NSG2 and STX18

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		NSG2	STX18
Description		neuronal vesicle trafficking associated 2	syntaxin 18
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosome Endosome Early Endosome Late Endosome Golgi Apparatus Endosome Membrane Membrane Dendrite Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Early Endosome Membrane Late Endosome Membrane Golgi Cisterna Membrane Multivesicular Body Membrane Trans-Golgi Network Membrane Cell Projection Lysosomal Lumen Postsynaptic Density Membrane Glutamatergic Synapse Golgi Cis Cisterna Membrane	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane SNARE Complex
	Molecular Function	Protein Binding Clathrin Light Chain Binding	SNAP Receptor Activity Protein Binding Protein Domain Specific Binding
	Biological Process	Endosomal Transport Clathrin Coat Assembly Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Protein Transport Vesicle-mediated Transport Membrane Fusion Endoplasmic Reticulum Membrane Organization Positive Regulation Of Organelle Assembly Positive Regulation Of ER To Golgi Vesicle-mediated Transport Regulation Of Golgi Organization
Pathways			COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Alzheimer's disease ( 33074286) Blond vs. brown/black hair color ( 30531825) Diffusing capacity of carbon monoxide ( 30694715) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Chronic rhinosinusitis ( 33393196) Congenital heart disease ( 23708191)
Interacting Genes		17 interacting genes: ANKRD46 APOC1 C3orf52 CLEC7A HCFC1R1 NDUFA2 RIF1 RPS27 RRH SERPINH1 SLC35F6 STX18 SUPT4H1 TNNT1 TSPAN6 UCHL3 ZNF768	6 interacting genes: BNIP1 DISC1 LCOR NSG2 NUPR1 SNCA
Entrez ID		51617	53407
HPRD ID		13664	06923
Ensembl ID		ENSG00000170091	ENSG00000168818
Uniprot IDs		Q9Y328	Q9P2W9
PDB IDs
Enriched GO Terms of Interacting Partners?			Regulation Of Aerobic Respiration Regulation Of Oxidative Phosphorylation Regulation Of Cellular Respiration Kinesin Binding Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Apoptotic Process In Response To Mitochondrial Fragmentation Negative Regulation Of Serotonin Uptake Positive Regulation Of Catabolic Process Transporter Regulator Activity Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Negative Regulation Of Autophagy Positive Regulation Of Hydrogen Peroxide Catabolic Process Negative Regulation Of Chaperone-mediated Autophagy Synaptic Vesicle Regulation Of Generation Of Precursor Metabolites And Energy Negative Regulation Of Type B Pancreatic Cell Proliferation Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Oxidative Phosphorylation Pyramidal Neuron Migration To Cerebral Cortex Central Region Of Growth Cone Calcium-induced Calcium Release Activity Endoplasmic Reticulum Membrane Fusion Negative Regulation Of Dopamine Metabolic Process Molecular Adaptor Activity Cytoplasmic Vesicle Membrane Positive Regulation Of Inflammatory Response Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Perinuclear Region Of Cytoplasm Negative Regulation Of Catecholamine Metabolic Process Regulation Of Serotonin Uptake Golgi Cis Cisterna Membrane Cell Death Negative Regulation Of Programmed Cell Death Programmed Cell Death Apoptotic Process Negative Regulation Of Apoptotic Process Mitochondrial Outer Membrane Presynapse Regulation Of Chaperone-mediated Autophagy Dopamine Uptake Involved In Synaptic Transmission Response To Iron(II) Ion Calcium Ion Homeostasis Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Oxidative Phosphorylation Positive Regulation Of Proteolysis
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