EIF3J and EIF3K

Number of citations of the paper that reports this interaction (PMID 14519125)
13

Data Source:
HPRD (in vitro)

		EIF3J	EIF3K
Gene Name		eukaryotic translation initiation factor 3, subunit J	eukaryotic translation initiation factor 3, subunit K
Image
Gene Ontology Annotations	Cellular Component	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex	Nucleus Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 3 Complex Membrane Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Extracellular Vesicular Exosome
	Molecular Function	Translation Initiation Factor Activity Protein Binding	Translation Initiation Factor Activity Protein Binding Ribosome Binding
	Biological Process	Formation Of Translation Preinitiation Complex Cytoplasmic Translation Translation Translational Initiation Regulation Of Translational Initiation Gene Expression Cellular Protein Metabolic Process	Formation Of Translation Preinitiation Complex Translation Translational Initiation Regulation Of Translational Initiation Gene Expression Cellular Protein Metabolic Process
Pathways		Ribosomal scanning and start codon recognition Translation initiation complex formation Formation of the ternary complex, and subsequently, the 43S complex GTP hydrolysis and joining of the 60S ribosomal subunit Translation Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Cap-dependent Translation Initiation L13a-mediated translational silencing of Ceruloplasmin expression	Ribosomal scanning and start codon recognition Translation initiation complex formation Formation of the ternary complex, and subsequently, the 43S complex GTP hydrolysis and joining of the 60S ribosomal subunit Translation Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Cap-dependent Translation Initiation L13a-mediated translational silencing of Ceruloplasmin expression
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: CASP3 CSNK2A1 EIF3A EIF3B EIF3C EIF3D EIF3K GNB5 GOLM1 MAGED1 SIAH1 TADA3 TPD52L1	7 interactors: CCND3 EIF3C EIF3G EIF3H EIF3J EIF3L SPP1
Entrez ID		8669	27335
HPRD ID		04883	11740
Ensembl ID		ENSG00000104131	ENSG00000178982
Uniprot IDs		O75822	K7EK53 Q9UBQ5
PDB IDs		2KRB 3BPJ	1RZ4
Enriched GO Terms of Interacting Partners?		Formation Of Translation Preinitiation Complex Regulation Of Translational Initiation Posttranscriptional Regulation Of Gene Expression Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Ribonucleoprotein Complex Assembly Translational Initiation Regulation Of Translation Formation Of Cytoplasmic Translation Initiation Complex Ribonucleoprotein Complex Biogenesis Cytoplasmic Translational Initiation Regulation Of Metabolic Process Cellular Macromolecular Complex Assembly Translation Cytoplasmic Translation Apoptotic Process Programmed Cell Death Cell Death Positive Regulation Of Apoptotic Signaling Pathway Death Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Regulation Of Gene Expression Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Neuron Apoptotic Process Protein Metabolic Process Neuron Death Cellular Protein Metabolic Process Regulation Of Apoptotic Process Regulation Of Cell Death Gene Expression Regulation Of Endopeptidase Activity Cellular Macromolecule Biosynthetic Process Regulation Of Peptidase Activity Macromolecule Biosynthetic Process Regulation Of Cellular Process Regulation Of Protein Phosphorylation Regulation Of Tubulin Deacetylation Cellular Component Assembly Regulation Of Protein Stability Negative Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Metabolic Process Glial Cell Apoptotic Process Positive Regulation Of Signal Transduction Regulation Of Apoptotic DNA Fragmentation Regulation Of Phosphorylation Mature Ribosome Assembly Cell Cycle	Formation Of Translation Preinitiation Complex Regulation Of Translational Initiation Ribonucleoprotein Complex Assembly Translational Initiation Regulation Of Translation Ribonucleoprotein Complex Biogenesis Posttranscriptional Regulation Of Gene Expression Cellular Macromolecular Complex Assembly Translation Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Cellular Component Assembly Cellular Protein Metabolic Process Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Protein Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Collateral Sprouting Negative Regulation Of Axon Regeneration Cytoplasmic Translation Positive Regulation Of Bone Resorption Biosynthetic Process Regulation Of Metabolic Process Regulation Of Gene Expression Regulation Of Axon Regeneration Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Cellular Process Positive Regulation Of Tissue Remodeling Decidualization Response To Vitamin D Regulation Of Bone Resorption Maternal Placenta Development Regulation Of Bone Remodeling
Tagcloud ?		3a apart bindings binds carboxyl concurrently consisting docking eif3a eif3b eif3g eif3i exclusive exist indirectly mutually noncanonical participates perform purification solved spectrin subcomplex subcomplexes tandem translation translational tumorigenesis	abundances bovine caprine carcasses carefully cd36 cln3 concentrate degradable erased genorm misinterpretation mrpl39 normalisation normalising partitioning ppia productions profitability rankings reference rplp0 ruminant ruminants sets sunflower tbp top2b uxt
Tagcloud (Difference) ?		3a apart bindings binds carboxyl concurrently consisting docking eif3a eif3b eif3g eif3i exclusive exist indirectly mutually noncanonical participates perform purification solved spectrin subcomplex subcomplexes tandem translation translational tumorigenesis	abundances bovine caprine carcasses carefully cd36 cln3 concentrate degradable erased genorm misinterpretation mrpl39 normalisation normalising partitioning ppia productions profitability rankings reference rplp0 ruminant ruminants sets sunflower tbp top2b uxt
Tagcloud (Intersection) ?