RUNX3 and HDAC5

  • Number of citations of the paper that reports this interaction (PMID 15138260)
  • 42
  • Data Source:
  • HPRD (in vitro, in vivo)

RUNX3

HDAC5

Gene Name runt-related transcription factor 3 histone deacetylase 5
Image No pdb structure No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Bone mineral density (hip) ( 19801982)
  • Bone mineral density (spine) ( 19801982)
Protein-Protein Interactions 13 interactors: CBFB EP300 HDAC1 HDAC2 HDAC4 HDAC5 NOTCH1 SMAD3 SMURF1 SMURF2 SP110 TLE1 YAP1 59 interactors: ANKRA2 ANKRD11 ATF3 BCL6 BCOR BRMS1 CAMK1 CAMTA2 CBX5 CIITA CTBP1 DDX20 DYRK1B EEF1G ESR1 GABARAP GATA1 GATA2 GCM1 GNB1 HDAC3 HDAC7 HIF1A HOXC11 HR JDP2 KLF4 MAFF MEF2A MEF2C MEF2D NCOR1 NCOR2 NFATC1 NFKB2 NFKBIE NRIP1 PHB2 PKN1 PKN2 PRKAA1 PRKCD PRKD1 RFXANK RUNX3 SFN SIK1 SIK2 SIK3 SLC2A4RG SMAD3 SUV39H1 TAB2 UBC UBE2I YWHAB YWHAE YWHAQ ZBTB16
Entrez ID 864 10014
HPRD ID 02565 09246
Ensembl ID ENSG00000020633 ENSG00000108840
Uniprot IDs Q13761 Q9UQL6
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
1q22  aml  correlative  cytogenetic  decitabine  demethylating  elucidate  epigenetics  frequent  haematological  hypermethylation  inactivation  inv  leukaemia  leukaemias  lymphocytic  malignancies  methylated  mostly  myelodysplatic  p13  promoters  re  relapse  runx1  runx2  syndromes  unmethylated 
125a  5p  activating  anticancer  apoptosis  converse  deacetylase  detailed  doi  downregulation  exist  hdaci  implications  induce  intrinsic  involving  loop  mediates  microrna  mir  mt  nevertheless  runx3  silenced  silencing  subsequently  transcriptionally  tumorigenesis 
Tagcloud (Difference) ?
1q22  aml  correlative  cytogenetic  decitabine  demethylating  elucidate  epigenetics  frequent  haematological  hypermethylation  inactivation  inv  leukaemia  leukaemias  lymphocytic  malignancies  methylated  mostly  myelodysplatic  p13  promoters  re  relapse  runx1  runx2  syndromes  unmethylated 
125a  5p  activating  anticancer  apoptosis  converse  deacetylase  detailed  doi  downregulation  exist  hdaci  implications  induce  intrinsic  involving  loop  mediates  microrna  mir  mt  nevertheless  silenced  silencing  subsequently  transcriptionally  tumorigenesis 
Tagcloud (Intersection) ?
runx3