PTGER3 and MKLN1

Number of citations of the paper that reports this interaction (PMID 11006128)
4

Data Source:
BioGRID (pull down)

		PTGER3	MKLN1
Gene Name		prostaglandin E receptor 3 (subtype EP3)	muskelin 1, intracellular mediator containing kelch motifs
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Envelope Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane	Ruffle Cytosol Cell Cortex
	Molecular Function	Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Prostaglandin E Receptor Activity
	Biological Process	Fever Generation Transcription, DNA-templated G-protein Coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Cell Death Bicarbonate Transport Intracellular Receptor Signaling Pathway Positive Regulation Of Fever Generation Response To Lipopolysaccharide Positive Regulation Of Urine Volume	Cell-matrix Adhesion Signal Transduction Regulation Of Cell Shape Actin Cytoskeleton Reorganization
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR Prostanoid ligand receptors GPCR downstream signaling Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding Eicosanoid ligand-binding receptors
Drugs
Diseases
GWAS
Protein-Protein Interactions		23 interactors: ADAMTSL4 CCDC33 CDA EFEMP2 INCA1 KRT31 KRT38 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 MEOX2 MGAT5B MKLN1 NOTCH2NL PTGER1 REL RGS17 RGS20 SPRY2 TCF4 TRIM42	3 interactors: GID8 PTGER3 RANBP9
Entrez ID		5733	4289
HPRD ID		08906	16129
Ensembl ID		ENSG00000050628	ENSG00000128585
Uniprot IDs		B1AK19 O00325 P43115	B4DG30 Q9UL63
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway	Fever Generation Heat Generation Positive Regulation Of Fever Generation Regulation Of Fever Generation Positive Regulation Of Heat Generation Positive Regulation Of Urine Volume Microtubule Nucleation Temperature Homeostasis Microtubule Polymerization Positive Regulation Of Acute Inflammatory Response Bicarbonate Transport Acute-phase Response Microtubule Polymerization Or Depolymerization
Tagcloud ?		accepted acei bdkrb2 cessation combinations converting cough cpn1 digenic epistatic haplotypes hypertensive kinins mme modify monogenic peptidases polymorphisms prostaglandin prostaglandins ptgir ptgis rs11209716 rs2016848 rs4344 rs8012552 substance unresolved xpnpep1	6q arid1a arid1b bclaf1 btg1 clarified cna cnas constituted corresponded cxcr4 deletions delineated foxp1 germline hivep2 hypogammaglobulinemia l265p losses lyn macroglobulinemia myd88 myelokathexis plekhg1 prdm2 recurring waldenstrom wgs wm
Tagcloud (Difference) ?		accepted acei bdkrb2 cessation combinations converting cough cpn1 digenic epistatic haplotypes hypertensive kinins mme modify monogenic peptidases polymorphisms prostaglandin prostaglandins ptgir ptgis rs11209716 rs2016848 rs4344 rs8012552 substance unresolved xpnpep1	6q arid1a arid1b bclaf1 btg1 clarified cna cnas constituted corresponded cxcr4 deletions delineated foxp1 germline hivep2 hypogammaglobulinemia l265p losses lyn macroglobulinemia myd88 myelokathexis plekhg1 prdm2 recurring waldenstrom wgs wm
Tagcloud (Intersection) ?