PKP4 and PGAM1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		PKP4	PGAM1
Description		plakophilin 4	phosphoglycerate mutase 1
Image		No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cornified Envelope Nucleus Cytoplasm Spindle Cytoskeleton Plasma Membrane Cell-cell Junction Adherens Junction Cytoplasmic Side Of Plasma Membrane Postsynaptic Density Membrane Cell Junction Desmosome Midbody Organelle Cell-cell Contact Zone Perinuclear Region Of Cytoplasm Spindle Midzone Anchoring Junction Mitotic Spindle	Extracellular Region Cytoplasm Cytosol Membrane Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding Cadherin Binding	Catalytic Activity Bisphosphoglycerate Mutase Activity Phosphoglycerate Mutase Activity Protein Binding Hydrolase Activity Isomerase Activity Intramolecular Phosphotransferase Activity Protein Kinase Binding
	Biological Process	Cell-cell Junction Assembly Cell Adhesion Cell-cell Signaling Regulation Of Cell Adhesion Positive Regulation Of Cytokinesis Regulation Of Rho Protein Signal Transduction Cell-cell Adhesion	Gluconeogenesis Glycolytic Process Canonical Glycolysis
Pathways		Keratinization Formation of the cornified envelope RND3 GTPase cycle RND2 GTPase cycle RND1 GTPase cycle	Neutrophil degranulation Glycolysis Gluconeogenesis
Drugs			Copper Artenimol
Diseases
GWAS		Borderline personality disorder ( 28632202) Obesity-related traits ( 23251661) Restless legs syndrome ( 29029846)
Interacting Genes		20 interacting genes: ATPAF2 CDH1 CDH2 CDH5 DSC3 DSP ERBIN GABARAP GOLGA2 LNX1 LZTS2 MINK1 OGT OSGEP PAXIP1 PDZD2 PGAM1 PSEN1 TRIM23 UBASH3B	8 interacting genes: ARL4D CEBPA DCTN1 ERBB2 PCNA PKP4 UNC5CL XRCC6
Entrez ID		8502	5223
HPRD ID		05043	01392
Ensembl ID		ENSG00000144283	ENSG00000171314
Uniprot IDs		Q99569	B7Z9E5 P18669 Q6FHU2
PDB IDs			1YFK 1YJX 4GPI 4GPZ 5Y2I 5Y2U 5Y35 5Y64 5Y65 5ZRM 5ZS8 6ISN 7XB7 7XB8 7XB9 8IT4 8IT5 8IT6 8IT7 8IT8 8ITB 8ITC 8ITD
Enriched GO Terms of Interacting Partners?		Desmosome Cell Junction Cell Adhesion Gamma-catenin Binding Adherens Junction Organization Cell-cell Adhesion Cell-cell Junction Catenin Complex Beta-catenin Binding Anchoring Junction Intracellular Protein Localization Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Cell-cell Adhesion Mediated By Cadherin Cell Junction Organization Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Cytoplasm Cadherin Binding Fascia Adherens Cell-cell Junction Organization Adherens Junction Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Desmosome Organization Postsynapse Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Synapse Organization Protein Localization To Cell-cell Junction Smooth Endoplasmic Reticulum Brain Morphogenesis Regulation Of Cellular Localization Cell-cell Junction Assembly Regulation Of Protein Localization To Synapse Regulation Of Protein Localization Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Receptor Localization To Synapse Plasma Membrane Protein Glycosylation Macromolecule Glycosylation Regulation Of Rac Protein Signal Transduction Cell-cell Adhesion Mediator Activity Regulation Of Protein Localization To Nucleus Cytoskeleton Organization Glycosylation Regulation Of Protein Catabolic Process Positive Regulation Of Protein Import Into Nucleus Protein Tyrosine Kinase Binding Cellular Component Assembly Regulation Of Protein Localization To Membrane Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Core Promoter Binding Protein N-acetylglucosaminyltransferase Complex	Protein-containing Complex Binding Cellular Response To Xenobiotic Stimulus Animal Organ Regeneration RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Dexamethasone Neuromuscular Junction Development Positive Regulation Of Catalytic Activity Receptor Tyrosine Kinase Binding Damaged DNA Binding PCNA Complex Replisome CHOP-C/EBP Complex Negative Regulation Of Hemopoiesis Regulation Of Hemopoiesis Regeneration Response To Vitamin B2 White Fat Cell Proliferation Liver Development Response To Glucocorticoid Response To Corticosteroid C/EBP Complex Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Cell Cortex Region Mitotic Spindle Positive Regulation Of Neuromuscular Junction Development Spindle Pole Cell Junction Organization Negative Regulation Of Immature T Cell Proliferation In Thymus RNA Polymerase I Core Binding Positive Regulation Of Kinase Activity Positive Regulation Of Protein Kinase Activity ErbB-3 Class Receptor Binding ERBB3:ERBB2 Complex Regulation Of Catalytic Activity Immature T Cell Proliferation In Thymus Regulation Of Rho Protein Signal Transduction ERBB2-ERBB4 Signaling Pathway DNA End Binding Cellular Hyperosmotic Salinity Response Telomere Maintenance DNA-dependent Protein Kinase Complex Ku70:Ku80 Complex Telomere Organization Positive Regulation Of Deoxyribonuclease Activity PCNA-p21 Complex DNA Polymerase Processivity Factor Activity Mitotic Telomere Maintenance Via Semi-conservative Replication Dinucleotide Insertion Or Deletion Binding Leading Strand Elongation
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