PTGER3 and EFEMP2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PTGER3	EFEMP2
Gene Name		prostaglandin E receptor 3 (subtype EP3)	EGF containing fibulin-like extracellular matrix protein 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Envelope Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane	Extracellular Region Basement Membrane Plasma Membrane Vesicle Extracellular Vesicular Exosome
	Molecular Function	Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Prostaglandin E Receptor Activity	Transmembrane Signaling Receptor Activity Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding
	Biological Process	Fever Generation Transcription, DNA-templated G-protein Coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Cell Death Bicarbonate Transport Intracellular Receptor Signaling Pathway Positive Regulation Of Fever Generation Response To Lipopolysaccharide Positive Regulation Of Urine Volume	Signal Transduction Blood Coagulation Extracellular Matrix Organization
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR Prostanoid ligand receptors GPCR downstream signaling Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding Eicosanoid ligand-binding receptors	Molecules associated with elastic fibres Elastic fibre formation
Drugs
Diseases
GWAS
Protein-Protein Interactions		23 interactors: ADAMTSL4 CCDC33 CDA EFEMP2 INCA1 KRT31 KRT38 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 MEOX2 MGAT5B MKLN1 NOTCH2NL PTGER1 REL RGS17 RGS20 SPRY2 TCF4 TRIM42	50 interactors: APEX2 AQP1 ATN1 ATXN1 ATXN7 BAG6 C5orf24 CACNA1A CATSPER1 CCDC33 CCND3 CCNK COL8A1 CREB5 DGCR6 FAM107A FAM124B FAM74A4 GFI1B GLRX3 HDAC4 HHEX HOXA1 IL16 LCE2D LCE3C LINGO1 MEOX2 NEDD4L NOS3 NUFIP2 PIDD1 PLSCR1 PLSCR4 PTGER3 RBPMS RERE RHOXF2 RHPN1 RIBC2 SGTA SGTB STK16 TCAF1 TP53 UBQLN1 UBQLN4 ZNF263 ZNF426 ZNF638
Entrez ID		5733	30008
HPRD ID		08906	05221
Ensembl ID		ENSG00000050628	ENSG00000172638
Uniprot IDs		B1AK19 O00325 P43115	O95967 Q9H3D5
PDB IDs			2KL7
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway	Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Cellular Process Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Multicellular Organismal Development Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Organ Development Response To Salt Stress Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Cell Death Death Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Biosynthetic Process System Development Developmental Process Phospholipid Scrambling Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Heart Contraction Neuron Death Pons Development Anatomical Structure Development Central Nervous System Development Positive Regulation Of Gene Expression Blood Vessel Development Vasculature Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression
Tagcloud ?		accepted acei bdkrb2 cessation combinations converting cough cpn1 digenic epistatic haplotypes hypertensive kinins mme modify monogenic peptidases polymorphisms prostaglandin prostaglandins ptgir ptgis rs11209716 rs2016848 rs4344 rs8012552 substance unresolved xpnpep1	acaa1 analogous ap1m2 aspirates cgn combat dcn ddr1 deadly ec ecs endometrial eps8l2 fastkd1 gmip ikbke minimally noncarcinoma p2rx4 p4hb phkg2 ppfibp2 ppp1r16a rassf7 rnf183 sirt6 socs2 tjp3 uterine
Tagcloud (Difference) ?		accepted acei bdkrb2 cessation combinations converting cough cpn1 digenic epistatic haplotypes hypertensive kinins mme modify monogenic peptidases polymorphisms prostaglandin prostaglandins ptgir ptgis rs11209716 rs2016848 rs4344 rs8012552 substance unresolved xpnpep1	acaa1 analogous ap1m2 aspirates cgn combat dcn ddr1 deadly ec ecs endometrial eps8l2 fastkd1 gmip ikbke minimally noncarcinoma p2rx4 p4hb phkg2 ppfibp2 ppp1r16a rassf7 rnf183 sirt6 socs2 tjp3 uterine
Tagcloud (Intersection) ?