DAZ1 and DAZL

Number of citations of the paper that reports this interaction (PMID 12511597)
43

Data Source:
BioGRID (two hybrid, pull down, two hybrid)
HPRD (in vitro)

		DAZ1	DAZL
Gene Name		deleted in azoospermia 1	deleted in azoospermia-like
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Cytoplasm Polysome
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding Translation Activator Activity	Nucleotide Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Translation Activator Activity Identical Protein Binding
	Biological Process	Multicellular Organismal Development Spermatogenesis Cell Differentiation Positive Regulation Of Translational Initiation	Oocyte Maturation Female Meiosis II Multicellular Organismal Development Germ Cell Development Spermatogenesis Positive Regulation Of Meiotic Nuclear Division Positive Regulation Of Translational Initiation
Pathways
Drugs
Diseases
GWAS			Testicular germ cell tumor ( 23666240)
Protein-Protein Interactions		10 interactors: BOLL DAZAP1 DAZAP2 DAZL DYNLL1 DZIP1 DZIP1L DZIP3 PUM2 QKI	5 interactors: DAZ1 DAZ4 DAZAP1 DAZAP2 PUM2
Entrez ID		1617	1618
HPRD ID		15958	09029
Ensembl ID		ENSG00000188120	ENSG00000092345
Uniprot IDs		Q1RMF9 Q86SG3 Q9NQZ3	Q92904
PDB IDs
Enriched GO Terms of Interacting Partners?		Gamete Generation Sexual Reproduction Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Spermatogenesis Male Gamete Generation Reproduction Single Organism Reproductive Process Regulation Of Translation Reproductive Process Positive Regulation Of Translational Initiation Posttranscriptional Regulation Of Gene Expression Developmental Process Involved In Reproduction Germ Cell Development Organelle Organization Regulation Of Translational Initiation Positive Regulation Of Translation Female Meiosis II Organelle Assembly 3'-UTR-mediated MRNA Destabilization Female Gamete Generation Developmental Process Positive Regulation Of Gene Expression Meiotic Nuclear Division Cilium Assembly Cilium Organization MRNA Destabilization Meiotic Cell Cycle Cilium Morphogenesis Multicellular Organismal Development Regulation Of Gene Expression Anatomical Structure Development RNA Destabilization Regulation Of Cellular Protein Metabolic Process Cell Differentiation Cell Projection Assembly Stress Granule Assembly Long-chain Fatty Acid Biosynthetic Process Regulation Of Protein Metabolic Process Positive Regulation Of Meiotic Nuclear Division Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Anatomical Structure Morphogenesis Oocyte Maturation Positive Regulation Of Organelle Organization Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of MRNA Splicing, Via Spliceosome Cell Cycle Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of RNA Splicing Female Meiotic Division	Spermatogenesis Male Gamete Generation Gamete Generation Sexual Reproduction Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Reproduction Single Organism Reproductive Process Reproductive Process Regulation Of Translation Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Translational Initiation Stress Granule Assembly Positive Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of RNA Splicing Maternal Placenta Development Cell Differentiation Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Translational Initiation Positive Regulation Of Translation Maternal Process Involved In Female Pregnancy Regulation Of MRNA Processing Regulation Of RNA Splicing
Tagcloud ?		cfsdna clpb coincident detecting dnmt3l epididymis fragments gml hoxa5 medip methylated methylation morc1 msh4 normozoospermia nz obviously peg10 prame promoters pv qpcr quantitatively semen seminal snurf testis ultrasonication vasectomy	122c 2012cb944901 9qh azoospermia blimp1 ddx4 declare dppa3 envisioned fam122c funds grants hef ikbkg ipsc ipscs lin28 poi poi1 poi2 prdm1 q26 rbmx stella sublines talents vasa xq znf
Tagcloud (Difference) ?		cfsdna clpb coincident detecting dnmt3l epididymis fragments gml hoxa5 medip methylated methylation morc1 msh4 normozoospermia nz obviously peg10 prame promoters pv qpcr quantitatively semen seminal snurf testis ultrasonication vasectomy	122c 2012cb944901 9qh azoospermia blimp1 ddx4 declare dppa3 envisioned fam122c funds grants hef ikbkg ipsc ipscs lin28 poi poi1 poi2 prdm1 q26 rbmx stella sublines talents vasa xq znf
Tagcloud (Intersection) ?