MED10 and PEBP1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		MED10	PEBP1
Gene Name		mediator complex subunit 10	phosphatidylethanolamine binding protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Mediator Complex	Nucleus Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	RNA Polymerase II Transcription Cofactor Activity Protein Binding	Serine-type Endopeptidase Inhibitor Activity Protein Binding ATP Binding Phosphatidylethanolamine Binding Enzyme Binding Protein Kinase Binding Poly(A) RNA Binding
	Biological Process	Transcription Initiation From RNA Polymerase II Promoter Gene Expression Stem Cell Maintenance Positive Regulation Of Transcription From RNA Polymerase II Promoter	Negative Regulation Of Endopeptidase Activity
Pathways		PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: ESR1 ESR2 HNF4A KDM4B MOB4 NAP1L1 PEBP1	20 interactors: ADRBK1 CACHD1 CHUK GSDMB IKBKB MAP2K1 MAP3K14 MAP3K7 MAPK1 MED10 NKX3-1 NR2C2 PPARD PRKCA PRKCB PRKCD PRKCG PRKCZ RAF1 STC2
Entrez ID		84246	5037
HPRD ID		14680	06850
Ensembl ID		ENSG00000133398	ENSG00000089220
Uniprot IDs		Q9BTT4	B4DRT4 D9IAI1 P30086
PDB IDs			1BD9 1BEH 2L7W 2QYQ
Enriched GO Terms of Interacting Partners?		Steroid Hormone Mediated Signaling Pathway Hormone-mediated Signaling Pathway Vagina Development Uterus Development Intracellular Estrogen Receptor Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Steroid Hormone Stimulus Female Genitalia Development Intracellular Receptor Signaling Pathway DNA-templated Transcription, Initiation Prostate Gland Epithelium Morphogenesis Prostate Gland Morphogenesis Sex Differentiation Genitalia Development Cellular Response To Organic Cyclic Compound Ovarian Follicle Development Prostate Gland Development Cellular Response To Lipid Intracellular Steroid Hormone Receptor Signaling Pathway Response To Steroid Hormone Ovulation Cycle Process Female Gonad Development Regulation Of Cell Proliferation Ovulation Cycle Cellular Response To Hormone Stimulus Development Of Primary Female Sexual Characteristics Chromatin Organization Prostate Epithelial Cord Elongation Negative Regulation Of Cell Growth Developmental Process Involved In Reproduction Gland Morphogenesis Positive Regulation Of Cholesterol Homeostasis Cellular Macromolecule Biosynthetic Process Response To Lipid Regulation Of Growth Hormone Receptor Signaling Pathway Epithelial Cell Maturation Involved In Prostate Gland Development Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Hormone-mediated Apoptotic Signaling Pathway Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Epithelial Cell Development Response To Organic Cyclic Compound Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Branch Elongation Involved In Mammary Gland Duct Branching Antral Ovarian Follicle Growth Gonad Development Response To Hormone Development Of Primary Sexual Characteristics Negative Regulation Of Growth	Cellular Response To Organic Substance Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Positive Regulation Of Intracellular Signal Transduction Cellular Response To Growth Factor Stimulus Response To Growth Factor Response To Organic Substance Enzyme Linked Receptor Protein Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Signal Transduction Protein Phosphorylation Cellular Response To Fibroblast Growth Factor Stimulus Vascular Endothelial Growth Factor Receptor Signaling Pathway Response To Fibroblast Growth Factor Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Intracellular Signal Transduction Phosphorylation Intracellular Signal Transduction Platelet Activation Innate Immune Response Immune Response-regulating Cell Surface Receptor Signaling Pathway Peptidyl-threonine Phosphorylation Positive Regulation Of Immune System Process Toll-like Receptor 5 Signaling Pathway Regulation Of Signal Transduction Response To Stress Immune Response Regulation Of Immune System Process Toll-like Receptor 10 Signaling Pathway Signal Transduction Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Defense Response Phosphate-containing Compound Metabolic Process Toll-like Receptor 2 Signaling Pathway Fc Receptor Signaling Pathway Toll-like Receptor 9 Signaling Pathway Response To Wounding Immune Response-regulating Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Protein Kinase Activity Activation Of MAPKK Activity MyD88-independent Toll-like Receptor Signaling Pathway Positive Regulation Of Phospholipase Activity Toll-like Receptor 3 Signaling Pathway Regulation Of Signaling
Tagcloud ?		adapted bipolar colonies constituent desired ends front glycogen gsk3beta inositol integrations intergenic linc lithium mood msi2 mutated neuroblastoma pms1 presumed proliferate race readily salts screen stabilizing sy5y trapped variously	aspects bio blotting cytoskeleton differentially dimensional downregulated downregulation electrophoresis eleven elucidate expressions gastric gastritis gel matched mucosa neuropolypeptide oxidation phosphatidylethanolamine preliminarily rt ten thioredoxin txndc5 upregulated upregulation validated varioliform
Tagcloud (Difference) ?		adapted bipolar colonies constituent desired ends front glycogen gsk3beta inositol integrations intergenic linc lithium mood msi2 mutated neuroblastoma pms1 presumed proliferate race readily salts screen stabilizing sy5y trapped variously	aspects bio blotting cytoskeleton differentially dimensional downregulated downregulation electrophoresis eleven elucidate expressions gastric gastritis gel matched mucosa neuropolypeptide oxidation phosphatidylethanolamine preliminarily rt ten thioredoxin txndc5 upregulated upregulation validated varioliform
Tagcloud (Intersection) ?