EIF3J and TPD52L1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EIF3J	TPD52L1
Gene Name		eukaryotic translation initiation factor 3, subunit J	tumor protein D52-like 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex	Cytoplasm Perinuclear Region Of Cytoplasm
	Molecular Function	Translation Initiation Factor Activity Protein Binding	Protein Binding Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	Formation Of Translation Preinitiation Complex Cytoplasmic Translation Translation Translational Initiation Regulation Of Translational Initiation Gene Expression Cellular Protein Metabolic Process	G2/M Transition Of Mitotic Cell Cycle Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of MAP Kinase Activity Positive Regulation Of JNK Cascade Positive Regulation Of Apoptotic Signaling Pathway
Pathways		Ribosomal scanning and start codon recognition Translation initiation complex formation Formation of the ternary complex, and subsequently, the 43S complex GTP hydrolysis and joining of the 60S ribosomal subunit Translation Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Cap-dependent Translation Initiation L13a-mediated translational silencing of Ceruloplasmin expression	Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: CASP3 CSNK2A1 EIF3A EIF3B EIF3C EIF3D EIF3K GNB5 GOLM1 MAGED1 SIAH1 TADA3 TPD52L1	13 interactors: ABL2 EIF3J GPR135 HDAC1 MAL2 MAP3K5 PAK6 TPD52 TPD52L2 TPD52L3 YAE1D1 YWHAB YWHAZ
Entrez ID		8669	7164
HPRD ID		04883	07236
Ensembl ID		ENSG00000104131	ENSG00000111907
Uniprot IDs		O75822	E9PPQ1 F6V707 J3KNE7 Q16890
PDB IDs		2KRB 3BPJ
Enriched GO Terms of Interacting Partners?		Formation Of Translation Preinitiation Complex Regulation Of Translational Initiation Posttranscriptional Regulation Of Gene Expression Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Ribonucleoprotein Complex Assembly Translational Initiation Regulation Of Translation Formation Of Cytoplasmic Translation Initiation Complex Ribonucleoprotein Complex Biogenesis Cytoplasmic Translational Initiation Regulation Of Metabolic Process Cellular Macromolecular Complex Assembly Translation Cytoplasmic Translation Apoptotic Process Programmed Cell Death Cell Death Positive Regulation Of Apoptotic Signaling Pathway Death Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Regulation Of Gene Expression Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Neuron Apoptotic Process Protein Metabolic Process Neuron Death Cellular Protein Metabolic Process Regulation Of Apoptotic Process Regulation Of Cell Death Gene Expression Regulation Of Endopeptidase Activity Cellular Macromolecule Biosynthetic Process Regulation Of Peptidase Activity Macromolecule Biosynthetic Process Regulation Of Cellular Process Regulation Of Protein Phosphorylation Regulation Of Tubulin Deacetylation Cellular Component Assembly Regulation Of Protein Stability Negative Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Metabolic Process Glial Cell Apoptotic Process Positive Regulation Of Signal Transduction Regulation Of Apoptotic DNA Fragmentation Regulation Of Phosphorylation Mature Ribosome Assembly Cell Cycle	Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Apoptotic Process Signal Transduction By Phosphorylation Regulation Of Cell Death Positive Regulation Of Mitochondrion Organization Apoptotic Signaling Pathway Activation Of MAPKK Activity Apoptotic Process Phosphorylation Programmed Cell Death Cell Death Death Regulation Of Mitochondrion Organization Positive Regulation Of MAPK Cascade Leukocyte Activation Immune System Process Regulation Of Cellular Process Positive Regulation Of Signal Transduction Immune Response Defense Response Signal Transduction Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Golgi Reassembly Positive Regulation Of Interferon-gamma Secretion Positive Regulation Of Cell Death Regulation Of MAPK Cascade Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Cell Proliferation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Activation Regulation Of Establishment Of Protein Localization Negative Regulation Of Protein Dephosphorylation Histamine Secretion By Mast Cell Signaling Cell Communication Establishment Of Golgi Localization Positive Regulation Of Transport Positive Regulation Of Apoptotic Signaling Pathway Bergmann Glial Cell Differentiation Golgi Inheritance Regulation Of Signal Transduction Neurotrophin TRK Receptor Signaling Pathway Regulation Of Protein Localization Phosphate-containing Compound Metabolic Process Neurotrophin Signaling Pathway
Tagcloud ?		3a apart bindings binds carboxyl concurrently consisting docking eif3a eif3b eif3g eif3i exclusive exist indirectly mutually noncanonical participates perform purification solved spectrin subcomplex subcomplexes tandem translation translational tumorigenesis	abcf2 adprtl1 amy2b arhgap4 atp6ap1 axin1 casp4 cox1 cox7b ctsl etv4 lgals3bp mgc35136 mgc5528 mt2a mt3 ngfrap1 p53scv ppia prdx2 psap scgb2a2 smoc2 sptan1 sra1 tax1bp1 tra1 trf4 tuba4
Tagcloud (Difference) ?		3a apart bindings binds carboxyl concurrently consisting docking eif3a eif3b eif3g eif3i exclusive exist indirectly mutually noncanonical participates perform purification solved spectrin subcomplex subcomplexes tandem translation translational tumorigenesis	abcf2 adprtl1 amy2b arhgap4 atp6ap1 axin1 casp4 cox1 cox7b ctsl etv4 lgals3bp mgc35136 mgc5528 mt2a mt3 ngfrap1 p53scv ppia prdx2 psap scgb2a2 smoc2 sptan1 sra1 tax1bp1 tra1 trf4 tuba4
Tagcloud (Intersection) ?