ETHE1 and LRIF1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ETHE1	LRIF1
Description		ETHE1 persulfide dioxygenase	ligand dependent nuclear receptor interacting factor 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Matrix	Chromosome, Telomeric Region Barr Body Nucleus Nucleoplasm Chromosome Nuclear Matrix Centriolar Satellite
	Molecular Function	Iron Ion Binding Protein Binding Oxidoreductase Activity Identical Protein Binding Metal Ion Binding Sulfur Dioxygenase Activity Dioxygenase Activity	Protein Binding Nuclear Retinoic Acid Receptor Binding
	Biological Process	Glutathione Metabolic Process Hydrogen Sulfide Metabolic Process	Regulation Of DNA-templated Transcription Dosage Compensation By Inactivation Of X Chromosome
Pathways		Sulfide oxidation to sulfate
Drugs
Diseases
GWAS			Bone mineral content ( 31790847) Intraocular pressure ( 30591961)
Interacting Genes		9 interacting genes: APP ATG9A ATP6V1H GORASP2 IGSF21 KRTAP19-2 LRIF1 RELA TXN2	143 interacting genes: AKR1C3 ANKRD24 ANXA1 ANXA7 APLP1 ARL3 ATF3 ATP1B1 BANP BARD1 BMI1 BOC BRD7 BRMS1 CALR CBX1 CBX5 CCDC106 CDC42 CDKN1A CDKN2C CETN3 CHD3 CKMT2 COX17 CPE CRACR2A CRADD CRCP CRCT1 CRIPTO DDIT4 EIF6 ESR1 ETHE1 FAS FEZ1 FHL2 FOSL2 FXR1 GADD45G GC GIT1 GPRASP2 GSTM4 H3-4 HAP1 HLA-DQA1 HMGB1 HMOX2 HSPB1 HSPB3 HSPBP1 HSPE1 ID2 IMMT KAT5 KAT7 KBTBD7 KCNE3 KLHL20 KLK10 LAMA4 LAMTOR5 MAD2L1BP MLLT3 MNAT1 MOB4 MPHOSPH6 MRPS12 MRPS6 NACA NOC2L NR3C1 NRBP1 NTAQ1 PAEP PAFAH1B3 PCDHA4 PDCD5 PFDN1 PFN1 PIAS4 PIN1 PLEKHA4 PNP POLR1C POLR2C POLR3F PPARG PQBP1 PRKAB2 PRKAR2A PRMT1 PSG9 PSMD11 PSMD2 PSPC1 RAB27A RAP1B RARA RBM5 RCC1 RFC5 RHOH RIT1 RNF10 RORA RPA2 RPL37A RPLP1 RRM1 S100A8 SAT1 SELENBP1 SERPINB9 SETDB1 SMN1 SNRPN SNU13 SPATA18 SPG7 STX5 SULT1E1 SUPT4H1 SUV39H2 TAF1D TGIF1 THRB TK1 TRBV2 TRDMT1 TSC22D1 TSEN15 TSPAN6 UBE2V2 UNC119 VIM VPS26C WDR62 WWC1 ZNF24 ZNF410
Entrez ID		23474	55791
HPRD ID		09764	17975
Ensembl ID		ENSG00000105755	ENSG00000121931
Uniprot IDs		A0A0S2Z580 A0A0S2Z5B3 A0A0S2Z5N8 B2RCZ7 O95571	Q5T3J3
PDB IDs		4CHL
Enriched GO Terms of Interacting Partners?		Negative Regulation Of MiRNA Transcription Positive Regulation Of Amyloid Precursor Protein Catabolic Process Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Positive Regulation Of Interleukin-1 Production Response To Interleukin-1 Regulation Of Amyloid Precursor Protein Catabolic Process Growth Cone Lamellipodium Synaptic Membrane Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Non-canonical NF-kappaB Signal Transduction Regulation Of Response To Calcium Ion Regulation Of Interleukin-1 Production Regulation Of MiRNA Transcription Regulation Of MiRNA Metabolic Process Positive Regulation Of Interleukin-6 Production Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Positive Regulation Of Interleukin-1 Beta Production Lipoprotein Particle Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To CAMP Regulation Of Interleukin-1 Beta Production NF-kappaB P50/p65 Complex Positive Regulation Of Schwann Cell Differentiation Response To Cobalamin Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Gene Expression Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Regulation Of Schwann Cell Differentiation NF-kappaB Complex Prolactin Signaling Pathway Response To Purine-containing Compound Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Recycling Endosome Positive Regulation Of Amyloid Fibril Formation	Nucleus Nucleoplasm Protein Binding Cytoplasm Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Programmed Cell Death Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Regulation Of Apoptotic Process Chromatin Binding Positive Regulation Of Programmed Cell Death Regulation Of Macromolecule Metabolic Process Negative Regulation Of RNA Metabolic Process Nuclear Receptor Activity Regulation Of Intracellular Signal Transduction Negative Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Population Proliferation Regulation Of Primary Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Cytosol Positive Regulation Of Apoptotic Process Nucleolus Negative Regulation Of Transcription By RNA Polymerase II Biological_process Negative Regulation Of DNA-templated Transcription Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Development Negative Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Regulation Of Hemopoiesis Chromatin Organization Regulation Of Cell Differentiation Mononuclear Cell Differentiation Regulation Of Lymphocyte Differentiation Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Signal Transduction Positive Regulation Of Fibroblast Proliferation DNA-directed RNA Polymerase Activity Positive Regulation Of Biosynthetic Process Chromatin Remodeling Regulation Of Cell Cycle Process Regulation Of DNA Repair Regulation Of Cell Cycle G1/S Phase Transition
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