PPFIA1 and PPFIBP1

Number of citations of the paper that reports this interaction (PMID 9624153)
49

Data Source:
HPRD (in vitro, in vivo)

		PPFIA1	PPFIBP1
Gene Name		protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1	PTPRF interacting protein, binding protein 1 (liprin beta 1)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Focal Adhesion Presynaptic Active Zone	Plasma Membrane Focal Adhesion
	Molecular Function	Signal Transducer Activity Protein Binding
	Biological Process	Cell-matrix Adhesion Signal Transduction Synaptic Transmission Neurotransmitter Secretion Glutamate Secretion Negative Regulation Of Stress Fiber Assembly Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane	Cell Adhesion
Pathways		Dopamine Neurotransmitter Release Cycle Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Serotonin Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Protein-Protein Interactions		25 interactors: AGTPBP1 CAST CCNH CEP70 DTNB ERC1 ERC2 FAM161A GIT1 MBIP NCOA2 NDN PPFIA2 PPFIA3 PPFIBP1 PPFIBP2 PPP2R5D PTPRC PTPRD PTPRF PTPRG PTPRS TNNT1 TXLNA YWHAG	7 interactors: PPFIA1 PPFIA2 PPFIA3 PTPRM S100A4 YWHAG YWHAQ
Entrez ID		8500	8496
HPRD ID		11451	04390
Ensembl ID		ENSG00000131626	ENSG00000110841
Uniprot IDs		B3KVS8 Q13136	Q86W92
PDB IDs
Enriched GO Terms of Interacting Partners?		Peptidyl-tyrosine Dephosphorylation Protein Dephosphorylation Dephosphorylation Enzyme Linked Receptor Protein Signaling Pathway Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Signaling Cell Communication Cell Cycle Phase Transition Nervous System Development G2/M Transition Of Mitotic Cell Cycle Glutamate Secretion Cellular Protein Modification Process Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Transcription Initiation From RNA Polymerase I Promoter Generation Of Neurons Transcription From RNA Polymerase I Promoter Neurogenesis Cell Adhesion Signal Transduction Negative Regulation Of Protein Kinase Activity Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway Negative Regulation Of Kinase Activity Acid Secretion Mitotic Cell Cycle Phase Transition Cellular Response To Stimulus Immunoglobulin Biosynthetic Process Positive Regulation Of Hematopoietic Stem Cell Migration DNA-templated Transcription, Termination Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Transferase Activity Phosphate-containing Compound Metabolic Process Dicarboxylic Acid Transport DNA-templated Transcription, Elongation Cellular Protein Metabolic Process Negative Regulation Of Protein Phosphorylation Neuron Differentiation C-terminal Protein Deglutamylation Regulation Of Catalytic Activity Regulation Of Protein Kinase Activity Response To Stimulus Neurotransmitter Secretion Cell Surface Receptor Signaling Pathway Developmental Process Histone Acetylation Negative Regulation Of Catalytic Activity Cerebellum Development Regulation Of Kinase Activity Negative Regulation Of Phosphorylation	Glutamate Secretion Acid Secretion Dicarboxylic Acid Transport Neurotransmitter Secretion Regulation Of Neurotransmitter Levels Amino Acid Transport Neurotransmitter Transport Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Carboxylic Acid Transport Organic Acid Transport Establishment Of Localization In Cell Positive Regulation Of Mitochondrion Organization Cellular Localization Organic Anion Transport Secretion By Cell Regulation Of Mitochondrion Organization Synaptic Transmission Secretion Anion Transport Regulation Of Establishment Of Protein Localization Signaling Regulation Of Synaptic Plasticity Cell-matrix Adhesion Cell Communication Regulation Of Protein Localization Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Cell-substrate Adhesion Cell-cell Signaling Regulation Of Organelle Organization Positive Regulation Of Intracellular Transport Regulation Of Cellular Localization Negative Regulation Of Stress Fiber Assembly Regulation Of Synaptic Transmission Negative Regulation Of Actin Filament Bundle Assembly Regulation Of Short-term Neuronal Synaptic Plasticity Cell Adhesion Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane Apoptotic Signaling Pathway Positive Regulation Of Signal Transduction Transport Positive Regulation Of Organelle Organization Negative Regulation Of Protein Localization To Plasma Membrane Protein Targeting Retinal Ganglion Cell Axon Guidance Regulation Of Intracellular Transport Regulation Of Signaling Retina Layer Formation
Tagcloud ?		11q13 aberrations acgh aiming amplicon apart band breakpoints candidates ccnd1 chosen chr comprised copies cttn distinguish fadd gain homogeneously laryngeal microarray oncogene oncogenes oraov1 q13 rearrangements reinvestigated sevenfold ways
Tagcloud (Difference) ?		11q13 aberrations acgh aiming amplicon apart band breakpoints candidates ccnd1 chosen chr comprised copies cttn distinguish fadd gain homogeneously laryngeal microarray oncogene oncogenes oraov1 q13 rearrangements reinvestigated sevenfold ways
Tagcloud (Intersection) ?