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KRT38 and KRT8
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
KRT38
KRT8
Gene Name
keratin 38, type I
keratin 8, type II
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Intermediate Filament
Extracellular Vesicular Exosome
Nucleus
Nucleoplasm
Cytoplasm
Intermediate Filament
Cell-cell Junction
Dystrophin-associated Glycoprotein Complex
Nuclear Matrix
Z Disc
Sarcolemma
Costamere
Keratin Filament
Intermediate Filament Cytoskeleton
Extracellular Vesicular Exosome
Molecular Function
Structural Molecule Activity
Structural Molecule Activity
Protein Binding
Protein Complex Binding
Scaffold Protein Binding
Biological Process
Viral Process
Tumor Necrosis Factor-mediated Signaling Pathway
Sarcomere Organization
Response To Hydrostatic Pressure
Response To Other Organism
Cell Differentiation Involved In Embryonic Placenta Development
Extrinsic Apoptotic Signaling Pathway
Hepatocyte Apoptotic Process
Pathways
Drugs
Diseases
GWAS
Prostate cancer (
21743057
)
Protein-Protein Interactions
45 interactors:
AMOTL2
ANKRD36BP1
BEX2
C19orf57
C1orf216
CCDC146
CD300A
CEP57L1
FAM90A1
GLRX3
GNG10
HAUS1
HDAC4
HGS
HMG20B
HOXA1
KDM1A
KLHL38
KRT2
KRT4
KRT5
KRT6A
KRT6B
KRT6C
KRT71
KRT79
KRT8
KRT81
KRT83
MAGEB4
PIK3R2
PIN1
PSMA1
PSMC5
PTGER3
RHPN1-AS1
SCNM1
TXLNA
TXLNB
TXNDC5
USHBP1
ZFYVE21
ZNF20
ZNF417
ZNF587
35 interactors:
ANXA1
BYSL
DEDD
DMD
EGFR
FBXO25
FGFR3
GRB2
HSPA5
IKBKG
KPNA2
KRT13
KRT15
KRT17
KRT18
KRT31
KRT38
KRT40
MAPK1
MAPK14
MAPK3
MAPK8
PKD1
PKP1
PLAT
PNN
PPL
QRSL1
RAF1
SUMO1
SUMO2
SUMO3
TCHP
TFIP11
TROAP
Entrez ID
8687
3856
HPRD ID
05176
01015
Ensembl ID
ENSG00000171360
ENSG00000170421
Uniprot IDs
O76015
P05787
Q7L4M3
PDB IDs
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Regulation Of Ubiquitin-protein Transferase Activity
Regulation Of Protein Sumoylation
Epidermis Development
Positive Regulation Of Protein Ubiquitination
Intermediate Filament Cytoskeleton Organization
Abducens Nerve Formation
Keratinocyte Activation
Negative Regulation Of NK T Cell Activation
Regulation Of Primitive Erythrocyte Differentiation
Optokinetic Behavior
Negative Regulation Of Activation Of JAK2 Kinase Activity
Negative Regulation Of Phagocytosis, Engulfment
Intermediate Filament-based Process
Tissue Development
Negative Regulation Of Intracellular Signal Transduction
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Regulation Of Protein Ubiquitination
Transcription, DNA-templated
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint
Facial Nucleus Development
Negative Regulation Of Eosinophil Migration
Negative Regulation Of Eosinophil Activation
Epithelium Development
Negative Regulation Of Signal Transduction
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Signal Transduction Involved In DNA Damage Checkpoint
Signal Transduction Involved In Cell Cycle Checkpoint
Cytoskeleton Organization
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
RNA Biosynthetic Process
Negative Regulation Of Ubiquitin-protein Transferase Activity
Neurotrophin TRK Receptor Signaling Pathway
MAPK Cascade
Regulation Of Protein Metabolic Process
Cellular Response To Organic Substance
Neurotrophin Signaling Pathway
Fc-epsilon Receptor Signaling Pathway
Positive Regulation Of Cellular Protein Metabolic Process
Regulation Of Cellular Protein Metabolic Process
Tissue Development
Fc Receptor Signaling Pathway
Signal Transduction By Phosphorylation
Apoptotic Process
Positive Regulation Of Protein Metabolic Process
Programmed Cell Death
Innate Immune Response
Cell Death
Death
Immune Response-regulating Signaling Pathway
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Positive Regulation Of Kinase Activity
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
Immune Response-regulating Cell Surface Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Response To Organic Substance
Positive Regulation Of Transferase Activity
MyD88-dependent Toll-like Receptor Signaling Pathway
Cellular Response To Growth Factor Stimulus
Cellular Response To Lipid
Response To Growth Factor
Anatomical Structure Development
Epidermal Growth Factor Receptor Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Defense Response
Developmental Process
Epithelium Development
Response To Abiotic Stimulus
Regulation Of Immune Response
Positive Regulation Of Protein Kinase Activity
Cellular Response To Fibroblast Growth Factor Stimulus
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Protein Modification Process
Tagcloud
?
ccna1
cdh1
circulatory
code
cohorts
ctnnb1
differentially
erbb2
explain
favorable
gata3
gli1
grouped
hic1
highlighting
interconnected
ipa
jun
mki67
modulate
notch1
predicts
ptgs2
rassf1
regulators
sfn
transducers
trigger
triple
Tagcloud (Difference)
?
ccna1
cdh1
circulatory
code
cohorts
ctnnb1
differentially
erbb2
explain
favorable
gata3
gli1
grouped
hic1
highlighting
interconnected
ipa
jun
mki67
modulate
notch1
predicts
ptgs2
rassf1
regulators
sfn
transducers
trigger
triple
Tagcloud (Intersection)
?