EIF3K

Gene Name		eukaryotic translation initiation factor 3, subunit K
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Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 3 Complex Membrane Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Extracellular Vesicular Exosome
	Molecular Function	Translation Initiation Factor Activity Protein Binding Ribosome Binding
	Biological Process	Formation Of Translation Preinitiation Complex Translation Translational Initiation Regulation Of Translational Initiation Gene Expression Cellular Protein Metabolic Process
Pathways		Ribosomal scanning and start codon recognition Translation initiation complex formation Formation of the ternary complex, and subsequently, the 43S complex GTP hydrolysis and joining of the 60S ribosomal subunit Translation Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Cap-dependent Translation Initiation L13a-mediated translational silencing of Ceruloplasmin expression
Drugs
Diseases
GWAS
Protein-protein Interactions		7 interactors: CCND3 EIF3C EIF3G EIF3H EIF3J EIF3L SPP1
Entrez ID		27335
HPRD ID		11740
Ensembl ID		ENSG00000178982
Uniprot IDs		K7EK53 Q9UBQ5
PDB IDs		1RZ4
Enriched GO Terms of Interacting Partners?		Formation Of Translation Preinitiation Complex Regulation Of Translational Initiation Ribonucleoprotein Complex Assembly Translational Initiation Regulation Of Translation Ribonucleoprotein Complex Biogenesis Posttranscriptional Regulation Of Gene Expression Cellular Macromolecular Complex Assembly Translation Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Cellular Component Assembly Cellular Protein Metabolic Process Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Protein Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Collateral Sprouting Negative Regulation Of Axon Regeneration Cytoplasmic Translation Positive Regulation Of Bone Resorption Biosynthetic Process Regulation Of Metabolic Process Regulation Of Gene Expression Regulation Of Axon Regeneration Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Cellular Process Positive Regulation Of Tissue Remodeling Decidualization Response To Vitamin D Regulation Of Bone Resorption Maternal Placenta Development Regulation Of Bone Remodeling
Tagcloud ?		abundances bovine caprine carcasses carefully cd36 cln3 concentrate degradable erased genorm misinterpretation mrpl39 normalisation normalising partitioning ppia productions profitability rankings reference rplp0 ruminant ruminants sets sunflower tbp top2b uxt