HMP19 and NDUFA2

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		HMP19	NDUFA2
Gene Name		HMP19 protein	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane Cytoplasmic Vesicle Membrane Golgi Cisterna Membrane Multivesicular Body Membrane	Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I Mitochondrial Membrane
	Molecular Function	Clathrin Light Chain Binding	NADH Dehydrogenase (ubiquinone) Activity
	Biological Process	Dopamine Receptor Signaling Pathway Clathrin Coat Assembly	Mitochondrial Electron Transport, NADH To Ubiquinone Respiratory Electron Transport Chain Cellular Metabolic Process Small Molecule Metabolic Process
Pathways			Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Respiratory electron transport The citric acid (TCA) cycle and respiratory electron transport
Drugs			NADH
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine) ( 23648065) Subcutaneous adipose tissue ( 22589738)
Protein-Protein Interactions		13 interactors: APOC1 HCFC1R1 NDUFA2 RIF1 RPS27 SERPINH1 SLC35F6 STX18 SUPT4H1 TNNT1 TSPAN6 UCHL3 ZNF768	2 interactors: APP HMP19
Entrez ID		51617	4695
HPRD ID		13664	11883
Ensembl ID		ENSG00000170091	ENSG00000131495
Uniprot IDs		Q9Y328	O43678
PDB IDs			1S3A
Enriched GO Terms of Interacting Partners?			Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Clathrin Coat Assembly Dopamine Receptor Signaling Pathway Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Neuron Recognition RNA Polyadenylation Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Vesicle-mediated Transport Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Neuron Apoptotic Process Regulation Of Protein Tyrosine Kinase Activity Visual Learning Glutamate Receptor Signaling Pathway Visual Behavior Neuron Death Platelet Degranulation Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Membrane Budding Cellular Component Assembly Neuromuscular Process Controlling Balance Synapse Assembly MRNA 3'-end Processing Regulation Of ERBB Signaling Pathway Associative Learning Developmental Cell Growth Regulation Of Synapse Structure Or Activity Feeding Behavior Regulation Of Multicellular Organism Growth RNA 3'-end Processing
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