EIF3J and GOLM1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EIF3J	GOLM1
Gene Name		eukaryotic translation initiation factor 3, subunit J	golgi membrane protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex	Extracellular Space Golgi Apparatus Integral Component Of Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Translation Initiation Factor Activity Protein Binding	Protein Binding
	Biological Process	Formation Of Translation Preinitiation Complex Cytoplasmic Translation Translation Translational Initiation Regulation Of Translational Initiation Gene Expression Cellular Protein Metabolic Process	Nucleus Organization Regulation Of Lipid Metabolic Process
Pathways		Ribosomal scanning and start codon recognition Translation initiation complex formation Formation of the ternary complex, and subsequently, the 43S complex GTP hydrolysis and joining of the 60S ribosomal subunit Translation Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Cap-dependent Translation Initiation L13a-mediated translational silencing of Ceruloplasmin expression
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: CASP3 CSNK2A1 EIF3A EIF3B EIF3C EIF3D EIF3K GNB5 GOLM1 MAGED1 SIAH1 TADA3 TPD52L1	26 interactors: B3GNT4 C1orf174 CIAO1 CLK1 DCK DCTN2 DEXI EFTUD2 EIF2B3 EIF3J ELAC2 FLOT1 FTH1 GEMIN7 GNB2L1 GRIK5 KCNE3 LSM12 MED22 NIPSNAP3A NRSN2 RPA2 RPL13A SLC40A1 SYT1 ZFAND3
Entrez ID		8669	51280
HPRD ID		04883	08428
Ensembl ID		ENSG00000104131	ENSG00000135052
Uniprot IDs		O75822	B3KNK9 Q8NBJ4
PDB IDs		2KRB 3BPJ
Enriched GO Terms of Interacting Partners?		Formation Of Translation Preinitiation Complex Regulation Of Translational Initiation Posttranscriptional Regulation Of Gene Expression Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Ribonucleoprotein Complex Assembly Translational Initiation Regulation Of Translation Formation Of Cytoplasmic Translation Initiation Complex Ribonucleoprotein Complex Biogenesis Cytoplasmic Translational Initiation Regulation Of Metabolic Process Cellular Macromolecular Complex Assembly Translation Cytoplasmic Translation Apoptotic Process Programmed Cell Death Cell Death Positive Regulation Of Apoptotic Signaling Pathway Death Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Regulation Of Gene Expression Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Neuron Apoptotic Process Protein Metabolic Process Neuron Death Cellular Protein Metabolic Process Regulation Of Apoptotic Process Regulation Of Cell Death Gene Expression Regulation Of Endopeptidase Activity Cellular Macromolecule Biosynthetic Process Regulation Of Peptidase Activity Macromolecule Biosynthetic Process Regulation Of Cellular Process Regulation Of Protein Phosphorylation Regulation Of Tubulin Deacetylation Cellular Component Assembly Regulation Of Protein Stability Negative Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Metabolic Process Glial Cell Apoptotic Process Positive Regulation Of Signal Transduction Regulation Of Apoptotic DNA Fragmentation Regulation Of Phosphorylation Mature Ribosome Assembly Cell Cycle	Regulation Of Translational Initiation Negative Regulation Of Translation Regulation Of Translation Negative Regulation Of Translational Initiation Regulation Of Vesicle Fusion Posttranscriptional Regulation Of Gene Expression Mitochondrial TRNA 3'-trailer Cleavage, Endonucleolytic Negative Regulation Of Formation Of Translation Preinitiation Complex Fast, Calcium Ion-dependent Exocytosis Of Neurotransmitter Spleen Trabecula Formation Translational Initiation Intracellular Sequestering Of Iron Ion TRNA 3'-trailer Cleavage Positive Regulation Of CAMP Catabolic Process Iron Ion Transport Cellular Iron Ion Homeostasis Dicarboxylic Acid Transport Negative Regulation Of Hydrogen Peroxide-induced Neuron Death Mitochondrial RNA 3'-end Processing Cellular Homeostasis
Tagcloud ?		3a apart bindings binds carboxyl concurrently consisting docking eif3a eif3b eif3g eif3i exclusive exist indirectly mutually noncanonical participates perform purification solved spectrin subcomplex subcomplexes tandem translation translational tumorigenesis	16q 1q affymetrix classic clustering clusters cytoskeleton distinguished epithelium fresh frozen gpr137b hierarchical ilc lcis lobular mastectomy microarrays microdissected obligate personalize pik3r1 precursor prophylactic supervised transcriptomic triplets u133a unsupervised
Tagcloud (Difference) ?		3a apart bindings binds carboxyl concurrently consisting docking eif3a eif3b eif3g eif3i exclusive exist indirectly mutually noncanonical participates perform purification solved spectrin subcomplex subcomplexes tandem translation translational tumorigenesis	16q 1q affymetrix classic clustering clusters cytoskeleton distinguished epithelium fresh frozen gpr137b hierarchical ilc lcis lobular mastectomy microarrays microdissected obligate personalize pik3r1 precursor prophylactic supervised transcriptomic triplets u133a unsupervised
Tagcloud (Intersection) ?