HMP19 and SERPINH1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		HMP19	SERPINH1
Gene Name		HMP19 protein	serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane Cytoplasmic Vesicle Membrane Golgi Cisterna Membrane Multivesicular Body Membrane	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum-Golgi Intermediate Compartment Extracellular Vesicular Exosome
	Molecular Function	Clathrin Light Chain Binding	Serine-type Endopeptidase Inhibitor Activity Collagen Binding Poly(A) RNA Binding Unfolded Protein Binding
	Biological Process	Dopamine Receptor Signaling Pathway Clathrin Coat Assembly	Chondrocyte Development Involved In Endochondral Bone Morphogenesis Response To Unfolded Protein Negative Regulation Of Endopeptidase Activity Extracellular Matrix Organization Collagen Fibril Organization Collagen Biosynthetic Process Protein Maturation
Pathways			Collagen formation Collagen biosynthesis and modifying enzymes
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine) ( 23648065) Subcutaneous adipose tissue ( 22589738)	Height ( 20881960 22021425)
Protein-Protein Interactions		13 interactors: APOC1 HCFC1R1 NDUFA2 RIF1 RPS27 SERPINH1 SLC35F6 STX18 SUPT4H1 TNNT1 TSPAN6 UCHL3 ZNF768	17 interactors: BAG6 BRCA2 C1QL3 CD9 CDK9 CEP70 COL26A1 ESR2 FEZ1 HIST1H1B HMP19 KLF13 PPARG SLC2A4 SLC35F6 UBQLN4 UBTF
Entrez ID		51617	871
HPRD ID		13664	02968
Ensembl ID		ENSG00000170091	ENSG00000149257
Uniprot IDs		Q9Y328	A8K259 P50454
PDB IDs
Enriched GO Terms of Interacting Partners?			Negative Regulation Of DNA Replication DNA-templated Transcription, Initiation Regulation Of Cell Proliferation Negative Regulation Of DNA Metabolic Process Negative Regulation Of Cell Proliferation Regulation Of DNA Replication Cell Maturation Regulation Of Cellular Component Organization Transcription Initiation From RNA Polymerase II Promoter Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Cellular Metabolic Process Brown Fat Cell Differentiation Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Response To Metformin Low-density Lipoprotein Particle Receptor Biosynthetic Process Negative Regulation Of Pancreatic Stellate Cell Proliferation Replication Fork Arrest Response To Diuretic Amylopectin Biosynthetic Process Single Organism Reproductive Process Regulation Of Cellular Process Chromatin Organization Regulation Of Cholesterol Transporter Activity Cellular Response To Vitamin E DNA-templated Transcription, Elongation Reproductive Process Apoptotic Signaling Pathway Regulation Of Cell Growth Brain Development Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Protein Stabilization Macromolecule Biosynthetic Process Head Development Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Multicellular Organism Reproduction Steroid Hormone Mediated Signaling Pathway Meiosis I Membrane Organization DNA-dependent DNA Replication Cellular Response To Oxygen Levels Transcription From RNA Polymerase II Promoter Female Gonad Development Regulation Of Gene Expression Signal Transduction By P53 Class Mediator Development Of Primary Female Sexual Characteristics Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Stress Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation
Tagcloud ?			act biochemical bones caused chaperones consequences deficiency destabilization disorder dominant encode fkbp10 forms genes genetic growing include interact little maturation mislocalization moderately mutant mutation posttranslational predominantly produce reveal secondarily severe
Tagcloud (Difference) ?			act biochemical bones caused chaperones consequences deficiency destabilization disorder dominant encode fkbp10 forms genes genetic growing include interact little maturation mislocalization moderately mutant mutation posttranslational predominantly produce reveal secondarily severe
Tagcloud (Intersection) ?