PPFIA1 and PPFIBP2

Number of citations of the paper that reports this interaction (PMID 9624153)
49

Data Source:
HPRD (in vivo, in vitro)

		PPFIA1	PPFIBP2
Gene Name		protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1	PTPRF interacting protein, binding protein 2 (liprin beta 2)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Focal Adhesion Presynaptic Active Zone	Extracellular Space Intracellular
	Molecular Function	Signal Transducer Activity Protein Binding	Molecular_function
	Biological Process	Cell-matrix Adhesion Signal Transduction Synaptic Transmission Neurotransmitter Secretion Glutamate Secretion Negative Regulation Of Stress Fiber Assembly Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane
Pathways		Dopamine Neurotransmitter Release Cycle Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Serotonin Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Protein-Protein Interactions		25 interactors: AGTPBP1 CAST CCNH CEP70 DTNB ERC1 ERC2 FAM161A GIT1 MBIP NCOA2 NDN PPFIA2 PPFIA3 PPFIBP1 PPFIBP2 PPP2R5D PTPRC PTPRD PTPRF PTPRG PTPRS TNNT1 TXLNA YWHAG	10 interactors: APP CRK CRKL DTNB PPFIA1 PPFIA2 PPFIA3 PRNP PTPRC TSG101
Entrez ID		8500	8495
HPRD ID		11451	04391
Ensembl ID		ENSG00000131626	ENSG00000166387
Uniprot IDs		B3KVS8 Q13136	Q8ND30
PDB IDs			3QH9
Enriched GO Terms of Interacting Partners?		Peptidyl-tyrosine Dephosphorylation Protein Dephosphorylation Dephosphorylation Enzyme Linked Receptor Protein Signaling Pathway Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Signaling Cell Communication Cell Cycle Phase Transition Nervous System Development G2/M Transition Of Mitotic Cell Cycle Glutamate Secretion Cellular Protein Modification Process Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Transcription Initiation From RNA Polymerase I Promoter Generation Of Neurons Transcription From RNA Polymerase I Promoter Neurogenesis Cell Adhesion Signal Transduction Negative Regulation Of Protein Kinase Activity Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway Negative Regulation Of Kinase Activity Acid Secretion Mitotic Cell Cycle Phase Transition Cellular Response To Stimulus Immunoglobulin Biosynthetic Process Positive Regulation Of Hematopoietic Stem Cell Migration DNA-templated Transcription, Termination Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Transferase Activity Phosphate-containing Compound Metabolic Process Dicarboxylic Acid Transport DNA-templated Transcription, Elongation Cellular Protein Metabolic Process Negative Regulation Of Protein Phosphorylation Neuron Differentiation C-terminal Protein Deglutamylation Regulation Of Catalytic Activity Regulation Of Protein Kinase Activity Response To Stimulus Neurotransmitter Secretion Cell Surface Receptor Signaling Pathway Developmental Process Histone Acetylation Negative Regulation Of Catalytic Activity Cerebellum Development Regulation Of Kinase Activity Negative Regulation Of Phosphorylation	Glutamate Secretion Acid Secretion Dicarboxylic Acid Transport Neurotransmitter Secretion Regulation Of Neurotransmitter Levels Regulation Of Protein Phosphorylation Cellular Copper Ion Homeostasis Secretion By Cell Establishment Of Localization In Cell Amino Acid Transport Neurotransmitter Transport Copper Ion Homeostasis Regulation Of Phosphorylation Secretion Cellular Localization Regulation Of Phosphorus Metabolic Process Regulation Of Protein Kinase Activity Activation Of Protein Kinase Activity Regulation Of Kinase Activity Carboxylic Acid Transport Organic Acid Transport Regulation Of Cell Cycle Activation Of MAPKK Activity Regulation Of Signaling Axon Guidance Regulation Of Cellular Protein Metabolic Process Cellular Metal Ion Homeostasis Transport Organic Anion Transport Cellular Cation Homeostasis Positive Regulation Of MAPK Cascade Positive Regulation Of Cellular Protein Metabolic Process Cellular Ion Homeostasis Positive Regulation Of Protein Kinase Activity Metal Ion Homeostasis Regulation Of Protein Metabolic Process Cell Adhesion Positive Regulation Of Kinase Activity Positive Regulation Of Protein Metabolic Process Immunoglobulin Biosynthetic Process Synaptic Growth At Neuromuscular Junction Positive Regulation Of Hematopoietic Stem Cell Migration Axonogenesis Cellular Chemical Homeostasis Signaling Positive Regulation Of Transferase Activity Ion Homeostasis Axon Development Cell Communication Collateral Sprouting In Absence Of Injury
Tagcloud ?		11q13 aberrations acgh aiming amplicon apart band breakpoints candidates ccnd1 chosen chr comprised copies cttn distinguish fadd gain homogeneously laryngeal microarray oncogene oncogenes oraov1 q13 rearrangements reinvestigated sevenfold ways	acaa1 analogous ap1m2 aspirates cgn combat dcn ddr1 deadly ec ecs efemp2 endometrial eps8l2 fastkd1 gmip ikbke minimally noncarcinoma p2rx4 p4hb phkg2 ppp1r16a rassf7 rnf183 sirt6 socs2 tjp3 uterine
Tagcloud (Difference) ?		11q13 aberrations acgh aiming amplicon apart band breakpoints candidates ccnd1 chosen chr comprised copies cttn distinguish fadd gain homogeneously laryngeal microarray oncogene oncogenes oraov1 q13 rearrangements reinvestigated sevenfold ways	acaa1 analogous ap1m2 aspirates cgn combat dcn ddr1 deadly ec ecs efemp2 endometrial eps8l2 fastkd1 gmip ikbke minimally noncarcinoma p2rx4 p4hb phkg2 ppp1r16a rassf7 rnf183 sirt6 socs2 tjp3 uterine
Tagcloud (Intersection) ?