PTGER3 and PTGER1

Number of citations of the paper that reports this interaction (PubMedID 11235015)
0

Data Source:
HPRD (in vitro)

		PTGER3	PTGER1
Description		prostaglandin E receptor 3	prostaglandin E receptor 1
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Plasma Membrane Membrane	Plasma Membrane Membrane
	Molecular Function	G Protein-coupled Receptor Activity Prostaglandin Receptor Activity Prostaglandin E Receptor Activity Protein Binding	G Protein-coupled Receptor Activity Prostaglandin Receptor Activity Prostaglandin E Receptor Activity D1 Dopamine Receptor Binding
	Biological Process	Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Cell Death Intestine Smooth Muscle Contraction Positive Regulation Of Fever Generation Negative Regulation Of Gastric Acid Secretion	Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Phospholipase C-activating G Protein-coupled Glutamate Receptor Signaling Pathway Response To Lipopolysaccharide Response To Prostaglandin E
Pathways		Prostanoid ligand receptors G alpha (i) signalling events	Prostanoid ligand receptors G alpha (q) signalling events
Drugs		Bimatoprost Dinoprostone Misoprostol Trichostatin A Gemeprost Limaprost Castor oil Rivenprost	Bupivacaine Carboprost tromethamine Alprostadil Bimatoprost Dinoprostone Misoprostol Iloprost Trichostatin A Limaprost Omidenepag isopropyl Rivenprost
Diseases
GWAS		Alcohol use disorder (consumption score) ( 33861876) Colon cancer ( 33632709) Dental caries (decayed, missing and filled teeth) ( 31533690) Gut microbiota relative abundance (Ruminococcus belonging to family Erysipelotrichaceae) ( 33208821) Intelligence (MTAG) ( 29326435) Proximal colorectal cancer ( 33632709) Verbal declarative memory ( 25648963)
Interacting Genes		23 interacting genes: ADAMTSL4 CCDC33 CDA EFEMP2 INCA1 KRT31 KRT38 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 MEOX2 MGAT5B MKLN1 NOTCH2NLA PTGER1 REL RGS17 RGS20 SPRY2 TCF4 TRIM42	5 interacting genes: ADRB2 PTGDS PTGER3 PTGES PTGFR
Entrez ID		5733	5731
HPRD ID		08906	08903
Ensembl ID		ENSG00000050628	ENSG00000160951
Uniprot IDs		O00325 P43115	P34995
PDB IDs		6AK3 6M9T 7WU9 8GDC
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament Structural Constituent Of Skin Epidermis Intermediate Filament Organization Tissue Morphogenesis Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process	Prostaglandin-D Synthase Activity Regulation Of Fever Generation Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Prostaglandin Biosynthetic Process Prostanoid Biosynthetic Process Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Prostaglandin Metabolic Process Prostanoid Metabolic Process Unsaturated Fatty Acid Biosynthetic Process Icosanoid Biosynthetic Process Regulation Of Acute Inflammatory Response G Protein-coupled Receptor Activity Smooth Muscle Contraction Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Positive Regulation Of Mini Excitatory Postsynaptic Potential Unsaturated Fatty Acid Metabolic Process Prostaglandin F Receptor Activity Icosanoid Metabolic Process Fatty Acid Biosynthetic Process Beta2-adrenergic Receptor Activity Norepinephrine-epinephrine-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure G Protein-coupled Receptor Signaling Pathway Beta-adrenergic Receptor Activity Isomerase Activity Negative Regulation Of Male Germ Cell Proliferation Positive Regulation Of Cytosolic Calcium Ion Concentration Prostaglandin-E Synthase Activity Norepinephrine Binding Negative Regulation Of Gastric Acid Secretion Prostaglandin Receptor Activity Intestine Smooth Muscle Contraction Response To Psychosocial Stress Muscle Contraction Positive Regulation Of Lipophagy AMPA Selective Glutamate Receptor Signaling Pathway Regulation Of Male Germ Cell Proliferation Prostaglandin E Receptor Activity Regulation Of Germ Cell Proliferation Positive Regulation Of Fever Generation Cellular Response To Prostaglandin D Stimulus Muscle System Process Positive Regulation Of Autophagosome Maturation Heat Generation Carboxylic Acid Biosynthetic Process Regulation Of Gastric Acid Secretion Adrenergic Receptor Activity Parturition Diet Induced Thermogenesis Negative Regulation Of Multicellular Organismal Process Retinoid Binding
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