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SKAP1 and SH2D4A
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
SKAP1
SH2D4A
Gene Name
src kinase associated phosphoprotein 1
SH2 domain containing 4A
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Plasma Membrane
Cell-cell Junction
Cytoplasm
Molecular Function
SH3/SH2 Adaptor Activity
Protein Binding
SH3 Domain Binding
Protein Kinase Binding
Protein Phosphatase Binding
Protein Complex Binding
SH2 Domain Binding
Protein Binding
Phosphatase Binding
Biological Process
Positive Regulation Of Signal Transduction
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
T Cell Receptor Signaling Pathway
Negative Regulation Of Phosphatase Activity
Pathways
Drugs
Diseases
GWAS
Epilepsy (generalized) (
22949513
)
Ovarian cancer (
20852632
)
Protein-Protein Interactions
12 interactors:
APP
BLCAP
FAM102A
FYB
FYN
GRB2
LCK
LYN
PRAM1
PTPRC
SH2D4A
SRC
43 interactors:
ALAS1
CASK
CCDC172
CDR2
CEP70
CEP76
DBNL
FSD2
GOLGA2
GRB2
HCLS1
HMBOX1
IKZF1
KRT40
LDOC1
LZTS2
MAGEA11
MAGEA6
MTUS2
NECAB2
NINL
NUTM1
PDE4DIP
PNMA1
PPP1CB
PSTPIP1
RINT1
SH3GL1
SKAP1
SORBS2
SORBS3
SPAG5
STAM2
STX11
TACC1
TFIP11
TRAF2
TRIM23
TRIM27
UBXN11
USHBP1
VPS52
ZBTB16
Entrez ID
8631
63898
HPRD ID
05396
08340
Ensembl ID
ENSG00000141293
ENSG00000104611
Uniprot IDs
Q86WV1
Q9H788
PDB IDs
1U5D
Enriched GO Terms of Interacting Partners
?
Immune Response-activating Cell Surface Receptor Signaling Pathway
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Platelet Activation
T Cell Costimulation
Positive Regulation Of T Cell Activation
Positive Regulation Of Homotypic Cell-cell Adhesion
Immune Response-regulating Signaling Pathway
Positive Regulation Of Cell-cell Adhesion
Regulation Of T Cell Activation
Positive Regulation Of Cell Activation
Positive Regulation Of Immune Response
Antigen Receptor-mediated Signaling Pathway
Peptidyl-tyrosine Autophosphorylation
Cell Activation
Regulation Of Cell-cell Adhesion
Positive Regulation Of Cell Adhesion
Regulation Of Lymphocyte Activation
Axon Guidance
Blood Coagulation
Hemostasis
Regulation Of Immune Response
Regulation Of Cell Activation
Positive Regulation Of Immune System Process
Leukocyte Migration
Axonogenesis
Axon Development
Regulation Of Body Fluid Levels
Cell Morphogenesis Involved In Neuron Differentiation
Response To Abiotic Stimulus
Fc Receptor Signaling Pathway
Wound Healing
Chemotaxis
Regulation Of Cell Adhesion
Neuron Projection Morphogenesis
T Cell Receptor Signaling Pathway
Cellular Response To Peptide Hormone Stimulus
Cellular Response To Peptide
Locomotion
Response To Wounding
Positive Regulation Of Antigen Receptor-mediated Signaling Pathway
Cell Morphogenesis Involved In Differentiation
Immune Response
Regulation Of Immune System Process
Immune System Process
Defense Response
Innate Immune Response
Neuron Projection Development
Cell Migration
Cell Projection Morphogenesis
Regulation Of Phosphorus Metabolic Process
Cell Cycle
Positive Regulation Of NK T Cell Differentiation
G2/M Transition Of Mitotic Cell Cycle
Organelle Organization
Regulation Of Cytoskeleton Organization
Positive Regulation Of Granulocyte Differentiation
Mitotic Cell Cycle
Immune System Process
Positive Regulation Of Cytoskeleton Organization
Regulation Of Cell Adhesion
Positive Regulation Of T Cell Activation
Positive Regulation Of Homotypic Cell-cell Adhesion
Cell Division
Mitotic Cell Cycle Process
Positive Regulation Of Cell-cell Adhesion
Protein Complex Assembly
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Regulation Of Calcium Ion Import
Actin Filament Organization
Regulation Of T Cell Activation
Cytoskeleton Organization
Positive Regulation Of Cell Activation
Protein K63-linked Ubiquitination
Protein Trimerization
Cellular Protein Complex Assembly
Positive Regulation Of Immune System Process
Regulation Of Organelle Organization
Regulation Of Microtubule-based Process
Positive Regulation Of Neutrophil Differentiation
Spliceosomal Complex Disassembly
Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint
Regulation Of Actin Cytoskeleton Organization
Regulation Of Cell-cell Adhesion
Positive Regulation Of Cell Adhesion
Positive Regulation Of Alpha-beta T Cell Differentiation
Regulation Of Immune System Process
Regulation Of Myeloid Cell Differentiation
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of Actin Filament Polymerization
Positive Regulation Of Cellular Metabolic Process
Regulation Of Lymphocyte Activation
Negative Regulation Of ERBB Signaling Pathway
Positive Regulation Of Organelle Organization
Regulation Of Actin Filament-based Process
Positive Regulation Of Myeloid Leukocyte Differentiation
Regulation Of Cellular Localization
Cell Cycle Process
Regulation Of Actin Polymerization Or Depolymerization
Regulation Of Actin Filament Length
Tagcloud
?
10kb
appbp2
arhgap32
bcas3
breakpoints
ccdc49
coamplification
col14a1
coregulator
ddx5
depdc6
deptor
enpp2
hoxb9
lasp1
leukaemias
nrip1
oprd1
painting
pcgf2
phf20l1
plec1
taok1
tiam1
timm23
trps1
unamplified
usp32
zmym4
Tagcloud (Difference)
?
10kb
appbp2
arhgap32
bcas3
breakpoints
ccdc49
coamplification
col14a1
coregulator
ddx5
depdc6
deptor
enpp2
hoxb9
lasp1
leukaemias
nrip1
oprd1
painting
pcgf2
phf20l1
plec1
taok1
tiam1
timm23
trps1
unamplified
usp32
zmym4
Tagcloud (Intersection)
?