CITED1

Description		Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Chromatin Binding Transcription Coactivator Activity Protein Binding Protein Homodimerization Activity LBD Domain Binding Co-SMAD Binding
	Biological Process	Vasculogenesis Metanephros Development Branching Involved In Ureteric Bud Morphogenesis Placenta Development Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Nucleocytoplasmic Transport Apoptotic Process Transforming Growth Factor Beta Receptor Signaling Pathway Brain Development Positive Regulation Of Gene Expression Cell Differentiation Negative Regulation Of Wnt Signaling Pathway Melanocyte Differentiation Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Response To Lipopolysaccharide Response To Insulin Response To Cytokine Response To Type II Interferon Melanin Biosynthetic Process Regulation Of Apoptotic Process Pigmentation Negative Regulation Of Neuron Apoptotic Process Response To Estrogen Negative Regulation Of Osteoblast Differentiation Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Response To CAMP Mesenchymal To Epithelial Transition SMAD Protein Signal Transduction Labyrinthine Layer Development Response To Interleukin-1 Response To Interleukin-2 Response To Interleukin-4 Response To Interleukin-6 Response To Interleukin-9 Response To Interleukin-11 Response To Parathyroid Hormone Response To Transforming Growth Factor Beta Regulation Of Kidney Development Positive Regulation Of Mesenchymal Stem Cell Proliferation
Pathways		Activation of the TFAP2 (AP-2) family of transcription factors Estrogen-dependent gene expression
Drugs
Diseases
GWAS		Autism spectrum disorder ( 34069769) Chloride levels ( 29403010) Sodium levels ( 29403010)
Interacting Genes		8 interacting genes: CREBBP EP300 ESR1 HSPA8 LNX1 SMAD4 TFAP2B TFAP2C
Entrez ID		4435
HPRD ID		02146
Ensembl ID		ENSG00000125931
Uniprot IDs		Q99966
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription Coactivator Binding Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Transcription By RNA Polymerase II Negative Regulation Of RNA Metabolic Process Histone H3K27 Acetyltransferase Activity Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation Peptide Lactyltransferase (CoA-dependent) Activity DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II Chromatin Binding Chromatin Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation Nucleic Acid Metabolic Process Transcription Regulator Complex Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Sebaceous Gland Development RNA Metabolic Process Anatomical Structure Morphogenesis Regulation Of Cellular Response To Growth Factor Stimulus Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process N-terminal Protein Amino Acid Acetylation Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Stem Cell Differentiation Peptidyl-lysine Acetylation Male Gonad Development Nucleobase-containing Compound Biosynthetic Process Regulation Of Cellular Response To Heat Positive Regulation Of RNA Biosynthetic Process Negative Regulation Of Metabolic Process Positive Regulation Of DNA-templated Transcription Mammary Gland Epithelial Cell Proliferation DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Gonad Development Regulation Of Innate Immune Response Positive Regulation Of RNA Metabolic Process Acetyltransferase Activity Cellular Response To Lectin Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Stimulatory C-type Lectin Receptor Signaling Pathway Macromolecule Metabolic Process Muscle Tissue Development Uterus Development
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