MED10 and ARHGDIG

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MED10	ARHGDIG
Description		mediator complex subunit 10	Rho GDP dissociation inhibitor gamma
Image			No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Mediator Complex Core Mediator Complex	Cytoplasm Cytosol Plasma Membrane Membrane Cytoplasmic Vesicle
	Molecular Function	Transcription Coregulator Activity Protein Binding Ubiquitin Protein Ligase Activity	GDP-dissociation Inhibitor Activity Rho GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding GTPase Regulator Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Protein Ubiquitination Positive Regulation Of Transcription Elongation By RNA Polymerase II Somatic Stem Cell Population Maintenance Positive Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II	Blastocyst Hatching Negative Regulation Of Cell Adhesion Rho Protein Signal Transduction Regulation Of Protein Localization
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation RSV-host interactions MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis	RHOB GTPase cycle CDC42 GTPase cycle RHOH GTPase cycle RHOG GTPase cycle
Drugs
Diseases
GWAS			Body mass index ( 26426971)
Interacting Genes		13 interacting genes: ABI2 ARHGDIG CEBPA ESR1 ESR2 FUCA1 HNF4A KDM4B MOB4 NAP1L1 PEBP1 SYCE1L TRIM45	12 interacting genes: AGTR1 BICRAL CDC42 CEP170P1 KXD1 MED10 RAC1 RHOA RHOB RHOG RHOH TACC3
Entrez ID		84246	398
HPRD ID		14680	04163
Ensembl ID		ENSG00000133398	ENSG00000242173
Uniprot IDs		Q9BTT4	F1T0H7 Q99819
PDB IDs		7EMF 7ENA 7ENC 7ENJ 7LBM 7NVR 8GXQ 8GXS 8T9D 8TQW 8TRH
Enriched GO Terms of Interacting Partners?		Nuclear Estrogen Receptor Activity Nuclear Receptor Activity Estrogen Response Element Binding Chromatin Estrogen Receptor Signaling Pathway Nuclear Steroid Receptor Activity Steroid Binding Sequence-specific DNA Binding Chromatin Binding Cellular Response To Estradiol Stimulus Intracellular Receptor Signaling Pathway RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Regulation Of Ornithine Metabolic Process Intracellular Signal Transduction DNA-binding Transcription Factor Activity Response To Vitamin B2 C/EBP Complex Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Alpha-L-fucosidase Activity Zonula Adherens Assembly	Small GTPase-mediated Signal Transduction Actin Filament Organization GTPase Activity GTP Binding Rho Protein Signal Transduction Intracellular Signaling Cassette Supramolecular Fiber Organization Regulation Of Synapse Organization Wnt Signaling Pathway, Planar Cell Polarity Pathway Establishment Or Maintenance Of Cell Polarity Membrane Invagination Non-canonical Wnt Signaling Pathway Positive Regulation Of Stress Fiber Assembly Focal Adhesion Protein Kinase Binding Positive Regulation Of Actin Filament Bundle Assembly G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Postsynapse G Protein Activity Regulation Of Cytoskeleton Organization Thioesterase Binding Endothelial Tube Morphogenesis Regulation Of Stress Fiber Assembly Secretory Granule Membrane Regulation Of Modification Of Postsynaptic Structure Chemotaxis Establishment Of Epithelial Cell Apical/basal Polarity Intracellular Signal Transduction Regulation Of Actin Cytoskeleton Organization Locomotion Angiotensin-activated Signaling Pathway Regulation Of Modification Of Synaptic Structure Actin Cytoskeleton Organization GTP-dependent Protein Binding Establishment Of Apical/basal Cell Polarity Regulation Of Actin Filament-based Process Regulation Of Reactive Oxygen Species Metabolic Process Polarized Epithelial Cell Differentiation Regulation Of Postsynapse Organization Establishment Of Monopolar Cell Polarity Establishment Or Maintenance Of Monopolar Cell Polarity Positive Regulation Of Developmental Process Actin Filament-based Process Rac Protein Signal Transduction Positive Regulation Of Lamellipodium Assembly Nuclear Migration Regulation Of Systemic Arterial Blood Pressure Mediated By A Chemical Signal Regulation Of Microtubule Cytoskeleton Organization Establishment Of Epithelial Cell Polarity Cerebral Cortex Cell Migration
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?