KRT38 and PTGER3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KRT38	PTGER3
Gene Name		keratin 38, type I	prostaglandin E receptor 3 (subtype EP3)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intermediate Filament Extracellular Vesicular Exosome	Nuclear Envelope Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Structural Molecule Activity	Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Prostaglandin E Receptor Activity
	Biological Process		Fever Generation Transcription, DNA-templated G-protein Coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Cell Death Bicarbonate Transport Intracellular Receptor Signaling Pathway Positive Regulation Of Fever Generation Response To Lipopolysaccharide Positive Regulation Of Urine Volume
Pathways			Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR Prostanoid ligand receptors GPCR downstream signaling Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding Eicosanoid ligand-binding receptors
Drugs
Diseases
GWAS
Protein-Protein Interactions		45 interactors: AMOTL2 ANKRD36BP1 BEX2 C19orf57 C1orf216 CCDC146 CD300A CEP57L1 FAM90A1 GLRX3 GNG10 HAUS1 HDAC4 HGS HMG20B HOXA1 KDM1A KLHL38 KRT2 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT79 KRT8 KRT81 KRT83 MAGEB4 PIK3R2 PIN1 PSMA1 PSMC5 PTGER3 RHPN1-AS1 SCNM1 TXLNA TXLNB TXNDC5 USHBP1 ZFYVE21 ZNF20 ZNF417 ZNF587	23 interactors: ADAMTSL4 CCDC33 CDA EFEMP2 INCA1 KRT31 KRT38 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 MEOX2 MGAT5B MKLN1 NOTCH2NL PTGER1 REL RGS17 RGS20 SPRY2 TCF4 TRIM42
Entrez ID		8687	5733
HPRD ID		05176	08906
Ensembl ID		ENSG00000171360	ENSG00000050628
Uniprot IDs		O76015	B1AK19 O00325 P43115
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Protein Sumoylation Epidermis Development Positive Regulation Of Protein Ubiquitination Intermediate Filament Cytoskeleton Organization Abducens Nerve Formation Keratinocyte Activation Negative Regulation Of NK T Cell Activation Regulation Of Primitive Erythrocyte Differentiation Optokinetic Behavior Negative Regulation Of Activation Of JAK2 Kinase Activity Negative Regulation Of Phagocytosis, Engulfment Intermediate Filament-based Process Tissue Development Negative Regulation Of Intracellular Signal Transduction Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of Protein Ubiquitination Transcription, DNA-templated DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Facial Nucleus Development Negative Regulation Of Eosinophil Migration Negative Regulation Of Eosinophil Activation Epithelium Development Negative Regulation Of Signal Transduction Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Cytoskeleton Organization Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle RNA Biosynthetic Process Negative Regulation Of Ubiquitin-protein Transferase Activity	Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Tagcloud ?			accepted acei bdkrb2 cessation combinations converting cough cpn1 digenic epistatic haplotypes hypertensive kinins mme modify monogenic peptidases polymorphisms prostaglandin prostaglandins ptgir ptgis rs11209716 rs2016848 rs4344 rs8012552 substance unresolved xpnpep1
Tagcloud (Difference) ?			accepted acei bdkrb2 cessation combinations converting cough cpn1 digenic epistatic haplotypes hypertensive kinins mme modify monogenic peptidases polymorphisms prostaglandin prostaglandins ptgir ptgis rs11209716 rs2016848 rs4344 rs8012552 substance unresolved xpnpep1
Tagcloud (Intersection) ?