SKAP1

Gene Name		src kinase associated phosphoprotein 1
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Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Cell-cell Junction
	Molecular Function	SH3/SH2 Adaptor Activity Protein Binding SH3 Domain Binding Protein Kinase Binding Protein Phosphatase Binding Protein Complex Binding SH2 Domain Binding
	Biological Process	Positive Regulation Of Signal Transduction Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter T Cell Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Epilepsy (generalized) ( 22949513) Ovarian cancer ( 20852632)
Protein-protein Interactions		12 interactors: APP BLCAP FAM102A FYB FYN GRB2 LCK LYN PRAM1 PTPRC SH2D4A SRC
Entrez ID		8631
HPRD ID		05396
Ensembl ID		ENSG00000141293
Uniprot IDs		Q86WV1
PDB IDs		1U5D
Enriched GO Terms of Interacting Partners?		Immune Response-activating Cell Surface Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Platelet Activation T Cell Costimulation Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Immune Response-regulating Signaling Pathway Positive Regulation Of Cell-cell Adhesion Regulation Of T Cell Activation Positive Regulation Of Cell Activation Positive Regulation Of Immune Response Antigen Receptor-mediated Signaling Pathway Peptidyl-tyrosine Autophosphorylation Cell Activation Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Regulation Of Lymphocyte Activation Axon Guidance Blood Coagulation Hemostasis Regulation Of Immune Response Regulation Of Cell Activation Positive Regulation Of Immune System Process Leukocyte Migration Axonogenesis Axon Development Regulation Of Body Fluid Levels Cell Morphogenesis Involved In Neuron Differentiation Response To Abiotic Stimulus Fc Receptor Signaling Pathway Wound Healing Chemotaxis Regulation Of Cell Adhesion Neuron Projection Morphogenesis T Cell Receptor Signaling Pathway Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Locomotion Response To Wounding Positive Regulation Of Antigen Receptor-mediated Signaling Pathway Cell Morphogenesis Involved In Differentiation Immune Response Regulation Of Immune System Process Immune System Process Defense Response Innate Immune Response Neuron Projection Development Cell Migration Cell Projection Morphogenesis Regulation Of Phosphorus Metabolic Process
Tagcloud ?		10kb appbp2 arhgap32 bcas3 breakpoints ccdc49 coamplification col14a1 coregulator ddx5 depdc6 deptor enpp2 hoxb9 lasp1 leukaemias nrip1 oprd1 painting pcgf2 phf20l1 plec1 taok1 tiam1 timm23 trps1 unamplified usp32 zmym4