PTGER3

Description		prostaglandin E receptor 3
Image
GO Annotations	Cellular Component	Nuclear Envelope Plasma Membrane Membrane
	Molecular Function	G Protein-coupled Receptor Activity Prostaglandin Receptor Activity Prostaglandin E Receptor Activity Protein Binding
	Biological Process	Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Cell Death Intestine Smooth Muscle Contraction Positive Regulation Of Fever Generation Negative Regulation Of Gastric Acid Secretion
Pathways		Prostanoid ligand receptors G alpha (i) signalling events
Drugs		Bimatoprost Dinoprostone Misoprostol Trichostatin A Gemeprost Limaprost Castor oil Rivenprost
Diseases
GWAS		Alcohol use disorder (consumption score) ( 33861876) Colon cancer ( 33632709) Dental caries (decayed, missing and filled teeth) ( 31533690) Gut microbiota relative abundance (Ruminococcus belonging to family Erysipelotrichaceae) ( 33208821) Intelligence (MTAG) ( 29326435) Proximal colorectal cancer ( 33632709) Verbal declarative memory ( 25648963)
Interacting Genes		23 interacting genes: ADAMTSL4 CCDC33 CDA EFEMP2 INCA1 KRT31 KRT38 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 MEOX2 MGAT5B MKLN1 NOTCH2NLA PTGER1 REL RGS17 RGS20 SPRY2 TCF4 TRIM42
Entrez ID		5733
HPRD ID		08906
Ensembl ID		ENSG00000050628
Uniprot IDs		O00325 P43115
PDB IDs		6AK3 6M9T 7WU9 8GDC
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament Structural Constituent Of Skin Epidermis Intermediate Filament Organization Tissue Morphogenesis Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process
Tagcloud ?