral mRNA Translation Influenza Infection L13a-mediated translational silencing of Ceruloplasmin expression Cell Cycle, Mitotic Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Resolution of Sister Chromatid Cohesion Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Mitotic Metaphase and Anaphase Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine) ( 23648065) Subcutaneous adipose tissue ( 22589738)
Protein-Protein Interactions		13 interactors: APOC1 HCFC1R1 NDUFA2 RIF1 RPS27 SERPINH1 SLC35F6 STX18 SUPT4H1 TNNT1 TSPAN6 UCHL3 ZNF768	13 interactors: ACTN1 ACTN4 APC C2orf44 ENOPH1 ENTPD4 HMP19 MARS NACAD PPBP RTN4 SKIL TOM1
Entrez ID		51617	6232
HPRD ID		13664	04744
Ensembl ID		ENSG00000170091	ENSG00000177954
Uniprot IDs		Q9Y328	P42677
PDB IDs			3J3A
Enriched GO Terms of Interacting Partners?			Protein Localization To Tight Junction Tight Junction Assembly Protein Localization To Cell Junction Platelet Degranulation Apical Junction Assembly Regulation Of Cellular Component Movement Cell-cell Junction Assembly Actin Crosslink Formation Platelet Activation Cell Junction Assembly Cell-cell Junction Organization Cellular Component Assembly Cell Activation Actin Filament Bundle Assembly UDP Catabolic Process Vesicle-mediated Transport Regulation Of Apoptotic Process Exocytosis Positive Regulation Of Cellular Component Movement Regulation Of Cell Death Methionyl-tRNA Aminoacylation Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Blood Coagulation Hemostasis Regulation Of Branching Morphogenesis Of A Nerve Positive Regulation Of Pinocytosis Protein Complex Assembly Regulation Of Cell Projection Organization Positive Regulation Of Cell Division Positive Regulation Of Sodium:proton Antiporter Activity Negative Regulation Of Odontogenesis Secretion By Cell Cell Cycle Arrest Regulation Of Sodium:proton Antiporter Activity Peroxisome Proliferator Activated Receptor Signaling Pathway Regulation Of Axonogenesis Regulation Of Body Fluid Levels Regulation Of Cell Migration Metaphase/anaphase Transition Of Mitotic Cell Cycle Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Wound Healing L-methionine Biosynthetic Process From Methylthioadenosine Ribonucleoside Diphosphate Catabolic Process Endoplasmic Reticulum Tubular Network Organization Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process Regulation Of Cell Motility Secretion Nucleoside Diphosphate Catabolic Process L-methionine Salvage Regulation Of Locomotion
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