EIF3K and EIF3J

Number of citations of the paper that reports this interaction (PubMedID 14519125)
0

Data Source:
HPRD (in vitro)

		EIF3K	EIF3J
Description		eukaryotic translation initiation factor 3 subunit K	eukaryotic translation initiation factor 3 subunit J
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 3 Complex Membrane Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex	Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex
	Molecular Function	RNA Binding Translation Initiation Factor Activity Protein Binding Ribosome Binding	Translation Initiation Factor Activity Protein Binding Identical Protein Binding
	Biological Process	Formation Of Cytoplasmic Translation Initiation Complex Cytoplasmic Translational Initiation Translation Translational Initiation Regulation Of Translational Initiation	Formation Of Cytoplasmic Translation Initiation Complex Cytoplasmic Translational Initiation Translation Translational Initiation
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit	L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545)	Anti-Toxoplasma gondii IgG seropositivity ( 30610941)
Interacting Genes		7 interacting genes: CCND3 EIF3C EIF3G EIF3H EIF3J EIF3L SPP1	16 interacting genes: ABCE1 CASP3 CSNK2A1 EIF3A EIF3B EIF3C EIF3D EIF3K GNB5 GOLM1 MAGED1 METTL3 NFE2L2 SIAH1 TADA3 TPD52L1
Entrez ID		27335	8669
HPRD ID		11740	04883
Ensembl ID		ENSG00000178982	ENSG00000104131
Uniprot IDs		K7EK53 K7ERF1 Q9UBQ5 U3LUI4	O75822
PDB IDs		1RZ4 3J8B 3J8C 6FEC 6YBD 6ZMW 6ZON 6ZP4 6ZVJ 7A09 7QP6 7QP7 8OZ0 8PJ1 8PJ2 8PJ3 8PJ4 8PJ5 8PJ6 8PPL 8RG0 8XXN 9BLN	2KRB 3BPJ 6YBW 6ZMW 6ZVJ
Enriched GO Terms of Interacting Partners?		Formation Of Cytoplasmic Translation Initiation Complex Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 48S Preinitiation Complex Eukaryotic 43S Preinitiation Complex Cytoplasmic Translational Initiation Translation Initiation Factor Activity Translational Initiation Protein-RNA Complex Assembly Translation Viral Translational Termination-reinitiation Protein-containing Complex Assembly Protein-containing Complex Organization Macromolecule Biosynthetic Process Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Cyclin D3-CDK6 Complex Cyclin D3-CDK4 Complex Positive Regulation Of Estradiol Secretion Cellular Component Assembly Regulation Of Estradiol Secretion Viral Process RNA Binding Androgen Catabolic Process Protein Metabolic Process Cellular Response To Testosterone Stimulus Eukaryotic Translation Initiation Factor 3 Complex, EIF3m Response To 2,3,7,8-tetrachlorodibenzodioxine Response To Macrophage Colony-stimulating Factor Cyclin-dependent Protein Serine/threonine Kinase Activator Activity Cytosol Positive Regulation Of Bone Resorption Negative Regulation Of Collateral Sprouting Negative Regulation Of Axon Regeneration Negative Regulation Of Neuron Projection Regeneration Metal-dependent Deubiquitinase Activity Hormone Catabolic Process	Formation Of Cytoplasmic Translation Initiation Complex Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 48S Preinitiation Complex Eukaryotic 43S Preinitiation Complex Translational Initiation Cytoplasmic Translational Initiation Translation Initiation Factor Activity Viral Translational Termination-reinitiation Eukaryotic Translation Initiation Factor 3 Complex, EIF3m IRES-dependent Viral Translational Initiation Translation Protein-RNA Complex Assembly Regulation Of Translation Regulation Of Protein Metabolic Process Regulation Of Translational Initiation Post-transcriptional Regulation Of Gene Expression Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Protein Metabolic Process Protein Metabolic Process Cytosol Rhythmic Process Regulation Of Hematopoietic Stem Cell Differentiation Regulation Of Primary Metabolic Process Macromolecule Biosynthetic Process Protein Catabolic Process Translation Initiation Factor Binding Execution Phase Of Apoptosis Regulation Of Protein Stability Positive Regulation Of Apoptotic Signaling Pathway Viral Process Positive Regulation Of Amide Metabolic Process Regulation Of Hematopoietic Progenitor Cell Differentiation Macromolecule Metabolic Process Positive Regulation Of Glutathione Biosynthetic Process Negative Regulation Of Endoribonuclease Activity GTPase Activator Complex G-protein Gamma-subunit Binding Cytoplasm Protein-containing Complex Organization Regulation Of Metabolic Process Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Programmed Cell Death Phospholipase A2 Activator Activity Regulation Of Glutathione Biosynthetic Process Aflatoxin Catabolic Process Endoribonuclease Inhibitor Activity Regulation Of Endoribonuclease Activity RNA Binding
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